CAP37, a neutrophil granule-derived protein stimulates protein kinase C activity in endothelial cells

Journal of Leukocyte Biology

Volumn 60, Issue 3, 1996, Pages 415-422

  Pereira, H Anne ^a,b   Moore, Pete ^a   Grammas, Paula ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Antimicrobial protein; Chemoattrac ant; Monocyte; Synthetic peptides

Indexed keywords

PHORBOL ESTER; PROTEIN CAP37; PROTEIN KINASE C; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0029790519     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.60.3.415     Document Type: Article

References (64)

1. Mantovani, A., Bussolino, F., Dejana, E. (1992) Cytokine regulation of endothelial cell function. FASEB J. 6, 2591-2599.
2. Key, N. S. (1992) Scratching the surface: endothelium as a regulator of thrombosis, fibrinolysis, and inflammation. J. Lab. Clin. Med. 120, 184-186.
3. Hart, M. N., Fabry, Z., Love-Homan, L., Keiner, J., Sadewasser, K. L., Moore, S. A. (1992) Brain microvascular smooth muscle and endothelial cells produce granulocyte macrophage colony-stimulating factor and support colony formation of granulocyte-macrophage-like cells. Am. J. Pathol. 141, 421-427.
4. Bevilacqua, M. P. (1993) Endothelial-leukocyte adhesion molecules. Annu. Rev. Immunol. 11, 767-804.
5. Granger, D. N., Kubes, P. (1994) The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion. J. Leukoc. Biol. 55, 662-675.
6. Brown, Z., Gerritsen, M. E., Carley, W. W., Strieter, R. M., Kunkel, S. L., Westwick, J. (1994) Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells. Am. J. Pathol. 145, 913-921.
7. Mantovani, A., Dejana, E. (1989) Cytokines as communication signals between leukocytes and endothelial cells. Immunol. Today 10, 370-375.
8. Pober, J. S., Cotran, R. S. (1991) What can be learned from the expression of endothelial adhesion molecules in tissues? Lab. Invest. 64, 301-305.
9. Gerritsen, M. E., Niedbala, M. J., Szczepanski, A., Carley, W. W. (1993) Cytokine activation of human macro- and microvessel-derived endothelial cells. Blood Cells 19, 325-342.
10. Zimmerman, G. A., Prescott, S. M., McIntyre, T. M. (1992) Endothelial cell interactions with granulocytes: tethering and signaling molecules. Immunol. Today 13, 93-99.
11. Westlin, W. F., Gimbrone, M. A., Jr. (1993) Neutrophil-mediated damage to human vascular endothelium. Am. J. Pathol. 142, 117-128.
12. Varani, J., Ginsburg, I., Schuger, L., Gibbs, D. F., Bromberg, J., Johnson, K. J., Ryan, U. S., Ward, P. A. (1989) Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases. Am. J. Pathol. 135, 435-438.
13. Savage, C. O. S., Pottinger, B. E., Gaskin, G., Pusey, C. D., Pearson, J. D. (1992) Autoantibodies developing to myeloperoxidase and proteinase 3 in systemic vasculitis stimulate neutrophil cytotoxicity toward cultured endothelial cells. Am. J. Pathol. 141, 335-342.
14. Streiter, R. M., Kasahara, K., Allen, R. M., Stanford, T. J., Rolfe, M. W., Becher, F. S., Chensue, S. W., Kunkel, S. L. (1992) Cytokine-induced neutrophil-derived interleukin-8. Am. J. Pathol. 141, 397-407.
15. Pereira, H. A. (1995) CAP37, a neutrophil-derived multifunctional inflammatory mediator. J. Leukoc. Biol. 57, 805-812.
16. Pereira, H. A., Shafer, W. M., Pohl, J., Martin, L. E., Spitznagel, J. K. (1990) CAP37 a human neutrophil-derived chemotactic factor with monocyte specific activity. J. Clin. Invest. 85, 1468-1476.
17. Pohl, J., Pereira, H. A., Martin, N. M., Spitznagel, J. K. (1990) Amino acid sequence of CAP37, a human neutrophil granule-derived antibacterial and monocyte-specific chemotactic glycoprotein structurally similar to neutrophil elastase. FEBS Lett. 272, 200-204.
18. Morgan, J. G., Sukiennicki, T., Pereira, H. A., Spitznagel, J. K., Guerra, M. E., Larrick, J. W. (1991) Cloning of the cDNA for the serine protease homolog CAP37/azurocidin, a microbicidal and chemotactic protein from human granulocytes. J. Immunol. 147, 3210-3214.
19. Almeida, R. P., Melchior, M., Campanelli, D., Nathan, C. F., Gabay, J. E. (1991) Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases. Biochem. Biophys. Res. Commun. 177, 688-695.
20. Pereira, H. A., Spitznagel, J. K., Pohl, J., Wilson, D. E., Morgan, J., Palings, I., Larrick, J. W. (1990) CAP37, a 37 IcD human neutrophil granule cationic protein shares homology with inflammatory proteinases. Life Sci. 46, 189-196.
21. Ostergaard, E., Flodgaard, H., (1992) A neutrophil-derived proteolytic inactive elaslase homologue (hHBP) mediates reversible contraction of fibroblasts and endothelial cell monolayers and stimulates monocyte survival and thrombospondin secretion. J. Leukoc. Biol. 51, 316-323.
22. Farago, A., Nishizuka, Y. (1990) Protein kinase C in transmembrane signalling. FEBS Leu. 268, 350-354.
23. Mattila, P. (1991) Protein kinase C subtypes in endothelial cells. FEBS Lett. 289, 86-90.
24. Mattila, P., Majuri, M.-L., Tiisala, S., Renkonen, R. (1994) Expression of six protein kinase C isolypes in endothelial cells. Life Sci. 55, 1253-1260.
25. Kiley, S. C., Jaken, S. (1994) Protein kinase C: interactions and consequences. Trends Cell. Biol. 4, 223-227.
26. Dekker, L. V., Parker, P. J. (1994) Protein kinase C - a question of specificity. Trends Biol. Sci. 19, 73-77.
27. Kishimoto, T., Taga, T., Akira, S. (1994) Cytokine signal transduction. Cell 76, 253-262.
28. Delomenie, C., Wautier-Pepin, M.-P., Chappey, O., Wautier, J.-L. (1993) Modulation of human endothelial cell activation by antiproliferative cytokines: exploration of arachidonic acid and intracellular cytokine pathways as possible mechanisms of action. Exp. Cell Res. 207, 122-130.
29. Renkonen, R., Mennander, A., Ustinov, J., Mattila, P. (1990) Activation of protein kinase C is crucial in the regulation of ICAM-1 expression on endothelial cells by interferon-γ. Int. Inmunol. 2, 719-724.
30. Bereta, J., Bereta, M., Cohen, S., Cohen, M. C. (1991) Studies on the role of protein kinases in the TNF-mediated enhancement of mutine tumor cell-endothelial cell interactions. J. Cell. Biochem. 47, 62-78.
31. Mattila, P., Häyry, P., Renkonen, R. (1990) Protein kinase C is crucial in signal transduction during interferon-gamma induction in endothelial cells. Transplant. Proc. 22, 130.
32. Magnuson, D. K., Maier, R. V., Pohlman, T. H. (1989) Protein kinase C: a potential pathway of endothelial cell activation by endotoxin, tumor necrosis factor, and interleukin-1. Surgery 106, 216-223.
33. Deisher, T. A., Haddix, T. L., Montgomery, K. F., Pohlman, T. H., Kaushansky, K., Harlan, J. M. (1993) The role of protein kinase C in the induction of VCAM-1 expression on human umbilical vein endothelial cells. FEBS. Lett. 331, 285-290.
34. Rush, J. S., Waechler, C, J. (1987) Inhibitors of protein kinase C block activation of B lymphocytes by bacterial lipopolysaccharide. Biochem. Biophys. Res. Commun. 145, 1315-1320.
35. Ritchie, A. J., Johnson, D. R., Ewenstein, B. M., Pober, J. S. (1991) Tumor necrosis factor induction of endothelial cell surface antigens is independent of protein kinase C activation or inactivation. J. Immunol. 146, 3056-3062.
36. Shafer, W. M., Martin, L. E., Spitznagel, J. K. (1984) Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate. Infect. Immun. 45, 29-35.
37. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.) 227, 680-685.
38. Pereira, H. A., Erdem, I., Pohl, J., Spitznagel, J. K. (1993) Synthetic bactericidal peptide based on CAP37: a 37-kDa human neutrophil granule-associated cationic antimicrobial protein chemotactic for monocytes. Proc. Natl. Acad. Sci. USA 90, 4733-4737.
39. Pereira, H. A., Martin, L. E., Spitznagel, J. K. (1989) Quantitation of a cationic antimicrobial granule protein of human polymorphonuclear leukocytes by ELISA. J. Immunol. Meth. 117, 115-120.
40. Diglio, C. A., Liu, W., Grammas, P., Giacomelli, F., Wiener, J. (1993) Isolation and characterization of cerebral resistance vessel endothelium in culture. Tissue Cell 25, 833-846.
41. Hanson-Painton, O., Morgenstern, K., Cooper, D. R., Moore, B., Botchlet, T., Grammas, P. (1993) Protein kinase C in rat cerebral microvessels. Mol. Chem. Neuropathol. 20, 245-261.
42. Grammas, P., Moore, P., Botchlet, T., Hanson-Painton, O., Cooper, D. R., Ball, M. J., Roher, A. (1995) Cerebral microvessels in Alzheimer's have reduced protein kinase C activity. Neurobiol. Aging 16, 563-569.
43. Newton, A. C. (1995) Protein kinase C: Structure, function and regulation. J. Biol. Chem. 270, 28495-28498.
44. Ben-Baruch, A., Michiel, D. F., Oppenheim, J. J. (1995) Signals and receptors involved in recruitment of inflammatory cells. J. Biol. Chem. 270, 11703-11706.
45. Shyy, Y.-J., Li, Y.-S., Kolattukudy, P. E. (1993) Activation of MCP-1 gene expression is mediated through multiple signaling pathways. Biochem. Biophys. Res. Commun. 192, 693-699.
46. Müllberg, J., Schooltink, H., Stoyan, T., Heinrich, P. C., Rose-John, S. (1992) Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor. Biochem. Biophys. Res. Commun. 189, 794-800.
47. Katabami, T., Shimizu, M., Okano, K., Yano, Y., Nemoto, K., Ogura, M., Tsukamoto, T., Suzuki, S., Ohira, K., Yamada, Y., Sekita, N., Yoshida, A., Someya, K. (1992) Intracellular signal transduction for interleukin-1β-induced endothelin production in human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 188, 565-570.
48. Nishizuka, Y. (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258, 607-614.
49. Nishizuka, Y. (1995) Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 9, 484-496.
50. Kelvin, D. J., Michiel, D. F., Johnston, J. A., Lloyd, A. R., Sprenger, H., Oppenheim, J. J., Wang, J. M. (1993) Chemokines and serpentines: the molecular biology of chemokine receptors. J. Leukoc. Biol. 54, 604-612.
51. Henson, P. M., Doherty, D. E., Riches, D. W. H., Parsons, P. E., Worthen, C. S. (1994) LPS and cytokines in lung injury. In Endotoxin and the Lungs (K. L. Brigham, ed.) New York, Marcel Dekker, 267-304.
52. Flodgaard, H., Ostergaard, E., Bayne, S., Svendsen, A., Thomsen, J., Engels, M., Wollmer, A. (1991) Covalent structure of two novel neutrophil leucocyte-derived proteins of porcine and human origin. Eur. J. Biochem. 197, 535-547.
53. Hurley, J. V. (1983) Acute Inflammation, 2nd ed., Edinburgh, Churchill Livingstone, 109-117.
54. Wilkinson, P. C. (1982) Chemotaxis and Inflammation, 2nd ed., Edinburgh, Churchill Livingstone, 119-142.
55. Spitznagel, J. K. (1990) Antibiotic proteins of human neutrophils. J. Clin. Invest. 86, 1381-1386.
56. Lehrer, R. I., Ganz, T., Selsted, M. E. (1991) Defensins: endogenous antibiotic peptides of animal cells. Cell 64, 229-230.
57. Farley, D., Salvesen, G., Travis, J. (1988) Molecular cloning of human neutrophil elastase. Biol. Chem. Hoppe Seyler 369, 3-7.
58. Campanelli, D., Detmers, P. A., Nathan, C. F., Gabay, J. E. (1990) Azurocidin and a homologous serine protease from neutrophils: differential antimicrobial and proteolytic properties. J. Clin. Invest. 85, 904-915.
59. Shafer, W. M., Pohl, J., Onunka, V. C., Bangalore, N., Travis, J. (1991) Human lysosomal cathepsin G and granzyme B share a functionally conserved broad spectrum antibacterial peptide. J. Biol. Chem. 266, 112-116.
60. Elsbach, P., Weiss, J. (1993) The bactericidal/permeabitity-increasing protein (BPI), a potent element in host-defense against gram-negative bacteria and lipopolysaccharide. Immunobiol. 187, 417-429.
61. Pereira, H. A., Spitznagel, J. K., Winsion, E. F., Shafer, W. M., Martin, L. E., Guzman, G. S., Pohl, J., Scott, R. W., Marra, M. N., Kinkade, J. M., Jr. (1990) The ontogeny of a 57-Kd cationic antimicrobial protein of human polymorphonuclear leukocytes: localization to a novel granule population. Blood 76, 825-834.
62. Gray, B. H., Haseman, J. R. (1994) Bactericidal activity of synthetic peptides based on the structure of the 55-kilodalton bactericidal protein from human neutrophils. Infect. Immun. 62, 2732-2739.
63. Charp, P. A., Rice, W. G., Raynor, R. L., Reimund, E., Kinkade, J. M., Jr., Ganz, T., Selsted, M. E., Lehrer, R. I., Kuo, J. F. (1988) Inhibition of protein kinase C by defensins, antibiotic peptides from human neutrophils. Biochem. Pharmacol. 37, 951-956.
64. Weksler, B. B., Jaffe, E. A., Brower, M. S., Cole, O. F. (1989) Human leukocyte cathepsin G and elastase specifically suppress thrombin-induced prostacyclin production in human endothelial cells. Blood 74, 1627-1634.