Identification of key amino acids in a conserved cGMP-binding site of cGMP-binding phosphodiesterases: A putative NKX(n)D motif for cGMP binding

Journal of Biological Chemistry

Volumn 271, Issue 36, 1996, Pages 22240-22244

  Turko, Illarion V ^a   Haik, Tamara L ^a   McAllister Lucas, Linda M ^a   Burns, Fiona ^a,b   Francis, Sharron H ^a   Corbin, Jackie D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP PHOSPHODIESTERASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; ENZYME ACTIVITY; ENZYME BINDING; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BASE SEQUENCE; BINDING SITES; CATTLE; CONSERVED SEQUENCE; CYCLIC GMP; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; MOLECULAR SEQUENCE DATA;

BOVINAE;

EID: 0029786581     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.36.22240     Document Type: Article

References (25)

1. Beavo, J. A., Conti, M., and Heaslip, R. J. (1994) Mol. Pharmacol. 46, 399-405
2. McAllister-Lucas, L. M., Sonnenburg, W. K., Kadlecek, A., Seger, D. L., Trong, H. L., Colbran, J. L., Thomas, M. K., Walsh, K. A., Francis, S. H., Corbin, J. D., and Beavo, J. A. (1993) J. Biol. Chem. 268, 22863-22873
3. McAllister-Lucas, L. M., Haik, T. L., Colbran, J. L., Sonnenburg, W. K., Seger, D., Turko, I. V., Beavo, J. A., Francis, S. H., and Corbin, J. D. (1995) J. Biol. Chem. 270, 39671-30679
4. Weber, I. T., and Steitz, T. A. (1987) J. Mol. Biol. 198, 311-326
5. Weber, I. T., Steitz, T. A., Bubis, J., and Taylor, S. S. (1987) Biochemistry 26, 343-351
6. Weber, I. T., Shabb, J. B., and Corbin, J. D. (1989) Biochemistry 28, 6122-6127
7. Su, Y., Dostmann, W. R. G., Herberg, F. W., Durick, K., Xuong, N-h.,Ten Eyck, L., Taylor, S. S., and Varughese, K. I. (1995) Science 269, 807-813
8. Kumar, V. D., and Weber, I. T. (1992) Biochemistry 31, 4643-4649
9. Beltman, J., Becker, D. E., Butt, E., Jensen, G. S., Rybalkin, S. D., Jastorff, B., and Beavo, J. A. (1995) Mol. Pharmacol. 47, 330-339
10. Pai, E. F., Kabsch, W., Krengel, U., Holmes, K. C., John, J., and Wittinghofer, A. (1989) Nature 341, 209-214
11. Erneux, C., Couchie, D., Dumont, J. E., and Jastorff, B. (1984) Adv. Cyclic Nucleotide Protein Phosphorylation Res. 16, 107-117
12. Thomas, M. K., Francis, S. H., Beebe, S. J., Gettys, T. W., and Corbin, J. D. (1992) Adv. Second Messenger Phosphoprotein Res. 25, 45-53
13. Maniatis, T., Fritsch, E. F., and Sambrook, J. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
14. Francis, S. H., Thomas, M. K., and Corbin, J. D. (1990) in Cyclic Nucleotide Phosphodiesterases; Structure, Function, and Drug Action (Beavo, J. A., and Houslay, M. D., eds) pp. 117-140, Wiley, Chichester, UK
15. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
16. Benatti, L., Scacheri, E., Bishop, D. H. L., and Sarmientos, P. (1991) Gene (Amst.) 101, 255-260
17. Krupenko, S. A., Horstman, D. A., Wagner, C., and Cook, R. J. (1995) Protein Exp. Purif. 6, 457-464
18. Thomas, M. K., Francis, S. H., and Corbin, J. D. (1990) J. Biol. Chem. 265, 14964-14970
19. Jurnak, F. (1985) Science 230, 32-36
20. LaCour, T. F. M., Nyborg, J., Thirup, S., and Clark, B. F. C. (1985) EMBO J. 4, 2385-2388
21. Noel, J. P., Hamm, H. E., and Sigler, P. B. (1993) Nature 366, 654-663
22. Czworkoski, J., Wang, J., Steitz, T. A., and Moore, P. B. (1994) EMBO J. 13, 3661-3668
23. Wittinghofer, A. (1994) Cell 76, 201-204
24. Couchie, D., Petridis, G., Jastorff, B., and Erneux, C. (1983) Eur. J. Biochem. 136, 571-575
25. Shabb, J. B., and Corbin, J. D. (1992) J. Biol. Chem. 267, 5723-5726