Expression of platelet-derived growth factor (PDGF) receptor α-subunit in mouse brain: Comparison of Patch mutants and normal littermates

Cellular and Molecular Neurobiology

Volumn 16, Issue 4, 1996, Pages 479-487

  Zhang, Frank X ^a   Hutchins, James B ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

astrocyte; brain; development; gene expression; Northern blotting; Western blotting

Indexed keywords

MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN DEVELOPMENT; BRAIN HOMOGENATE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; IMMUNOBLOTTING; MOUSE MUTANT; NERVE CELL CULTURE; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL;

ANIMALIA; MAMMALIA;

EID: 0029787244     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02150228     Document Type: Article

References (30)

1. Betsholtz, C. (1993). The PDGF genes and their regulation. Cytokines 5:11-30.
2. Bowen-Pope, D. F., Van Koppen, A., and Schatteman, G. (1991). Is PDGF really important? Testing the hypotheses. Trends Genet. 7:413-418.
3. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
4. Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
5. Claesson-Welsh, L. (1993). PDGF receptors: Structure and mechanism of action. Cytokines 5:31-43.
6. Eccleston, P. A., Funa, K., and Heldin, C.-H. (1993). Expression of platelet-derived growth factor (PDGF) and PDGF α- and β-receptors in the peripheral nervous system: An analysis of sciatic nerve and dorsal root ganglia. Dev. Biol. 155:459-470.
7. Grüneberg, H., and Truslove, G. M. (1960). Two closely linked genes in the mouse. Genet. Res. 1:69-90.
8. Hutchins, J. B. (1995). Platelet-derived growth factor receptors of mouse central nervous system cells in vitro. J. Comp. NeurOl. 360:59-80.
9. Hutchins, J. B., and Ard, M. D. (1993). Expression of platelet-derived growth factor and its receptor in rat neuronal and astroglial cultures. Mol. Cell. Neurosci. 4:250-258.
10. Hutchins, J. B., and Jefferson, V. E. (1992). Developmental distribution of platelet-derived growth factor in the mouse central nervous system. Dev. Brain Res. 67:121-135.
11. Hutchinson, J. B., and Zhang, X. (1994). Platelet-derived growth factor receptors in the developing mouse optic pathway. Vis. Neurosci. 11:33-40.
12. Levison, S. W., and McCarthy, K. D. (1991). Astroglia in culture. In Banker, G., and Goslin, K. (eds.), Culturing Nerve Cells, 2nd ed., MIT Press, Cambridge, MA, pp. 309-336.
13. Lyon, M. F., and Searle, A. G. (1989). Genetic Variants and Strains of the Laboratory Mouse. Oxford, New York.
14. Morrison-Graham, K., Schatteman, G. C., Bork, T., Bowen-Pope, D. F., and Weston, J. A. (1992). A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells. Development 115:133-142.
15. Ness, G. O., Pedersen, P.-H., Bjerkvig, R., Laerum, O. D., and Lillehaug, J. R. (1994). Three-dimensional growth of glial cells lines affects growth factor and growth factor receptor mRNA levels. Exp. Cell Res. 214:433-436.
16. Pahlman, S., Johansson, L., Westermark, B., and Nister, M. (1992). Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells. Cell Growth Diff. 3:783-790.
17. Pringle, N. P., Mudhar, H. S., Collarini, E. J., and Richardson, W. D. (1992). PDGF receptors in the rat CNS: During late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. Development 115:535-551.
18. Raines, E. W., and Ross, R. (1993). Platelet-derived growth factor in vivo. Cytokines 5:74-114.
19. Raines, E. W., Bowen-Pope, D. F., and Ross, R. (1990). Platelet-derived growth factor. In Handbook of Experimental Pharmacology, Peptide Growth Factors and Their Receptors, Vol. 95/1 (M. G. Sporn and A. B. Roberts, (Eds), Springer-Verlag, Berlin, pp. 173-262.
20. Reddy, U. R., and Pleasure, D. (1992). Expression of platelet-derived growth factor (PDGF) and PDGF receptor genes in the developing rat brain. J. Neurosci. Res. 31:670-677.
21. Ross, R., Glomset, J. A., Kariya, B., and Harker, L. (1974). A platelet-dependent serum factor that stimulates the proliferation of artieral smooth muscle cells in vitro. Proc. Natl. Acad. Sci. USA 71:1207-1210.
22. Ross, R., Raines, E. W., and Bowen-Pope, D. F. (1986). The biology of platelet-derived growth factor. Cell 46:155-169.
23. Sasahara, M., Fries, J. W., Raines, E. W., Gown, A. M., Westrum, L. E., Frosch, M. P., Ross, R., and Collins, T. (1991). PDGR B-chain in neurons of the central nervous system, Posterior pituitary, and in a transgenic model. Cell 64:217-227.
24. Schatteman, G. C., Morrison-Graham, K., Van Koppen, A., Weston, J. A., and Bowen-Pope, D. F. (1992). Regulation and role of PDGF receptor α-subunit expression during embryogenesis. Development 115:123-131.
25. 19H and patch mutations on chromosome 5. Proc. Natl. Acad. Sci. USA 88:4811-4815.
26. Smits, A., Kato, M., Westermark, B., Nistér, M., Heldin, C.-H., and Funa, K. (1991). Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF β-type receptors and respond to PDGF. Proc. Natl. Acad. Sci. USA 88:8159-8163.
27. Stephenson, D. A., Mercola, M., Anderson, E., Wang, C., Stiles, C. D., Bowen-Pope, D. F., and Chapman, V. M. (1991). Platelet-derived growth factor receptor α-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation. Proc. Natl. Acad. Sci. USA 88:6-10.
28. Towbin, H., Staehlin, T., and Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
29. Wang, C., Kelly, J., Bowen-Pope, D. F., and Stiles, C. D. (1990). Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene. Mol. Cell. Biol. 10:6781-6784.
30. Yeh, H.-J., Ruit, K. G., Wang, Y.-X., Parks, W. C., Snider, W. D., and Deuel, T. F. (1991). PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell 64:209-216.