Immune dominant auto-epitopes;Immundominante Autoepitope

Deutsche Medizinische Wochenschrift

Volumn 121, Issue 41, 1996, Pages 1267-1270

  Dorner T ^a,b   Hiepe, F ^a,c   Burmester, G R ^a,c  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; EPITOPE; BACTERIAL ANTIGEN;

ANTIBODY RESPONSE; AUTOIMMUNITY; ETIOLOGY; HUMAN; INFECTION; SHORT SURVEY; ANIMAL; AUTOIMMUNE DISEASE; BIOSYNTHESIS; IMMUNOLOGY; MOLECULAR MIMICRY; REVIEW;

ANIMALS; ANTIGENS, BACTERIAL; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; HUMANS; IMMUNODOMINANT EPITOPES; MOLECULAR MIMICRY;

EID: 0029790380     PISSN: 00120472     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1043138     Document Type: Short Survey

References (18)

1. Ahmed, R., D. Gray: Immunological memory and protective immunity: Understanding their relation. Science 272 (1996), 54-60.
2. Chan, E. K., J. C. Hamel, J. P. Buyon, E. M. Tan: Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J. clin. Invest. 87 (1991), 68-78.
3. Christian, C. L.: Role of viruses in etiology of systemic lupus erythematosus. Amer. J. Kidney Dis. 2 (1982), 114-118.
4. Datta, S. K., R. S. Schwartz: Genetics of expression of xenotropic virus and autoimmunity in NZB mice. Nature (Lond.) 263 (1976), 412-415.
5. Dörner, T., E. Feist, A. Wagenmann, T. Kato, K. Yamamoto, K. Nishioka, G. R. Burmester, F. Hiepe: Anti-52 kD (Ro(SS-A) autoantibodies occuring in different autoimmune diseases preferentially recognize B-cell epitopes present on the central region of the antigen. J. Rheumatol. 23 (1996), 462-469.
6. Huang, S. C., Z. Pan, B. T. Kurien, J. A. James, J. B. Harley, R. H. Scofield: Immunization with vesicular stomatitis virus nucleocapsid protein induces autoantibodies to the 60 kD Ro ribonucleoprotein particle. J. invest. Med. 43 (1995), 151-158.
7. Itoh, K., Y. Itoh, M. B. Frank: Protein heterogeneity in the human Ro/SSA ribonucleoproteins. The 52- and 60-kD Ro/SSA autoantigens are encoded by separate genes. J. clin. Invest. 87 (1991), 177-186.
8. James, J. A., T. Gross, R. H. Scofield, J. B. Harley: Immunoglobulin epitope spreading and autoimmune disease after peptide immunization. Sm B/B′-derived PPPGMRPP and PPPGIRGP induce splicosome autoimmunity. J. exp. Med. 181 (1995), 453-461.
9. Kalden, J. R., S. Gay: Retroviruses and autoimmune rheumatic diseases. Clin. exp. Immunol. 98 (1994), 1-5.
10. Kato, T., K. Yamamoto, H. Takeuchi, M. Okubo, E. Hara, S. Nakada, K. Oda, K. Ito, K. Nishioka: Identification of a universal B cell epitope on DNA topoisomerase 1, an autoantigen associated with scleroderma. Arthr. and Rheum. 36 (1993), 1580-1587.
11. Kohsaka, H., K. Yamamoto, H. Fuji, H. Miura, N. Miyasaka, K. Nishioka, T. Miyamoto: Fine epitope mapping of the human SS-B/1a protein. Identification of a distinct autoepitope homologous to a viral gag protein. J. clin. Invest. 85 (1990), 1566-1574.
12. Lanzavecchia, A.: Antigen-specific interaction between T and B cells. Nature (Lond.) 314 (1985), 537-539.
13. McNeilage, L.J., E. MaacMillan, S. F. Whittingham: Mapping of epitopes on the La(SS-B) autoantigen of primary Sjögren's syndrome. Identification of a cross-reactive epitope. J. Immunol. 145 (1990), 3820-3835.
14. Ray, S. K., C. Putterman, B. Diamond: Pathogenic autoantibodies are routinely generated during the response to foreign antigen. A paradigm for autoimmune disease. Proc. nat. Acad. Sci. (Wash.) 93 (1996), 2019-2024.
15. Scofield, H., J. B. Harley: Autoantigenicity of Ro/SS-A antigen is related to a nucleocapsid protein of vesicular stomatitis virus. Proc. nat. Acad. Sci. (Wash.) 88 (1991), 3343-3347.
16. Talal, N., R. F. Garry, P. H. Schur: A conserved idiotype and antibodies to retroviral proteins in systemic lupus erythematosus. J. clin. Invest. 85 (1990), 1866-1871.
17. Tan, E. M.: Antinuclear antibodies. Diagnostic markers for autoimmune diseases and probes for cell biology. Advanc. Immunol. 44 (1989), 93-151.
18. Wahren, M., U. Rudén, B. Andersson, N. R. Ringertz, I. Petterson: Identification of antigenic regions of the human Ro 60 kDa protein using recombinant antigen and synthetic peptides. J. Autoimmunity 5 (1992), 319-332.