Induction of apoptosis by tamoxifen-activation of a p53-estrogen receptor fusion protein expressed in E1A and T24 H-ras transformed p53(-/-) mouse embryo fibroblasts

Oncogene

Volumn 13, Issue 4, 1996, Pages 739-748

  Vater, Carol A ^a   Bartle, Laura M ^a   Dionne, Cheryl A ^a   Littlewood, Trevor D ^b   Goldmacher, Victor S ^a  

^a Apoptosis Technology Inc   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Apoptosis; p53; Tamoxifen

Indexed keywords

4 HYDROXYTAMOXIFEN; ESTROGEN RECEPTOR; HYBRID PROTEIN; NOCODAZOLE; PROTEIN P53; TAMOXIFEN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG SENSITIVITY; EMBRYO; FIBROBLAST; GENE FUSION; MOUSE; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL;

ADENOVIRUS E1A PROTEINS; ANIMALS; APOPTOSIS; CELL LINE, TRANSFORMED; EMBRYO; ESTROGEN ANTAGONISTS; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, RAS; MICE; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; TAMOXIFEN; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MURINAE;

EID: 0029784962     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Alderson LM, Castleberg RL, Harsh IVGR, Louis DN and Henson JW. (1995). Cancer Res., 55, 999-1001.
2. Baker SJ, Markowitz S, Fearon ER, Willson JKV and Vogelstein B. (1990). Science, 249, 912-915.
3. Barak Y, Juven T, Haffner R and Oren M. (1993). EMBO J., 12, 461-468.
4. Bond JA, Wyllie FS and Wynford-Thomas D. (1994). Oncogene, 9, 1885-1889.
5. Casey G, Lo-Hsueh M, Lopez ME, Vogelstein B and Stanbridge EJ. (1991). Oncogene, 6, 1791-1797.
6. Chen P-L, Chen Y, Bookstein R and Lee W-H. (1990). Science, 250, 1576-1580.
7. Chilosi M, Doglioni C, Menestrina F, Montagna L, Rigo A, Lestani M, Barbareschi M, Scarpa A, Mariuzzi GM and Pizzolo G. (1994). Blood, 84, 4295-4300.
8. Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML and Wyllie AH. (1993). Nature, 362, 849-852.
9. Cripps KJ, Purdie CA, Carder PJ, White S, Komine K, Bird CC and Wyllie AH. (1994). Oncogene, 9, 2739-2743.
10. Cross SM, Sanchez CA, Morgan CA, Schimke MK, Ramel S, Idzerda RL, Raskind WH and Reid BJ. (1995). Science. 267, 1353-1356.
11. Danielian PS, White R, Hoare SA, Fawell SE and Parker MG. (1993). Mol. Endocrinol., 7, 232-240.
12. Diller L, Kassel J, Nelson CE, Gryka MA, Litwak G, Gebhardt M, Bressac B, Ozturk M, Baker SJ, Vogelstein B and Friend SH. (1990). Mol. Cell. Biol., 10, 5772-5781.
13. Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C and Levine AJ. (1993). Nature Genet., 4, 42-46.
14. Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery Jr CA, Butel JS and Bradley A. (1992). Nature, 356, 215-221.
15. Donehower LA, Godley LA, Aldaz CM, Pyle R, Shi Y-P, Pinkel D, Gray J, Bradley A, Medina D and Varmus HE. (1995). Genes & Dev., 9, 882-895.
16. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B. (1993). Cell, 75, 817-825.
17. El Rouby S, Thomas A, Costin D, Rosenberg CR, Potmesil M, Silber R and Newcomb EW. (1994). Blood, 82, 3452-3459.
18. Esrig D, Elmajian D, Groshen S, Freeman JA, Stein JP, Chen S-C, Nichols PW, Skinner DG, Jones PA and Cote RJ. (1994). N. Engl. J. Med., 331, 1259-1264.
19. Furth EF, Thilly WG, Penman BW, Liber HL and Rand WM. (1981). Anal. Biochem., 110, 1-8.
20. Greenblatt MS, Bennett WP, Hollstein M and Harris CC. (1994). Cancer Res., 54, 4855-4878.
21. Harris C and Hollstein M. (1993). N. Engl. J. Med., 329, 1318-1327.
22. Harvey M, Sands AT, Weiss RS, Hegi ME, Wiseman RW, Pantazis P, Giovanella BC, Tainsky MA, Bradley A and Donehower LA. (1993). Oncogene, 8, 2457-2467.
23. Herrmann M, Lorenz H-M, Voll R, Grunke M, Woith W and Kalden JR. (1994). Nucl. Acids Res., 22, 5506-5507.
24. Hsiao M, Low J, Dorn E, Ku D, Pattengale P. Yeargin J and Haas M. (1994). Amer. J. Path., 145, 702-714.
25. Johnson DA, Gautsch JW, Sportsman JR and Elder JH. (1984). Gene Anal. Tech., 1, 3-8.
26. Johnson P, Gray D, Mowat M and Benchimol S. (1991). Mol. Cell. Biol., 11, 1-11.
27. Kemp CJ, Wheldon T and Balmain A. (1994). Nature Genetics, 8, 66-69.
28. Laemmli UK. (1970). Nature, 227, 680-685.
29. Landers JE, Haines DS, Strauss III JF and George DL. (1994). Oncogene, 9, 2745-2750.
30. Lin HJ, Eviner V, Prendergast GC and White E. (1995). Mol. Cell. Biol., 15, 4536-4544.
31. Littlewood TD, Hancock DC, Danielian PS, Parker MG and Evan GI. (1995). Nucl. Acids Res., 23, 1686-1690.
32. Lowe SW, Ruley HE, Jacks T and Housman DE. (1993a). Cell, 74, 957-967.
33. Lowe SW, Schmitt EM, Smith SW, Osborne BA and Jacks T. (1993b). Nature, 362, 847-849.
34. Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE and Jacks T. (1994a). Science. 266, 807-810.
35. Lowe SW, Jacks T, Housman DE and Ruley HE. (1994b). Proc. Natl. Acad. Sci. USA, 91, 2026-2030.
36. Mercer WE, Shields MT, Amin M, Sauve GJ, Appella E, Romano JW and Ullrich SJ. (1990). Proc. Natl. Acad. Sci. USA, 87, 6166-6170.
37. Morgenstern JP and Land H. (1990). Nucl. Acids Res., 18, 3587-3596.
38. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali R, Harris CC and Vogelstein B. (1989). Nature, 342, 705-708.
39. Otto A and Deppert W. (1993). Oncogene, 8, 2591-2603.
40. Picard D, Salser SJ and Yamamoto KR. (1988). Cell, 54, 1073-1080.
41. Renzing J and Lane DP. (1995). Oncogene, 10, 1865-1868.
42. Rocmer K and Friedmann T. (1993). Proc. Natl. Acad. Sci. USA, 90, 9252-9256.
43. Runnenbaum IB, Yee J-K, Keiback DG, Sukumar S and Friedmann T. (1994). Anticancer Res., 14, 1137-1144.
44. Sambrook J, Fritsch EF and Maniatis T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory: Cold Spring Harbor, New York.
45. Shaw P, Bovey R, Tardy S, Sahli R, Sordat B and Costa J. (1992). Proc. Natl. Acad. Sci. USA, 89, 4495-4499.
46. Srivastava S, Wang S, Tong YA, Hao Z-M and Chang EH. (1993). Cancer Res., 53, 4452-4455.
47. Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T and van Dyke T. (1994). Cell, 78, 703-711.
48. Thompson TC, Park SH, Timme TL, Ren C, Eastham JA, Donehower LA, Bradley A, Kadmon D and Yang G. (1995). Oncogene, 10, 869-879.
49. Tsukada T, Tomooka Y, Takai S, Ueda Y, Nishikawa S, Yagi T, Tokunaga T, Takeda N, Suda Y, Abe S, Matsuo I, Ikawa Y and Aizawa S. (1993). Oncogene, 8, 3313-3322.
50. van Meir EG, Roemer K, Diserens A-C, Kikuchi T, Rempel SA, Haas M, Su Huang H-J, Friedmann T, de Tribolet M and Cavenee WK. (1995). Proc. Nutl. Acad. Sci. USA, 92, 1008-1012.
51. Wang Y, Ramqvist T, Szekely L, Axelson H, Klein G and Wiman KG. (1993). Cell Growth & Differ., 4, 467-473.
52. Wattel E, Preudhomme C, Hecquet B, Vanrumbeke M, Quesnel B, Dervite I, Morel P and Fenaux P. (1994). Blood, 84, 3148-3157.
53. Williams BO, Remington L, Albert DM, Mukai S, Bronson RT and Jacks T. (1994). Nature Genetics, 7, 480-484.
54. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A and Oren M. (1991). Nature, 352, 345-347.
55. Zigler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Remington L, Jacks T and Brash DE. (1994). Nature, 372, 773-776.