Fate of fructo-oligosaccharides in the human intestine

British Journal of Nutrition

Volumn 76, Issue 2, 1996, Pages 211-221

  Alles, Martine S ^a   Hautvast, Joseph G A J ^a   Nagengast, Fokko M ^b   Hartemink, Ralf ^a   Van Laere, Katrien M J ^a   Jansen, Jan B M J ^b  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Breath hydrogen; Colon; Fructo oligosaccharides; Short chain fatty acids

Indexed keywords

FRUCTOSE OLIGOSACCHARIDE; GLUCOSE; HYDROGEN; SHORT CHAIN FATTY ACID;

ADULT; ARTICLE; BREATH ANALYSIS; CLINICAL TRIAL; COLON; COLON FLORA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DRUG METABOLISM; FECES ANALYSIS; FERMENTATION; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PH; RANDOMIZED CONTROLLED TRIAL;

ADULT; BREATH TESTS; COLON; CROSS-OVER STUDIES; DIET; FATTY ACIDS, VOLATILE; FECES; FERMENTATION; GLUCOSE; HUMANS; HYDROGEN; MALE; OLIGOSACCHARIDES;

EID: 0029791623     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN19960026     Document Type: Article

References (33)

1. Cummings, J. H., Bingham, S. A., Heaton, K. W. & Eastwood, M. A. (1992). Fecal weight, colon cancer risk, and dietary intake of nonstarch polysaccharides (dietary fibre). Gastroenterology 103, 1783-1789.
2. Cummings, J. H., Pomare, E. W., Branch, W. J., Naylor, C. P. E. & Macfarlane, G. T. (1987). Short-chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 28, 1221-1227.
3. Gibson, G. R., Beatty, E. R., Wang, Z. & Cummings, J. H. (1995). Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology 108, 975-982.
4. Hayakawa, K., Mizutani, J., Wada, K., Masai, T., Yoshihara, I. & Mitsuoka, T. (1990). Effects of soybean oligosaccharides on human faecal flora. Microbial Ecology in Health and Disease 3, 293-303.
5. Heaton, K. W., Radvan, J., Cripps, H., Mountford, R. A., Braddon, F. E. M. & Hughes, A. O. (1992). Defecation frequency and timing, and stool form in the general population: a prospective study. Gut 33, 818-824.
6. Hidaka, H., Eida, T., Takizawa, T., Tokunaga, T. & Tashiro, Y. (1986). Effects of fructooligosaccharides on intestinal flora and human health. Bifidobacteria Microflora 5, 37-50.
7. 2 breath test. Scandinavian Journal of Gastroenterology 17, 373-378.
8. Ito, M., Deguchi, Y., Miyamori, A., Matsumoto, K., Kikuchi, H., Kobayashi, Y., Tajema, Y. & Kan, T. (1990). Effects of administration of galactooligosaccharides on the human faecal microflora, stool weight and abdominal sensation. Microbial Ecology in Health and Disease 3, 285-292.
9. Koo, M. & Rao, A. V. (1991). Long-term effect of Bifidobacteria and Neosugar on precursor lesions of colonic cancer in CF1 mice. Nutrition and Cancer 16, 249-257.
10. Leclercq, C., Avalle, V., Ranaldi, L., Toti, E. & Ferro-Luzzi, A. (1990). Simplifying the lithium-marker technique used to assess the dietary intake of discretionary sodium in population studies. Clinical Science 79, 227-231.
11. McBurney, M. I. (1991). Starch malabsorption and stool excretion are influenced by the menstrual cycle in women consuming low-fibre western diets. Scandinavian Journal of Gastroenterology 26, 880-886.
12. Macfarlane, G. T., Gibson, G. R. & Cummings, J. H. (1992) Comparison of fermentation reactions in different regions of the human colon. Journal of Applied Bacteriology 72, 57-64.
13. Masai, T., Wada, K., Hayakawa, K., Yoshihara, I. & Mitsuoka, T. (1987). Effects of soybean oligosaccharides on human intestinal flora and metabolic activities. Japanese Journal of Bacteriology 42, 313-325.
14. Ministerie van Welzijn, Volksgezondheid en Cultuur & Ministerie van Landbouw en Visserij (1988). Wat eet Nederland: resultaten van de voedselconsumptiepeiling 1987-1988. Rijswijk: Centrale Directie Voorlichting, Documentatie en Bibliotheek.
15. Mitsuoka, T. (1990). Bifidobacteria and their role in human health. Journal of Industrial Microbiology 6, 263-268.
16. Mitsuoka, T., Hidaka, H. & Eida, T. (1987). Effect of fructo-oligosaccharides on intestinal microflora. Die Nahrung 31, 427-436.
17. Modler, H. W., McKellar, R. C. & Yaguchi, M. (1990). Bifidobacteria and bifidogenic factors. Canadian Institute of Food Science and Technology 23, 29-41.
18. 4) production in vitro and excretion in breath. Gastroenterology 94, A319.
19. Nilsson, U. & Björck, I. (1988). Availability of cereal fructans and inulin in the rat intestinal tract. Journal of Nutrition 118, 1482-1486.
20. Oku, T., Tokunaga, T. & Hosoya, N. (1984). Nondigestibility of a new sweetener, 'Neosugar', in the rat. Journal of Nutrition 114, 1574-1581.
21. Rumessen, J. J. (1992). Hydrogen and methane breath tests for evaluation of resistant carbohydrates. European Journal of Clinical Nutrition 46, S77-S90.
22. Rumessen, J. J., Bodé, S., Hamberg, O. & Gudmand-Hoyer, E. (1990a). Fructans of Jerusalem artichokes: intestinal transport, absorption, fermentation, and influence on blood glucose, insulin, and C-peptide responses in healthy subjects. American Journal of Clinical Nutrition 52, 675-681.
23. Rumessen, J. J., Hamberg, O. & Gudmand-Hoyer, E. (1990b). Interval sampling of end-expiratory hydrogen concentrations to quantify carbohydrate malabsorption. Gut 31, 37-42.
24. Sanchez-Castillo, C. P., Seidell, J. & James, W. P. T. (1987). The potential use of lithium as a marker for the assessment of the sources of dietary salt : cooking studies and physiological experiments in men. Clinical Science 72, 81-86.
25. Spiegel, J. E., Rose, R., Karabell, P., Frankos, V. H. & Schmitt, D. F. (1994). Safety and benefits of fructooligosaccharides as food ingredients. Food Technology January, 85-89.
26. Stephen, A. M. & Cummings, J. H. (1980). The microbial contribution to human faecal mass. Journal of Medical Microbiology 1345, 45-56.
27. Stichting Nederlands Voedingsstoffenbestand (NEVO) (1986). NEVO Table (in Dutch), The Hague: The Netherlands Bureau for Food and Nutrition Education.
28. Stone-Dorshow, T. & Levitt, M. D. (1987). Gaseous response to ingestion of a poorly absorbed fructooligosaccharide sweetener. American Journal of Clinical Nutrition 46, 61-65.
29. Tokunaga, T., Oku, T. & Hosoya, N. (1989). Utilization and excretion of a new sweetener, fructooligosaccharide (neosugar), in rats. Journal of Nutrition 119, 553-559.
30. van Houwelingen, R., Nordoy, A., van der Beek, E., Houtsmuller, U., de Metz, M. & Hornstra, G. (1987). Effect of a moderate fish intake on blood pressure, bleeding time, hematology, and clinical chemistry in healthy males. American Journal of Clinical Nutrition 46, 424-436.
31. van Munster, I. P., Tangerman, A. & Nagengast, F. M. (1994). Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation. Digestive Diseases and Sciences 39, 834-842.
32. Wang, X. & Gibson, G. R. (1993). Effects of the in vitro fermentation of oligofructose and inulin by bacteria growing in the human large intestine. Journal of Applied Bacteriology 75, 373-380.
33. Wolever, T. M. S. & Jenkins, D. J. A. (1986). The use of the glycemic index in predicting the blood glucose response to mixed meals. American Journal of Clinical Nutrition 43, 167-172.