Formation of C1' located sugar radicals from X-irradiated cytosine nucleosides and -tides in BeF2 glasses and frozen aqueous solutions

International Journal of Radiation Biology

Volumn 70, Issue 3, 1996, Pages 327-336

  Weiland, B ^a   Huttermann J ^a   Malone, M E ^b   Cullis, P M ^b  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; FREE RADICAL; NUCLEOSIDE; NUCLEOTIDE;

AQUEOUS SOLUTION; ARTICLE; LOW TEMPERATURE; PRIORITY JOURNAL; X IRRADIATION;

CYTIDINE; CYTOSINE NUCLEOTIDES; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; FREEZING; SOLUTIONS; X-RAYS;

EID: 0029790532     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530096145067     Document Type: Article

References (21)

1. ALEXANDER, C. JR. and FRANKLIN, C. E., 1971, ESR study of the sugar radical in irradiated deoxyadenosine. The Journal of Chemical Physics, 54, 1909-13.
2. BARNES, J. and BERNHARD, W. A., 1991. One-electron-reduced cytosine in acidic glasses: conformational states before and after proton transfer. Journal of Physical Chemistry, 98, 887-93.
3. BARNES, J., BERNHARD, W. A. and MERCER, K. R., 1991, Distribution of electron trapping in DNA: protonation of one-electron reduced cytosine. Radiation Research, 126, 104-07.
4. BECKER, D., LA VERE, T. and SEVILLA, M. D., 1994, ESR detection at 77 K of the hydroxyl radical in the hydration layer of gamma-irradiated DNA. Radiation Research, 140, 123-9.
5. BERNHARD, W. A. and PATRZALEK, A. Z., 1989, ESR characteristics of one-electron reduced thymine in monomer, oligomer, and polymer derivatives. Radiation Research, 117, 379-94.
6. CULLIS, P. M., LANGMAN, S., PODMORE, I. D., and SYMONS, M. C. R., 1990, Effects of ionising radiation on deoxyribonucleic acid. Part VI.-Effects of hydroxyl scavengers on radition damage to DNA. Journal of the Chemical Society, Faraday Transactions, 86, 3267-71.
7. GRECOLI, S., OLASI, M. and BERTINCHAMPS, A., 1974, Free radicals in γ-irradiated frozen solutions of deoxyadenosine-5′-monophosphate. A computer analysis of temperature-dependent ESR spectra. Radiation Research, 60, 388-404.
8. GREGOLI, S., OLASI, M. and BERTINCHAMPS, A., 1977, Free radical formation in deoxyguanosine-5′-monophosphate γ-irradiated frozen solutions. A computer-assisted analysis of temperature-dependent ESR spectra. Radiation Research, 72, 201-17.
9. HÜTTERMANN, J., LANGE, M. and OHLMANN, J., 1992, Mechanistic aspects of radiation-induced free radical formation in frozen aqueous solution of DNA constituents: consequences for DNA? Radiation Research, 131, 18-23.
10. HÜTTERMANN, J., OHLMANN, J., SCHAEFER, A., GATZWEILER, W., 1991, The polymorphism of a cytosine anion studied by electron paramagnetic resonance spectroscopy. International Journal of Radiation Biology, 59, 1297-311.
11. LANGE, M., 1994, ESR-Untersuchungen und Strangbruch-Analysen der DNA und ihrer Untereinheiten nach Einwirkung dünn-ionisierender Strahlung in der gefrorenen, wäßrigen Lösung. Phd-thesis, Universität des Saarlandes (Germany).
12. LANGE, L., WEILAND, B., HÜTTERMANN, J., 1995, Influence of electron scavengers on the radical formation in thymidine-5′-monophosphate and DNA in frozen aqueous solution and glasses. International Journal of Radiation Biology, 68, 475-86.
13. MALONE, M. E., CULLIS, P. M., SYMONS, M. C. R. and PARKER, A. W., 1995, The biphotonic photoionisation of cytosine and its derivatives with UV radiation at 248 nm: an EPR study in low temperature perchlorate glasses. Journal of Physical Chemistry, 99, 9299-9308.
14. 2 glasses: an EPR study. International Journal of Radiation Biology, 63, 427-36.
15. RIEDERER, H., HÜTTERMANN, J., BOON, P. and SYMONS, M. C. R., 1983, Hydroxyl radicals in aqueous glasses: characterisation and reactivity studied by ESR spectroscopy. Journal of Magnetic Resonance, 54, 54-66.
16. SCHMIDT, J. and BORG, D. C., 1976, Free radicals from purine nucleotides after hydroxyl radical attack. Radiation Research, 65, 220-37.
17. SYMONS, M. C. R., 1989, ESR spectra for protonated thymine and cytidine radical anions: their relevance to irradiated DNA. International Journal of Radiation Biology, 58, 93-96.
18. SYMONS, M. C. R., 1991, The role of radiation induced charge migration with DNA: ESR studies. In: The Early Effects of Radiation on DNA. Edited by: E. M. Fielden and P. O'Neill NATO ASI Series H, 54 (Berlin: Springer Verlag), pp. 111-124.
19. WANG, W. and SEVILLA, M. D., 1994, Reaction of Cysteamine with individual DNA base radicals in γ-irradiated nucleotides at low temperature. International Journal of Radiation Biology, 66, 683-95.
20. WEILAND, B., 1994, ESR-Untersuchungen strahleninduzierter freier Radikale in DNA-Komponenten, DNA und Chromatin unter Einfluß von scavengern. Diploma thesis, Universität des Saarlandes (Germany).
21. VON SONNTAG, C, 1987, The Chemical Basis of Radiation Biology (London: Taylor&Francis).