The influence of five selected processing and formulation variables on the release of riboflavin from pellets produced in a rotary processor

S.T.P. Pharma Sciences

Volumn 6, Issue 5, 1996, Pages 335-340

  Vertommen, J ^a   Kinget, R ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Dissolution; Formulation; Microcrystalline cellulose; Pellet; Processing; Riboflavin; Rotary processor

Indexed keywords

CELLULOSE; LACTOSE; MICROCRYSTALLINE CELLULOSE; RIBOFLAVIN;

ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY;

EID: 0029790835     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. VERTOMMEN J. and KINGET R. - The influence of five selected processing and formulation variables on the production of pellets using a rotary processor. - 40th Annual Congress of the International Association for Pharmaceutical Technology, Mainz, 9-12 March 1994 - Eur. J. Pharm. Biopharm., 40 (Suppl.), p. 29S.
2. LANGGUTH P. - Anforderungen an Retardarzneiformen: Pharmakokinetische und pharmakodynamische Aspekte. - Kurs 102 APV: Feste, perorale Retardarzneiformen, Stuttgart, 1994.
3. GHEBRE-SELLASSIE I. - Pellets, a general overview. - In : Pharmaceutical Pelletization Technology, I. Ghebre-Sellassie Ed., Marcel Dekker, Basel, 1989, pp. 1-13.
4. HIGUCHI T. - Mechanism of sustained-action medication: Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J. Pharm. Sci., 52, 1145-1149, 1963.
5. O'CONNER R.E. and SCHWARTZ J.B. - Drug release mechanism from a microcrystalline cellulose pellet system. - Pharm. Res., 10 , 356-361, 1993.
6. LANGENBUCHER F. - Linearization of dissolution rate curves by the Weibull distribution. - J. Pharm. Pharmacol., 24, 979-981, 1972.
7. LANGENBUCHER F. - Parametric representation of dissolution rate curves by the RRSBW distribution. - Pharm. Ind., 38, 472-477, 1976
8. FONNERD. E. Jr, BUCK J.R. and BANKER G.S. - Mathematical optimization techniques in drug product design and process analysis. - J. Pharm. Sci., 59, 1587-1596, 1970.
9. PHILIPPE J. - Les méthodes statistiques en pharmacie et en chimie - Masson & Cie., Paris, 1967, pp. 205-210.
10. O'CONNER R.E. and SCHWARTZ J.B. - Spheronization. II. Drug release from drug-diluent mixtures. - Drug Dev. Ind. Pharm., 11, 1837-1857, 1985.
11. GHALI E.S., KLINGER G.H. and SCHWARTZ J.B. - Modified drug release from beads prepared with combinations of two grades of microcrystalline cellulose. - Drug Dev. Ind. Pharm., 15, 1455-1473, 1989.
12. ZHANG G., SCHWARTZ J.B. and SCHNAARE R.L. - Effect of spheronization technique on drug release from uncoated beads. - Drug Dev. Ind. Pharm., 16, 1171-1184, 1990.
13. LAAKSO R. and EERIKÄINEN S. - Effects of core components on indomethacin release from film-coated granules. - Int. J Pharm., 67, 79-88, 1991.
14. PINTO J.F., BUCKTON G. and NEWTON J.M. -The influence of four selected processing and formulation factors on the production of spheres by extrusion and spheronisation. - Int. J. Pharm., 83, 187-196, 1992.
15. RIVERAS. L. and GHODBANE S. - In vitroadsorption-desorption of famotidine on microcrystalline cellulose. - Int. J. Pharm., 108, 31-38, 1994.
16. INDRAYANTO G., MUGIHARDJO, HANDAYANI R. - Compatibility study between famotidine and some excipients using differential scanning calorimetry. - Drug Dev. Ind. Pharm., 20, 911-920, 1994.
17. O' CONNER R.E. and SCHWARTZ J.B. - Extrusion and spheronization technology. - In : Pharmaceutical Pelletization Technology, I. Ghebre-Sellassie Ed., Marcel Dekker, Basel, 1989, pp. 207-214.
18. KLEINEBUDDE P. - Shrinking and swelling properties of pellets containing microcrystalline cellulose and low substituted hydroxypropylcellulose. II. Swelling properties. - Int. J. Pharm., 109, 221-227, 1994.
19. DAVIDSON R., EK R. and RAGNARSSON G - Determination of the expansion characteristics of porous cellulose matrices by image analysis. - Int. J. Pharm., 112, 153-163, 1994.