Ability of FGFs to promote the outgrowth and proliferation of limb mesoderm is dependent on IGF-I activity

Developmental Dynamics

Volumn 206, Issue 4, 1996, Pages 463-469

  Dealy, Caroline N ^a   Clarke, Kevin ^a   Scranton, Victoria ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Embryo; FGF; IGF I; Limb; Msx 1

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 4; MESSENGER RNA; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; SOMATOMEDIN C;

ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHICK EMBRYO; CONTROLLED STUDY; DIFFERENTIATION; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EXPLANT; GENE EXPRESSION; HOMEOBOX; LIMB BUD; LIMB DEVELOPMENT; MESODERM; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE GROWTH;

ANIMALS; CELL DIVISION; CELL MOVEMENT; CHICK EMBRYO; EXTREMITIES; FIBROBLAST GROWTH FACTORS; INSULIN-LIKE GROWTH FACTOR I; MESODERM;

ANIMALIA;

EID: 0029785140     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199608)206:4<463::AID-AJA12>3.0.CO;2-Y     Document Type: Article

References (38)

1. Anderson, R., Landry, M., and Muneoka, K. (1993) Maintenance of ZPA signalling in cultured mouse limb bud cells. Development 117: 1421-1433.
2. Coelho, C.N.D., Krabbenhoft, K., Upholt, W.B., Fallon, J.F., and Kosher, R.A. (1991) Altered expression of the chicken homeobox-containing genes GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos. Development 113:1487-1493.
3. Coelho, C.N.D., Upholt, W.B., and Kosher, R.A. (1992) The expression pattern of the chicken homeobox-containing gene GHox-7 in developing polydactylous limb buds suggests its involvement in apical ectodermal ridge-directed outgrowth of limb mesoderm and in programmed cell death. Differentiation 52:129-137.
4. Crossley, P.H., and Martin, G.R. (1995) The mouse fgf-8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121:439-451.
5. Dealy, C.N., and Kosher, R.A. (1995) Studies on insulin-like growth factor-I and insulin in chick limb morphogenesis. Dev. Dyn. 202: 67-79.
6. Dealy, C.N., and Kosher, R.A. (1996) IGF-I, insulin and FGFs induce outgrowth of the limb buds of amelic mutant chick embryos. Development 122:1323-1330.
7. Fallon, J.F., Lopez, A., Ros, M. A., Savage, M. P., Olwin, B. B., and Simandl, B. K. (1994) FGF-2: Apical ectodermal ridge growth signal for chick limb development. Science 264:104-107.
8. Geduspan, J.S., and Solursh, M. (1993) Effects of the mesonephros and insulin-like growth factor I on chondrogenesis of limb explants. Dev. Biol. 156:500-508.
9. Geduspan, J.S., Padanilam, B.J., and Solursh, M. (1992) Coordinate expression of IGF-I and its receptor during limb outgrowth. Dev. Dyn. 195:67-73.
10. Green, B.N., Jones, S.B., Streck, R. D., Wood, T.L., Rotwein, P. and Pintar, J.E. (1994) Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development. Endocrinology 134:954-962.
11. Hamburger, V., and Hamilton, H.L. (1951) A series of normal stages in the development of the chick embryo. J. Morphol. 83:49-92.
12. Hayashi, Y., Koike, M., Matsutani, M., and Hoshino, T. (1988) Effects of fixation time and enzymatic digestion on immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue. J. Histochem. Cytochem. 36:511-514.
13. Kosher, R. A., Savage, M. P., and Chan, S.-C. (1979) In vitro studies on the morphogenesis and differentiation of the mesoderm subjacent to the apical ectodermal ridge of the embryonic chick limb-bud. J. Embryol. Exp. Morphol. 50:75-97.
14. Laufer, E., Nelson, C.E., Johnson, R. L., Morgan, B. A., and Tabin, C. (1994) Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79:993-1003.
15. Mahmood, R., Bresnick, J., Hornbruch, A., Mahony, C., Morton, N., Colquhoun, K., Martin, P., Lumsden, A., Dickson, C., and Mason, I. (1995) A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth. Curr. Biol. 5:797-806.
16. Mallein-Gerin, F., Kosher, R.A., Upholt, W.B., and Tanzer, M.L. (1988) Temporal and spatial analysis of cartilage proteoglycan core protein gene expression during limb development by in situ hybridization. Dev. Biol. 126:337-345.
17. Niswander, L., and Martin, G.R. (1992) Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114:755-768.
18. Niswander, L., and Martin, G. R. (1993a) FGF-4 and BMP-2 have opposite effects on limb growth. Nature 361:68-71.
19. Niswander, L., and Martin, G.R. (1993b) FGF-4 regulates expression of Evx-1 in the developing mouse limb. Development 119:287-294.
20. Niswander, L., Tickle, C., Vogel, A., Booth, I., and Martin, G. R. (1993) FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75:579-587.
21. Niswander, L., Jeffrey, S., Martin, G.R., and Tickle, C. (1994) A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371:609-612.
22. Ohuchi, H., Yoshioka, H., Tanaka, H., Kawakami, Y., Nohno, T., and Noji, S. (1994) Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis. Biochem. Biophys. Res. Commun. 204:882-888.
23. Ralphs, J.R., Wylie, L., and Hill, D. J. (1990) Distribution of insulin-like growth factor peptides in the developing chick embryo. Development 109:51-58.
24. Riddle, R.D., Johnson, R.L., Laufer, E., and Tabin, C. (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75:1401-1416.
25. Riley, B.B., Savage, M.P., Simandl, B. K., Olwin, B. B., and Fallon, J. F. (1993) Retroviral expression of FGF-2 (bFGF) affects patterning in chick limb bud. Development 118:95-104.
26. Robert, B., Lyons, G., Simabdl, K., Kuroiwa, A., and Buckingham, M. (1991) The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes Dev. 5:2363-2374.
27. Ros, M.A., Lyons, G., Kosher, R.A., Upholt, W.B. Coelho, C.N.D., and Fallon, J.F. (1992) Apical ridge dependent and independent mesodermal domains of Ghox-7 and Ghox-8 expression in chick limb. Development 116:811-818.
28. Ros, M.A., Lyons, G.E., Mackem, S., and Fallon, J.F. (1994) Recombinant limbs as a model to study homeobox gene regulation during limb development. Dev. Biol. 166:59-72.
29. Sainte-Marie, G. (1962) A paraffin embedding technique for studies employing immunofluorescence. J. Histochem. Cytochem. 10:250-256.
30. Saunders, J.W. Jr. (1977) The experimental analysis of chick limb development. In: "Vertebrate Limb and Somite Morphogenesis," Ede, D.A., Hinchliffe, J.R., and Balls, M. (eds). Cambridge: Cambridge University Press, pp. 1-24.
31. Saunders, J.W. Jr., and Gasseling, M.T. (1968) Ectodermal-mesenchymal interactions in the origin of limb symmetry. In: "Epithelial-Mesenchymal Interactions," Fleischmajer, R. and Billingham, R.F. (eds). Baltimore: Williams and Wilkins, pp. 78-97.
32. Savage, M. P., Hart, C. E., Riley, B. B., Sasse, J., Olwin, B. B., and Fallon, J. F. (1993) Distribution of FGF-2 suggests it has a role in chick limb bud growth. Dev. Dyn. 198:159-170.
33. Song, K., Wang, Y., and Sassoon, D. (1992) Expression of Hox-7.1 in myoblasts inhibits terminal differentiation and induces cell transformation. Nature 360:477-481.
34. Streck, R. D., Wood, T. L., Hsu, M.-S., and Pintar, J. E. (1992) Insulin-like growth factor-I and -II and insulin-like growth factor binding protein-2 RNA are expressed in adjacent tissues within rat embryonic and fetal limbs. Dev. Biol. 151:586-596.
35. Suzuki, H. R., Sakamoto, H., Yoshida, T., Sugimura, T., Terada, M., and Solursh M. (1992) Localization of Hst1 transcripts to the apical ectodermal ridge of the mouse embryo. Dev. Biol. 150:219-222.
36. Taylor, G.P., Anderson, R., Reginelli, A.D., and Muneoka, K. (1994) FGF-2 induces regeneration of the chick limb bud. Dev. Biol. 163: 282-206.
37. Vogel, A., and Tickle, C. (1993) FGF-4 maintains polarizing activity of posterior limb cells in vivo and vitro. Development 119:199-206.
38. Zwilling, E. (1961) Limb morphogenesis. Adv. Morphogen. 1:301-330.