Are cytochrome P450 3A enzymes in the small intestine responsible for different cyclosporine metabolite patterns in stable male and female renal allograft recipients after co-administration of diltiazem?

Transplantation Proceedings

Volumn 28, Issue 4, 1996, Pages 2159-2161

  Christians, U ^a   Bleck, J S ^a   Lampen, A ^a   Bader, A ^a   Thiesemann, C ^a   Kliem, V ^a   Repp, H ^a   Westhoff Bleck, M ^a   Manns, M ^a   Sewing, K F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CYCLOSPORIN A; CYTOCHROME P450; DILTIAZEM; ENZYME INHIBITOR; IMMUNOSUPPRESSIVE AGENT;

ADULT; CLINICAL ARTICLE; CLINICAL TRIAL; COMPETITIVE INHIBITION; CONFERENCE PAPER; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG METABOLISM; EMULSION; ENZYME ACTIVITY; FEMALE; GRAFT REJECTION; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE EPITHELIUM CELL; KIDNEY ALLOGRAFT; KIDNEY TRANSPLANTATION; MALE; NEPHROTOXICITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SMALL INTESTINE;

ADOLESCENT; ADULT; AGED; CALCIUM CHANNEL BLOCKERS; CYCLOSPORINE; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DILTIAZEM; DUODENUM; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTESTINAL MUCOSA; KIDNEY TRANSPLANTATION; MALE; METABOLIC CLEARANCE RATE; MICROSOMES; MIDDLE AGED; MIXED FUNCTION OXYGENASES; SEX CHARACTERISTICS;

EID: 0029788148     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (0)