Amphotericin B lipid complex: Review of safety, pharmacokinetics and efficacy

Drugs of Today

Volumn 32, Issue 5, 1996, Pages 411-416

  Dix, Suzanne P ^a   Wingard, John R ^b  

^a EMORY UNIVERSITY HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX;

ASPERGILLOSIS; CANDIDIASIS; DRUG EFFICACY; DRUG METABOLISM; DRUG SAFETY; HUMAN; MENINGITIS; MYCOSIS; NEPHROTOXICITY; NONHUMAN; REVIEW;

EID: 0029788506     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.1996.32.5.379050     Document Type: Review

References (19)

1. Saral, R. Candida and aspergillus infections in immunocompromised patients: An overview. J Infect Dis 1991, 13: 487-92.
2. Data on file. The Liposome Company, Inc., 1996.
3. Clark, J.M., Whitney, R.R., Olsen, S.J. et al. Amphotericin B lipid complex therapy of experimental fungal infections in mice. Antimicrob Agents Chemother 1991, 35: 615-21.
4. Clemons, K.V., Stevens, D.A. Comparative efficacies of amphotericin lipid B complex and amphotericin B deoxycholate suspension against murine blastomycosis. Antimicrob Agents Chemother 1991, 35: 2144-6.
5. Allendorfer, R., Yates, R.R., Sun, S.H., Graybill, J.R. Comparison of amphotericin B lipid complex with amphotericin B and SCH 39304 in the treatment of murine coccidioidal meningitis. J Med Vet Mycol 1992, 30: 377-84.
6. Lee, J., Anende, M., Amantea, M. et al. Pharmacokinetics and efficacy of amphotericin B lipid complex (ABLC) against chronic disseminated candidiasis in rabbits. 31st Intersci Conf Antimicrob Agents Chemother (Sept 29-Oct 2, Chicago) 1991, Abst 579.
7. Crasela, D., Echevarria, J., Summerill, R. et al. Pharmacokinetics of amphotericin B following administration as amphotericin B lipid complex (ABLC) or Fungizone (FZ) in adults with mucocutaneous leishmaniasis. 33rd Intersci Conf Antimicrob Agents Chemother (Oct 17-20, New Orleans) 1993, Abst 172.
8. Kan, V.L., Bennet, J.E., Amantea, M.A. et al. Comparative safety, tolerance, and pharmacokinetics of amphotericin B lipid complex and amphotericin B deoxycholate in healthy male volunteers. J Infect Dis 1991, 164: 418-21.
9. Hiemenz, J.W., Lister, J., Anaissie, E.J. et al. Emergency-use amphotericin B lipid complex (ABLC) in the treatment of patients with aspergillosis: Historical-control comparison with amphotericin B. Blood 1995, 86: Abst 3383.
10. Anaissie, E.J., White, M.H., Uzun, O. et al. Treatment of invasive candidiasis: A randomized, multicenter trial comparing amphotericin B lipid complex to amphotericin B. In press.
11. Sharkey, P.K., Graybill, J.R., Johnson, E.S. et al. Amphotericin B lipid complex compared with amphotericin B in the treatment of cryptococcal meningitis in patients with AIDS. Clin Infect Dis 1996, 22: 315-21.
12. Sharkey, P.K., Lipke, R., Renteris, A. et al. Amphotericin B lipid complex (ABLC) in treatment of coccidioidomycosis. 31 st Intersci Conf Antimicrob Agents Chemother (Sept 29-Oct 2, Chicago) 1991, Abst 742.
13. Anaissie, E.J., Ramphal, R. Efficacy and safety of amphotericin B lipid complex (ABLC) in the treatment of patients with life-threatening fusariosis. 34th Intersci Conf Antimicrob Agents Chemother (Oct 4-7, Orlando) 1994, Abst M87.
14. Jones, R.S., Barman, A., Suh, B., Heifets, M., Bocobo, F.C. Amphotericin B lipid complex treatment of Aspergillus osteomyelitis in a renal transplant patient 31st Annu Meet Infect Dis Soc (Oct 16-18, New Orleans) 1993, Abst.
15. Kline, M.W., Bocobo, F.C., Paul, M.E., Rosenblatt, H.M., Shearer, W.T. Successful medical therapy of Aspergillus osteomyelitis of the spine in an 11-year-old boy with chronic granulomatous disease. Pediatrics 1994, 93: 830-5.
16. Hospenthal, D.R., Byrd, J.C., Weiss, R.B. Successful treatment of invasive aspergillosis complicating prolonged treatment-related neutropenia in acute myelogenous leukemia with amphotericin B lipid complex. Med Ped Oncol 1995, 25: 119-22.
17. Mehta, J., Kelsey, S.M., Chu, P. et al. Amphotericin B lipid complex (ABLC) for fungal sepsis in immunocompromised patients. Blood 1995, 86: Abst 2042.
18. Oravcova, E., Mistrik, M., Sakalova, A. et al. Amphotericin B lipid complex to treat invasive fungal infections in cancer patients: Report of efficacy and safety in 20 patients. Chemotherapy 1995, 41: 473-6.
19. Wingard, J.R., Walker, R.S. Efficacy of amphotericin B lipid complex in the treatment of bone marrow transplant recipients with life-threatening systemic mycoses. Blood 1994, 84: Abst 1928.