Radiation damage to DNA base pairs. I. Electron paramagnetic resonance and electron nuclear double resonance study of single crystals of the complex 1-methylthymine·9-Methyladenine X-irradiated at 10 K

Radiation Research

Volumn 146, Issue 4, 1996, Pages 425-435

  Sagstuen, Einar ^a   Hole, Eli Olaug ^a   Nelson, William H ^b   Close, David M ^c  

^a UNIVERSITY OF OSLO   (Norway)

^b GEORGIA STATE UNIVERSITY   (United States)

^c EAST TENNESSEE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BASE;

ARTICLE; BASE PAIRING; CRYSTAL STRUCTURE; DNA DAMAGE; DNA DETERMINATION; ELECTRON SPIN RESONANCE; PRIORITY JOURNAL; RADIATION INJURY; X IRRADIATION;

EID: 0029785452     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579304     Document Type: Article

References (37)

1. L. Kar and W. A. Bernhard, The imidazole π-cation and barbital π-anion trapped in a cocrystalline complex X-irradiated at 12 K: An ESR-ENDOR study. J. Chem. Phys. 73, 3625-3631 (1980).
2. E. Sagstuen and D. M. Close, An ESR study of irradiated 1:1 co-crystals of 9-ethyladenine:5,5-diethylbarbituric acid (barbital) at 295 K. J. Chem. Phys. 79, 117-122 (1983).
3. D. M. Close and E. Sagstuen, ESR study of irradiated crystals of the cocrystalline complex of cytidine:salicylic acid. J. Chem. Phys. 79, 5292-5300 (1983).
4. L. Kar and W. A. Bernhard, Electron gain and electron loss radicals stabilized on the purine and pyrimidine of a cocrystal exhibiting base-base interstacking: ESR-ENDOR of X-irradiated adenosine:5-bromouracil. Radiat. Res. 93, 232-253 (1983).
5. J. Schmidt and W. Snipes, Free radical formation in a gamma-irradiated pyrimidine - purine co-crystal complex. Int. J. Radiat. Biol. 13, 101-109 (1967).
6. H. Oloff, H. Riederer and J. Hütermann, Free-radical probes of condensed-phase aspects of radiation damage mechanisms in DNA constituents: 5-halouracils. Ultramicroscopy 14, 183-193 (1984).
7. W. Flossmann, A. Müller and E. Westhof, Radicals in irradiated monocrystals of the base-pair complex 9-ethyl adenine:1-methyl uracil. Int. J. Radiat. Biol. 26, 481-492 (1974).
8. W. A. Bernhard, Solid-state radiation chemistry of DNA: The bases. In Advances in Radiation Biology, Vol. 9 (J. T. Lett and H. Adler, Eds.), pp. 199-280. Academic Press, New York, 1981.
9. D. M. Close, Radical ions and their reactions in DNA constituents: ESR/ENDOR studies of radiation damage in the solid state. Radiat. Res. 135, 1-15 (1993).
10. E. O. Hole, E. Sagstuen, W. H. Nelson and D. M. Close, Primary reduction and oxidation of thymine derivatives. ESR/ENDOR of thymidine and 1-methylthymine X-irradiated at 10 K. J. Phys. Chem. 95, 1494-1503 (1991).
11. E. O. Hole, E. Sagstuen, W. H. Nelson and D. M. Close, Free radical formation in single crystals of 9-methyladenine X-irradiated at 10 K. An electron paramagnetic resonance and electron nuclear double resonance study. Radiat. Res. 144, 258-265 (1995).
12. E. Sagstuen, E. O. Hole, W. H. Nelson and D. M. Close, Radiation induced free radicals in thymine derivatives. EPR/ENDOR of anhydrous thymine single crystals X-irradiated at 10 K. J. Phys. Chem. 96, 1121-1126 (1992).
13. K. Hoogsteen, The structure of crystals containing a hydrogen bonded complex of 1-methylthymine and 9-methyladenine. Acta Crystallogr. 12, 822-823 (1959).
14. K. Hoogsteen, The crystal and molecular structure of a hydrogenbonded complex between 1-methylthymine and 9-methyladenine. Acta Crystallogr. 16, 907-916 (1963).
15. M. N. Frey, T. F. Koetzle, M. S. Lehmann and W. C. Hamilton, Precision neutron diffraction structure determination of protein and nucleic acid components. XII. A study of hydrogen bonding in the purine-pyrimidine base pair 9-methyladenine·1-methylthymine. J. Chem. Phys. 59, 915-924 (1973).
16. 2O x-irradiated at 20 K. Int. J. Radiat. Biol. 54, 963 (1988).
17. J. Hüttermann, Electron-spin-resonance spectroscopy of radiation-induced free radicals in irradiated single crystals of thymine monohydrate. Int. J. Radial. Biol. 17, 249-259 (1970).
18. W. Flossmann, H. Zehner and A. Müller, Radicals produced in single crystals of thymine derivatives by uv and x-rays. Z. Naturforsch. 35c, 20-29 (1980).
19. J. Hüttermann, J. F. Ward and L. S. Myers, Jr., Electron spin resonance studies of free radicals in irradiated single crystals of 5-methyl cytosine. Int. J. Radiat. Phys. Chem. 3, 117-129 (1971).
20. W. Flossmann, J. Hüttermann, A. Müller and E. Westhof, Electron spin resonance of free radicals and radical pairs in irradiated single crystal of 1-methyluracil. Z. Naturforsch. 28c, 523-532 (1973).
21. J. N. Herak and C. A. McDowell, ENDOR of long-range spin inter-actions in molecular crystals. I. 1-methyluracil. J. Chem. Phys. 61, 1129-1135 (1974).
22. E. Westhof, W. Flossmann, H. Zehner and A. Müller, Formation of H-addition radicals in some pyrimidine and purine derivatives. J. Chem. Soc. Faraday Disc. 63, 248-254 (1977).
23. H. Oloff and E. Sagstuen, Radiation-induced free radicals in solid 5-halouracil derivatives: single crystals of 1-methyl-5-bromouracil. Int. J. Radiat. Biol. 40, 493-505 (1981).
24. A. Dulčićand J. N. Herak, Crystal structure dependence of radiation-induced radicals in thymine: An EPR study. Radiat. Res. 47, 573-580 (1971).
25. D. M. Close and W. H. Nelson, ESR and ENDOR study of adenosine single crystals X-irradiated at 10 K. Radiat. Res. 117, 367-378 (1989).
26. D. M. Close, W. H. Nelson, E. Sagstuen and E. O. Hole, ESR and ENDOR study of single crystals of deoxyadenosine monohydrate X-irradiated at 10 K. Radiat. Res. 137, 300-309 (1994).
27. H. Zehner, E. Westhof, W. Flossmann and A. Müller, Formation of H-adduct radicals in adenine derivatives: Part II. Z. Naturforsch. 32c, 1-10 (1976).
28. H. Zehner, W. Flossmann and E. Westhof, Formation of H-adduct radicals in adenine derivatives. Z. Naturforsch. 31c, 225-231 (1975).
29. L. P. Candeias and S. Steenken, Electron adducts of adenine nucleosides and nucleotides in aqueous solution: Protonation at two carbon sites (C2 and C8) and intra- and intermolecular catalysis by phosphate. J. Phys. Chem. 75, 626-631 (1992).
30. W. H. Nelson, E. Sagstuen, E. O. Hole and D. M. Close, On the nature of the primary oxidation product in DNA. Radiat. Res. 131, 10-17 (1992).
31. S. Steenken, Electron-transfer-induced acidity/basicity and reactivity changes of purine and pyrimidine bases. Consequences of redox processes for DNA base pairs. Free Radical Res. Commun. 16, 349-379 (1992).
32. S. C. Lillicrap and E. M. Fielden, Luminescence kinetics following pulse irradiation-IV. A purine pyrimidine crystal complex. Int. J. Radiat. Phys. Chem. 1, 479-493 (1969).
33. •- with thymine derivatives: A pulse radiolysis study with optical and conductance detection. J. Phys. Chem. 94, 8186-8192 (1990).
34. M. J. S. Dewar and J. J. P. Stewart, AMPAC - Austin method 1 package, QCPE Program No. 506.
35. M. D. Sevilla, An electron spin resonance study of the photoionization of thymine. The thymine cation and anion radicals. J. Phys. Chem. 75, 626-631 (1971).
36. M. D. Sevilla, C. VanPaemel and G. Zorman, Reactions of the cation and the anion radicals of several DNA bases. J. Phys. Chem. 76, 3577-3582 (1972).
37. W. A. Bernhard, J. Barnes, K. R. Mercer and N. Mroczka, The influence of packing on free radical yields in crystalline nucleic acids: The pyrimidine bases. Radiat. Res. 140, 199-214 (1994).