Pregnancy enhances cocaine-induced stimulation of uterine contractions in the chronically instrumented rat

American Journal of Obstetrics and Gynecology

Volumn 175, Issue 1, 1996, Pages 188-193

  Nakahara, K ^a   Iso, A ^a   Chao, C R ^a   Cooper, T B ^a   Morishima, H O ^a  

^a PH Box 9   (United States)

Author keywords

Cocaine; pregnancy; rat; uterine activity

Indexed keywords

BENZOYLECGONINE; COCAINE; OXYTOCIN; SODIUM CHLORIDE;

ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; DRUG ABUSE; DRUG EFFECT; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PREGNANCY; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; UTERUS CONTRACTILITY;

EID: 0029787541     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(96)70273-9     Document Type: Article

References (24)

1. SN MacGregor LG Keith IJ Chasnoff MA Rosner GM Chisum P Shaw Cocaine use during pregnancy: adverse perinatal outcome Am J Obstet Gynecol 157 1987 686 690
2. IJ Chasnoff DE Lewis DR Griffith S Willey Cocaine and pregnancy: clinical and toxicological implications for the neonate Clin Chem 35 1989 1276 1278
3. IJ Chasnoff WJ Burns SH Schnoll KA Burns Cocaine use in pregnancy N Engl J Med 313 1985 666 669
4. A Handler N Kistin F Davis Cocaine use during pregnancy: perinatal outcomes Am J Epidemiol 133 1991 818 825
5. EM Ostrea M Grady S Gause Drug screening of newborns by meconium analysis: a large scale, perspective, epidemiologic study Pediatrics 89 1992 107 113
6. M Monga NW Weisbrodt RL Andres BM Sanborn Cocaine acutely increases rat myometrial contractile activity by mechanisms other than potentiation of adrenergic pathways Am J Obstet Gynecol 169 1993 1502 1506
7. MH Abel M Hollingsworth The potencies and selectivities of four calcium antagonists as inhibitors of uterine contractions in the rat in vivo Br J Pharmacol 85 1985 263 269
8. S Ikeda H Tamaoki M Akahane Y Nebashi Effects of ritodrine hydrochloride, a beta 2-adrenoceptor stimulant, on uterine motilities in late pregnancy Jpn J Pharmacol 35 1984 319 326
9. R Caldeyro-Barcia Y Sica-Blanco JJ Poseiro VG Panizza C Mendez-Bauer C Fielitz A quantitative study of the action of synthetic oxytocin on the pregnant human uterus J Pharmacol Exp Ther 121 1957 18 31
10. JJ Hirst GJ Haluska MJ Cook DL Hess MJ Novy Comparison of plasma oxytocin and catecholamine concentrations with uterine activity in pregnant rhesus monkeys J Clin Endocrinol Metab 73 1991 804 810
11. JJ Hirst R Chibbar BF Mitchell Role of oxytocin in the regulation of uterine activity during pregnancy and in the initiation of labor Semin Reprod Endocrinol 11 1993 219 233
12. PW Nathanielsz MBOM Honnebier Myometrial function JO Drife AA Calder Prostaglandins and the uterus 1992 Springer-Verlag London 161 176
13. SSC Yen Neuroendocrine control of hypophyseal function 2nd ed SSC Yen RB Jaffe Reproductive endocrinology: physiology, pathophysiology and clinical management 1986 WB Saunders Philadelphia 33 74
14. RE Garfield M Ali C Yallampalli H Izumi Role of gap junctions and nitric oxide in control of myometrium contractility Semin Perinatol 19 1995 41 51
15. E Bulbring T Tomita Catecholamine action on smooth muscle Pharmacol Rev 39 1987 49 96
16. PG Marnet R Garcia-Villar MP Laurentie PL. Toutain In vivo pharmacological characterization of alpha adrenergic receptors in sheep myometrium and their physiological meaning Biol Reprod 37 1987 241 248
17. WW Hurd PA Robertson RK Riemer A Goldgien JM. Roberts Cocaine directly augments the α-adrenergic contractile response of the pregnant rabbit uterus Am J Obstet Gynecol 164 1991 182 187
18. JR Owing T Myers GA Massmann DW Sandowsky S Jenkins PW. Nathanielsz Lack of effect of maternal cocaine administration on myometrial electromyogram and maternal plasma oxytocin concentrations in pregnant sheep at 124-126 days' gestational age Obstet Gynecol 79 1992 81 84
19. HO Morishima RA Whittington Species-, gender-, and pregnancy-related differences in the pharmacokinetics and pharmacodynamics of cocaine NIDA Res Monogr 158 1995 2 21
20. TR Moore J Sorg L Miller TC Key R Resnik Hemodynamic effects of intravenous cocaine on the pregnant ewe and fetus Am J Obstet Gynecol 155 1986 883 888
21. JD Catravas IW Waters MA Wals WM Davis Acute cocaine intoxication in the conscious dog: pathophysiologic profile of acute lethality Arch Int Pharmacodyn 235 1978 328 340
22. A Sharma MA Plessinger DM Sherer CS Liang RK Miller JR Woods Jr Pregnancy enhances cardiotoxicity of cocaine: role of progesterone Toxicol Appl Pharmacol 113 1992 30 35
23. HO Morishima TB Cooper T Hara ED Miller Jr Pregnancy alters the hemodynamic responses to cocaine in the rat Dev Pharmacol Ther 19 1992 69 79
24. HO Morishima T Masaoka T Hara A Tsuji TB Cooper Pregnancy decreases the threshold for cocaine-induced convulsions in the rat J Lab Clin Med 122 1993 748 756