Presence of pancreatitis-associated protein in pancreatic acinar cells of rats treated with chlorophenylalanine methyl ester

Pancreas

Volumn 13, Issue 2, 1996, Pages 147-153

  Chen, Ping ^a   Arias, Ariel E ^a   Morisset, Jean ^b   Calvo, Ezequiel ^b   Dagorn, Jean Charles ^c   Iovanna, Juan ^c   Bendayan, Moïse ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DE SHERBROOKE   (Canada)

^c INSERM   (France)

Author keywords

Acinar cell; Chlorophenylalanine methyl ester; Pancreas; Pancreatitis associated protein; Secretory granules

Indexed keywords

FENCLONINE METHYL ESTER; PANCREAS ASSOCIATED PROTEIN; SECRETORY PROTEIN; UNCLASSIFIED DRUG;

ACUTE PANCREATITIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; IMMUNOCYTOCHEMISTRY; NONHUMAN; NORTHERN BLOTTING; PANCREAS ACINUS; PANCREAS INJURY; PRIORITY JOURNAL; RAT; SECRETORY GRANULE;

EID: 0029789785     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-199608000-00005     Document Type: Article

References (37)

1. Keim V, Rohr G, Stockert HG, Haberich FJ. An additional secretory protein in the rat pancreas. Digestion 1984;29: 242-9.
2. Keim V, Iovanna JL, Rohr G, Usadel KH, Dagorn JC. Purification and partial characterization of a rat pancreatic secretory protein associated with acute pancreatitis. Gastroenterology 1991;100:775-81.
3. Iovanna JL, Keim V, Bosshard A, et al. PAP, a pancreatic secretory protein induced during acute pancreatitis, is expressed in rat intestine. Am J Physiol 1993;265:G611-8.
4. Keim V, Iovanna JL, Orelle V, et al. A novel exocrine protein associated with pancreas transplantation in humans. Gastroenterology 1992;103:248-54.
5. Keim V, Fuchs MJ, Baum B, Lang S, Iovanna JL, Dagorn JC. Fragments of the PAP (pancreatitis-associated protein) in serum and urine of patients with acute pancreatitis. Pancreas 1992;7:563.
6. Keim V, Willemer S, Iovonna JL, Adler G, Dagorn JC. Rat pancreatitis-associated protein is expressed in relation to severity of experimental pancreatitis. Pancreas 1994;9:606-12.
7. Iovanna JL, Férec C, Sarles J, Dagorn JC. The pancreatitis-associated protein (PAP). A new candidate for neonatal screening of cystic fibrosis. CR Acad Sci Paris 1994;317: 561-4.
8. Iovanna JL, Orelle B, Keim V, Dagorn JC. Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis. J Biol Chem 1991;266:24664-9.
9. Keim V, Iovanna JL, Dagorn JC. The acute phase reaction of the exocrine pancreas. Digestion 1994;55:65-72.
10. Keim V, Löffler HG. Pancreatitis-associated protein in bile acid-induced pancreatitis of the rat. Clin Physiol Biochem 1986;4:136-42.
11. Arias AE, Bendayan M. Intracisternal crystals in pancreatic acinar cells: failure in the distinct aggregation of secretory proteins. Eur J Cell Biol 1993;62:282-93.
12. Velez-Granell CS, Arias AE, Torres-Ruíz JA, Bendayan M. Molecular chaperones in pancreatic tissue: the presence of cpn10, cpn60 and hsp70 in distinct compartments along the secretory pathway of the acinar cells. J Cell Sci 1994;107: 539-49.
13. Arias AE, Velez-Granell CS, Torres-Ruíz JA, Bendayan M. Involvement of molecular chaperones in the aberrant aggregation of secretory proteins in pancreatic acinar cells. Exp Cell Res 1994;215:1-8.
14. Bendayan M. Protein A-gold electron microscopic immunocytochemistry: methods, applications and limitations. J Electron Microsc Tech 1984;1:243-70.
15. Bendayan M. Colloidal gold post-embedding immunocytochemistry. Prog Histochem Cytochem 1995;29:1-162.
16. Chirgwin JM, Prizbyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979;18:5294-9.
17. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning, a laboratory manual, 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
18. Arias AE, Bendayan M. Secretagogue induction of cell differentiation in pancreatic acinar cells in vitro. Exp Cell Res 1991;195:199-206.
19. Kopriwa BM, Leblond CP. Improvements in the coating technique of radioautography. J Histochem Cytochem 1962; 10:269-84.
20. Paiement J, Dominguez JM, Guénette A, Roy L. GTP-dependent membrane fusion during hepatocarcinogenesis and liver regeneration. Biochem Biophys Res Commun 1991; 176:1494-500.
21. Williams MA. The assessment of electron microscope autoradiographs. Adv Opt Electron Microsc 1969;3:219-72.
22. Baker JRJ. Autoradiography: a comprehensive overview. New York: Oxford University Press, 1989.
23. Tooze J, Kern HF, Fuller SD, Howell KE. Condensation-sorting events in the rough endoplasmic reticulum of exocrine pancreatic cells. J Cell Biol 1989;109:35-50.
24. Forssmann WG, Bierger W. Biosynthese falscher Proteine: Einbau von p-Chlorphenylalanin in Enzyme des exokrinen Pankreas. Res Exp Med 1973;160:1-20.
25. Nadelhaft I. Measurement of the size distribution of zymogen granules from rat pancreas. Biophys J 1973;13:1014-29.
26. Liebow C, Rothman SS. Distribution of zymogen granule size. Am J Physiol 1973;225:258-62.
27. Sato M, Take H. Quantitative analysis of secretory granules of the pancreatic acinar cell of the rat. J Electron Microsc 1975;24:190.
28. Beaudoin AR, Grondin G, Filion M, Lord A. Secretagogues cause a preferential discharge of large size granules in rat pancreas. Can J Biochem Cell Biol 1984;62:1288-92.
29. Aughsteen AA, Cope GH. Changes in the size and number of secretion granules in the rat exocrine pancreas induced by feeding or stimulation in vitro. A morphometric study. Cell Tissue Res 1987;249:427-36.
30. Ermak TH, Rothman SS. Zymogen granules of pancreas decrease in size in response to feeding. Cell Tissue Res 1981; 214:51-66.
31. Beaudoin AR, Grondin G. Pathways of secretion in the exocrine pancreas: the status of resting secretion. Life Sci 1987; 40:2453-60.
32. Beaudoin AR, Grondin G. Zymogen granules of the pancreas and the parotid gland and their role in cell secretion. Int Rev Cytol 1992;132:177-221.
33. Grondin G, Iovanna J, Dagorn J-C, Morisset J. A typical ultrastructural and immunocytochemical localization of pancreatitis associated protein (PAP) after pancreatitis induction in rats. ICEM Paris 1994;13:1245-6.
34. Tooze SA, Flatmark T, Tooze J, Huttner WB. Characterization of the immature secretory granule, an intermediate in granule biogenesis. J Cell Biol 1991;15:1491-503.
35. Rhodes CJ, Halban PA. Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated rather than a constitutive pathway. J Cell Biol 1987;105:145-53.
36. Roberge M, Beaudoin AR. Newly synthesized secretory proteins from pig pancreas are not released from a homogeneous granule compartment. Biochim Biophys Acta 1982; 716:331-6.
37. Beaudoin AR, Vachereau A, St-Jean P. Evidence that amylase is released from two distinct pools of secretory proteins in the pancreas. Biochim Biophys Acta 1983;757:302-5.