Antioxidant-sensitive regulation of inflammatory-response genes in Kaposi's sarcoma cells

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Volumn 13, Issue 1, 1996, Pages 1-11

  Offermann, Margaret K ^a,c   Lin, Jung Chung ^b   Mar, Eng Chun ^b   Shaw, Renee ^a   Yang, Jing ^a   Medford, Russell M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Cellular adhesion molecule; Cytokine; Inflammation; Kaposi's sarcoma; Oxidation

Indexed keywords

ANTIOXIDANT; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; POLYCYTIDYLIC ACID; POLYINOSINIC ACID; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMATE; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPATHOGENESIS; KAPOSI SARCOMA; LYMPHOCYTIC INFILTRATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; REGULATOR GENE; VIRUS EXPRESSION;

HERPES; HUMAN HERPESVIRUS 8;

EID: 0029785038     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199609000-00001     Document Type: Article

References (61)

1. Delli Bovi PD, Donti E, Knowles DMI, et al. Presence of chromosomal abnormalities and lack of AIDS retrovirus DNA sequences in AIDS-associated Kaposi's sarcoma. Cancer Res 1986;46:6333-8.
2. Kaplan MH, Susin M, Pahwa SG, et al. Neoplastic complications of HTLV-III infection. Am J Med 1987;82:389-96.
3. Chang Y, Cesarman E, Pessin M, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994;266:1865-9.
4. Moore PS, Chang Y. Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection. N Engl J Med 1995;332:1181-5.
5. Dupin N, Grandadam M, Calvez V, et al. Herpesvirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma. Lancet 1995;345:761-2.
6. Huang YQ, Li JJ, Kaplan MH, et al. Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma. Lancet 1995;345:759-61.
7. Boshoff C, Shulz T, Kennedy M, et al. Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells. Nature Med 1995;1:1274-8.
8. Rady P, Yen A, Rollefson J, et al. Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients. Lancet 1995;345:1339-40.
9. Oxholm A. Epidermal expression of interleukin-6 and tumour necrosis factor-alpha in normal and immunoinflammatory skin states in humans. Apmis Suppl 1992;24:1-32.
10. Oxholm A, Oxholm P, Permin H, Bendtzen K. Epidermal tumour necrosis factor alpha and interleukin 6-like activities in AIDS-related Kaposi's sarcoma: an immunohistological study. Apmis 1989;97:533-8.
11. Schulze-Osthoff K, Goerdt S, Sorg C. Expression of basic fibroblast growth factor (bFGF) in Kaposi's sarcoma: an immunohistologic study. J Invest Dermatol 1990;95:238-40.
12. Cai J, Gill PS, Masood R, et al. Oncostatin-M is an autocrine growth factor in Kaposi's sarcoma. Am J Pathol 1994;145: 74-9.
13. Huang Y, Friedman-Kien A, Li J, Nickoloff B. Cultured Kaposi's sarcoma cell lines express factor XIIIa, CD14, and VCAM-1, but not factor VIII or ELAM-1. Arch Dermatol 1993;129:1291-6.
14. Ensoli B, Nakamura S, Salahuddin SZ, et al. AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects. Science 1989;243:223-6.
15. Miles SA, Rezai AR, Salazar GJF, et al. AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6. Proc Natl Acad Sci USA 1990;87:4068-72.
16. Miles SA, Martinez MO, Rezai A, et al. Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells. Science 1992;255:1432-4.
17. Nair BC, DeVico AL, Nakamura S, et al. Identification of a major growth factor for AIDS-Kaposi's sarcoma cells as Oncostatin M. Science 1992;255:1430-4.
18. YangJ, Xu Y, Zhu C, Hagan MK, LawleyT, Offermann MK. Regulation of adhesion molecule expression in Kaposi's sarcoma cells. J Immunol 1994;152:361-73.
19. Yang J, Hagan MK, Offermann M. Induction of IL-6 gene expression in Kaposi's sarcoma cells. J Immunol 1994;152: 943-55.
20. Cohen J. Controversy: Is KS really caused by new herpesvirus? Science 1995;268:1847-8.
21. Schreck R, Meier B, Mannel DN, Droge W, Baeurle PA. Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J Exp Med 1992;175:1181-94.
22. Marui N, Offermann M, Swerkick R, et al. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant sensitive mechanism in human vascular endothelial cells. J Clin Invest 1993;92:1866-73.
23. Collins T. Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion. Lab Invest 1993;68:499-508.
24. Iademarco MF, McQuillan JJ, Rosen GD, Dean DC. Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1). J Biol Chem 1992;267:16323-9.
25. Neish AS, Williams AJ, Palmer HJ, Whitley MZ, Collins T. Functional analysis of the human vascular cell adhesion molecule 1 promoter. J Exp Med 1992;176:1583-93.
26. Whelan J, Ghersa P, van Hooft HR, et al. An NF-κB-like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule 1 (ELAM-1) gene transcription. Nucleic Acids Res 1991;19:2645-53.
27. Caughman SW, Li LJ, Degitz K. Characterization and functional analysis of interferon-gamma-induced intercellular adhesion molecule-1 expression in human keratinocytes and A-431 cells. J Invest Dermatol 1990;98(6S):61S-5S.
28. Sehgal PB. Regulation of IL6 gene expression. Res Immunol 1992;143:724-33.
29. Selden RF. Analysis of RNA by northern hybridization. In: Ausubel FM, Brent R, Kingston RE, et al. eds. Current protocols in molecular biology. New York: John Wiley and Sons, 1987:4.9.1-.8.
30. Lin JC, Lin SC, De BK, et al. Precision of genotyping of Epstein-Barr virus by polymerase chain reaction using three gene loci (EBNA-2, EBNA-3C, and EBER): predominance of type A virus associated with Hodgkin's disease. Blood 1993;81:3372-81.
31. Feinberg AP, Vogelstein B. A technique for radiolabelling DNA restriction endonuclease fragments of high specific activity. Anal Biochem 1983;132:6-13.
32. Tomassini JE, Graham D, DeWitt CM, Lineberger DW, Rodkey JA, Colonno RJ. cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1. Proc Natl Acad Sci USA 1989;86: 4907-11.
33. Osborn L, Hession C, Tizard R, et al. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 1989;59:1203-11.
34. Bevilacqua MP, Stengelin S, Gimbrone MAJ, Seed B. Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 1989;243:1160-5.
35. Sutherland GR, Baker E, Callen DF, et al. Interleukin 4 is at 5q31 and interleukin 6 is at 7p15. Hum Genet 1988;79:335-7.
36. Makgoba MW, Sanders ME, Luce G, et al. ICAM-1: a ligand for LFA-1-dependent adhesion of B, T, and myeloid cells. Nature 1988;331:86.
37. Dignam J, Lebovitz R, Roeder R. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983;11: 1476-89.
38. 2+ dependence, and differential half-site recognition. J Biol Chem 1991;266:252-60.
39. Chodosh L. DNA-protein interactions. In: Ausubel FM, Brent R, Kingston RE, eds. Current protocols in molecular biology. New York: John Wiley and Sons, 1987:12.2.1-10.
40. Schreck R, Meier B, Mannel DN, Droge W, Baeuerle PA. Dithiocarbamates as potent inhibitors of nuclear factor-κB activation in intact cells. J Exp Med 1992;175:1181-94.
41. Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1 EMBO J 1991;10:2247-58.
42. Schreck R, Baeuerle P. A role for oxygen radicals as second messengers. Trends Cell Biol 1991;1:39-42.
43. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J 1993;12:2005-15.
44. Kunsch C, Ruben SM, Rosen CA. Selection of optimal κB/ Rel DNA binding motifs: interaction of both subunits of NF-κB with DNA is required for transcriptional activation. Mol Cell Biol 1992;12:4412-21.
45. Fan C-M, Maniatis T. A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence. Genes Dev 1990;4:29-42.
46. Degitz K, Li LJ, Caughman SW. Cloning and characterization of the 5′-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene. J Biol Chem 1991; 266:14024-30.
47. Libermann TA, Baltimore D. Activation of interleukin-6 gene expression through the NF-κB transcription factor. Mol Cell Biol 1990;10:2327-34.
48. Baker DH, Wood RJ. Cellular antioxidant status and human immunodeficiency virus replication. Nutr Rev 1992;50:15-18.
49. Baruchel S, Wainberg MA. The role of oxidative stress in disease progression in individuals infected by the human immunodeficiency virus. J Leuk Biol 1992;52:111-4.
50. Lane H, Masur H, Gellman E, et al. Correlation between immunologic function and clinical subpopulations of patients with the acquired immune deficiency syndrome. Am J Med 1985;78:417.
51. de Wit R, Raasveld MHM, ten Berge RJM, van der Wouw PA, Bakker PJM, Veenhof CHN. Interleukin-6 concentrations in the serum of patients with AIDS-associated Kaposi's sarcoma during treatment with interferon-alpha. J Intern Med 1991;229:539-42.
52. Spornraft P, Froschl M, Ring J, et al. T4/T8 ratio and absolute T4 cell numbers in different clinical stages of Kaposi's sarcoma in AIDS. Br J Dermatol 1988;119:1-9.
53. Friedman-Birnbaum R, Weltfriend S, Pollack S. Classic Kaposi's sarcoma: T-lymphocyte subsets, T4/T8 ratio, and NK cell activity. J Am Acad Dermatol 1991;937-40.
54. Aboulafavia D, Miles S, Saks S, Mitsuyasu R. Intravenous recombinant tumor necrosis factor in the treatment of AIDS-related Kaposi's sarcoma. J Acquir Immune Defic Syndr 1989;2:54-8.
55. Vogel J, Hinrichs S, Reynolds R, Luciw P, Jay G. The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice. Nature 1988;335:606-11.
56. Suster S. Alterations in tumor angiogenesis associated with stable expression of the HIV tat gene. Mol Carcinogen 1992; 5:293-300.
57. Ensoli B, Barillari G, Salahuddin SZ, Gallo RC, Wong-Staal F. Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 1990;345:84-6.
58. Corbeil J, Evans LA, Vasak E, Cooper DA, Penny R. Culture and properties of cells derived from Kaposi sarcoma. J Immunol 1991;146:2972-6.
59. Salahuddin SZ, Nakamura S, Bibelfeld P, et al. Angiogenic properties of Kaposi's sarcoma-derived cells after long-term culture in vitro. Science 1988;242:430-3.
60. Staal FJ, Roederer M, Raju PA, et al. Antioxidants inhibit stimulation of HIV transcription. Aids Res Hum Retrovir 1993;9:299-306.
61. Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 1995;332:1186-91.