Detection of unknown mutations in DNA: A catch-22

American Journal of Human Genetics

Volumn 59, Issue 2, 1996, Pages 289-291

  Cotton, Richard G H ^a  

^a ST VINCENT S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER GENETICS; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA DETERMINATION; EDITORIAL; GEL ELECTROPHORESIS; GENE MUTATION; HUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

GENETIC DISEASES, INBORN; GENETIC SCREENING; MUTATION; SEQUENCE ANALYSIS, DNA;

EID: 0029790666     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (8)

1. Cotton R (1993) Current methods of mutation detection. Mutat Res 285:125-144
2. Grompe M (1993) The rapid detection of unknown mutations in nucleic acids. Nat Genet 5:11-117
3. Hansen LL, Justesen J, Kruse TA (1996) Sensitive and fast mutation detection by solid phase chemical cleavage. Hum Mutat 7:256-263
4. Phelps RS, Chadwick RB, Conrad MP, Kronick MM, Kamb A (1995) Efficient, automatic detection of heterozygous bases during large-scale DNA sequence screening. Biotechniques 19:984-989
5. Savov A, Angelicheva D, Balassopoulou A, Jordanova A, Noussia-Arvanitakis S, Kalaydjieva L (1995) Double mutant alleles: are they rare? Hum Mol Genet 4:1169-1171
6. Verpy E, Biasotto M, Brai M, Misiano G, Meo T, Tosi M (1996) Exhaustive mutation screening by fluorescence-assisted mismatch analysis discloses new genotype-phenotype correlations in angioedema. Am J Hum Genet 59:308-319 (in this issue)
7. Youil R, Kemper BW, Cotton RGH (1995) Screening for mutations by enzyme mismatch cleavage with T4 endonuclease VII. Proc Natl Acad Sci USA 92:87-91
8. (1996) Detection of 81 of 81 known mouse β-globin promoter mutations with T4 endonuclease VII-the EMC method. Genomics 32: 431-435