Efficacy and safety of cetirizine in allergic diseases. Results of a multicenter study in 1,251 patients;Wirksamkeit und Sicherheit von Cetirizin bei allergischen Erkrankungen. Ergebnisse einer Studie an 1,251 Patienten

Allergologie

Volumn 19, Issue 10, 1996, Pages 473-478

  Popp, W ^a,b   Farr, Ch ^a  

^a Inst Atemwegs Lungenerkrankungen   (Austria)

^b NONE   (Austria)

Author keywords

asthma; cetirizine; clinical effects; efficacy; seasonal allergic rhinitis; tolerability; urticaria

Indexed keywords

CETIRIZINE;

ADOLESCENT; ADULT; AGED; ALLERGIC RHINITIS; ARTICLE; ASTHMA; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; GASTROINTESTINAL DISEASE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; SLEEP DISORDER; URTICARIA;

EID: 0029788664     PISSN: 03445062     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Bousquet J., A. Emonot, J. Germouty et al.: Double-blind multicenter study of cetirizine in grass-pollen-induced asthma. Ann. Allergy 65, 504-508 (1990).
2. Ciprandi G., S. Buscaglia, G. Pesce, G. Passalacqua, J.P. Rihoux, M. Bagnasco, G. W. Canonica. Cetirizine reduces inflammatory cell recruitment and ICAM-1 (or CD 54) expression on conjunctival epithelium in both early and late-phase reactions after allergen-specific challenge. J. Allergy Clin. Immunol. 95, 612-621 (1995).
3. Charlesworth E.N, A. Kagey-Sobotka, P.S. Norman, L.M. Lichtenstein: Effect of cetirizine on mast cell-mediator release and cellular traffic during the cutaneous, late-phase reaction. J. Allergy Clin. Immunol. 83, 905-912 (1969).
4. Coulie P.J., L. Ghys, J.P. Rihoux: Histamine-induced wheat, flare and pruritus; inhibition by cetirizine, terfenadine and placebo. Drug Dev. Res. 23, 269-274 (1991).
5. De Vos C., L. Michel, L. Dubertret et al.: Correlation between in vivo and in vitro properties of cetirizine 2HCl eosinophil recruitment and chemotaxis in man. Allergy 43 (Suppl. 7) (1988).
6. De Vos C. et al.: Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetrizine. Int. Arch. All. & Appl. Immunol. 88, 212-215 (1989).
7. Dijkman J.H., P.R.M. Hekking, J.F. Molkenboer et al.: Prophylactic treatment of grass pollen-induced asthma with cetirizine. Clin. Exp. Allergy 20, 483-490 (1990).
8. Fadel R. et al.: Inhibition of cetirizine 2HCl of antigen-induced eosinophil migration in allergic subjects. Health Sci. Rev. 3, 11-13 (1989).
9. Falliers C.J., M.L. Brandon, E. Buchman, J.T. Connell. R. Dockhorn, P.T. Leese, J. Miller, S.I. Wasserman, J.M. Zeterberg, R. Altman, S. Love, L.L. Samuels: Double-blind comparison of cetirizine and placebo in the treatment of seasonal rhinitis. Ann. Allergy 66, 257-262 (1991).
10. Grant J.A., C.F. Nikodomus, S.R. Findlay, M.M. Glovsky, J. Grossman, H. Kaiser, E.O. Meltzer, D.O. Mitchell, D. Peartman, J. Seiner, G. Settipane, W. Silvers: Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective randomized placebo-controlled trial. J. Allergy Clin. Immunol. 95, 923-932 (1995).
11. Juhlin L., C. Arendt: Treatment of chronic urticaria with cetirizine dihydrochloride, a non-sedating antihistamine. Brit. J. Derm. 119, 67-72 (1988).
12. Kalivas J. et al.: Placebo-controlled comparison of cetirizine and hydroxyzine in chronic urticaria. Meet. Amer. Acad. Dermat., 4.-7. Dezember 1988, Washington D.C.
13. Mansman H.C. Jr., R.A. Altman, B.A. Bermman, E. Buchman, R.J. Dockhorn, P.T. Leese, S.J. Love, E. Middleton Jr.: Efficacy and safety of cetirizine therapy in perennial allergic rhinitis. Ann. Allergy 68, 348-359 (1992).
14. Michel L., F. Jean-Louis, C. Burtin: Measurement of cetirizine effects on protein diffusion, mediator release and eosinophil recruitment during in vivo anaphylactic cutaneous reactions. Health Sci. Rev. 3, 14-17 (1969).
15. Poirrier R.: Lack of central nervous system effects with cetirizine. Health Science Rev. 3, 6-11 (1989).
16. Redier H., P. Chanez, C. Devos, N. Rifai, A.M. Clauzel, F.B. Michel, P.H. Godard: Inhibitory effect of cetirizine on the bronchial eosinophil recruitment induced by allergen inhalation challenge in allergic patients with asthma. J. Allergy Clin. Immunol. 90, 215-224 (1992).
17. Seedel W.F., S. Cohen, N.G. Bliwise, W.C. Dement: Cetirizine effects on objective measures of daytime sleepiness and performance. Ann. Allergy 59, 58-62 (1987).
18. Simons F.E.R., J.L. McMillan, K.J. Simons: A double-blind, single-dose, crossover comparison of cetirizine. tertenadine, loratadine, astemizole and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects. J. Allergy Clin. Immunol. 86, 540-547 (1990).
19. Simons F.E.R.. K.J. Simons, T.G. Fraser, J.D. Reggin: Comparison of the central nervous system (CNS) effects and peripheral H1-blockade produced by six H1-receptor antagonists. J. Allergy Clin. Immunol. abstr. 454, 254 (1995).
20. Snowman A.M., S.H. Snyder: Cetirizine: actions on neurotransmitter receptors J. Allergy Clin. Immunol. 86, 1025-1028 (1990).
21. Snyman J.R., K. De Sommers, M. Van Wyk, D.J. Lizamore: Effects of longterm cetirizine treatment of the cutaneous hypersensivity reaction in patients with grass pollen allergy. Eur. J. Clin. Pharmacol. 46, 19-22 (1994).
22. Spyropoulou-Vlahou M., A. Stravropoulos-Giokas, M. Filippou, A. Koyas, K. Kontou-Fili: Clinical and laboratory results confirm the efficacy of cetirizine 2HCl in seasonal allergic rhinitis. Acta Therapeutics 16, 71-78 (1990).
23. Volkerts E.R., A.P.P. Van Willigenburg, M. W. Van Laar und R.A.A. Maes: Does cetirizine belong to the new generation of antihistamines? An investigation into the acute and subchronic effects on highway driving, psychometric test performance and day time sleepiness. Human Psychopharmacology 7, 227-238 (1992).
24. Zimmermann T.H.: Einsatz von Cetirizin bei Kindern mit allergischen Erkrankungen. Allergo J. 2, 47-52 (1993).