Synthesis and α2-adrenergic activity of 2-[(methyleneamino)oxy]-N-(guanidino)ethaneimines. A bioisosteric replacement of the aryl of guanabenz-type benzylideneaminoguanidine α2-agonists with the [(methyleneamino)oxy]methyl moiety (MAOMM)

European Journal of Medicinal Chemistry

Volumn 31, Issue 9, 1996, Pages 713-716

  Balsamo, A ^b   Gentili, D ^b   Macchia, M ^b   Martinotti, E ^a   Rossello, A ^b   Scatizzi, R ^a  

^a UNIVERSITY OF PISA   (Italy)

^b NONE

Author keywords

2 (methyleneamino)oxy N (guanidino)ethaneimine; 2 adrenergic agonist; Aminoguanidine adrenergic drug; Guanabenz analog

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 2 ADRENERGIC RECEPTOR; GUANABENZ;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ELECTROSTIMULATION; GUINEA PIG; ILEUM; IN VITRO STUDY; NONHUMAN; SMOOTH MUSCLE CONTRACTILITY; STRUCTURE ACTIVITY RELATION;

EID: 0029786791     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/0223-5234(96)85880-6     Document Type: Article

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