Effects of genetic obesity on rat upper airway muscle and diaphragm contractile properties

European Respiratory Journal

Volumn 9, Issue 10, 1996, Pages 2139-2144

  Van Lunteren, E ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

contraction; diaphragm muscle; pharyngeal muscle; sleep apnoea; sternohyoid muscle; upper airway

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAPHRAGM; HEREDITY; IN VITRO STUDY; MUSCLE TONE; NONHUMAN; OBESITY; PHARYNX; PRIORITY JOURNAL; SLEEP APNEA SYNDROME; SMOOTH MUSCLE CONTRACTION;

AGING; ANIMALS; DIAPHRAGM; ELECTRIC STIMULATION; ISOMETRIC CONTRACTION; MALE; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE RELAXATION; NECK MUSCLES; OBESITY; PHARYNGEAL MUSCLES; RATS; RATS, ZUCKER; SLEEP APNEA SYNDROMES; STRESS, MECHANICAL;

EID: 0029784903     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Deegan PC, McNicholas WT. Pathophysiology of obstructive sleep apnoea. Eur Respir J 1995; 8: 1161-1178.
2. McNamara SG, Grunstein R, Sullivan CE. Obstructive sleep apnoea. Thorax 1993; 48: 754-764.
3. Walsh RE, Michaelson ED, Harkleroad LE, Zighelboim A, Sackner MA. Upper airway obstruction in obese patients with sleep disturbance and somnolence. Ann Intern Med 1972; 76: 185-192.
4. Vgontzas AN, Tan TL, Bixler EO, Martin LF, Shubert D, Kales A. Sleep apnea and sleep disruption in obese patients. Arch Intern Med 1994; 154: 1705-1711.
5. Parkas GA, Schlenker EH. Pulmonary ventilation and mechanics in morbidly obese Zucker rats. Am J Respir Crit Care Med 1994; 150: 356-362.
6. Farkas GA, Gosselin LE, Zhan W, Schlenker EH, Sieck GC. Histochemical and mechanical properties of diaphragm muscle in morbidly obese Zucker rats. J Appl Physiol 1994; 77: 2250-2259.
7. Petrof BJ, Pack AI, Kelly AM, Eby J, Hendricks JC. Pharyngeal myopathy of loaded upper airway in dogs with sleep apnea. J Appl Physiol 1994; 76: 1746-1752.
8. Series F, Cote C, Simoneau J-A, et al. Physiologic, metabolic, and muscle fiber type characteristics of musculus uvulae in sleep apnea/hypopnea syndrome and in snorers. J Clin Invest 1995; 95: 20-25.
9. Smirne S, Iannaccone S, Ferini-Strambi L, Comola M, Colombo E, Nemni R. Muscle fibre type and habitual snoring. Lancet 1991; 337: 597-599.
10. Yarom R, Sagher U, Havivi Y, Peled IJ, Wexler MR. Myofibers in tongues of Down's syndrome. J Neurol Sci 1986; 73: 279-287.
11. Petrof BJ, Kelly AM, Rubinstein NA, Pack AI. Effect of hypothyroidism on myosin heavy chain expression in rat pharyngeal dilator muscles. J Appl Physiol 1992; 73: 179-187.
12. Brozanski BS, MJ Daood, JF Watchko, WA LaFramboise, Guthrie RD. Postnatal expression of myosin isoforms in the genioglossus and diaphragm muscles. Pediatr Pulmonol 1993; 15: 212-219.
13. van Lunteren E, Martin RJ. Pharyngeal dilator muscle contractile and endurance properties in neonatal piglets. Respir Physiol 1993; 92: 65-75.
14. van Lunteren E, Vafaie H, Salomone RJ. Comparative effects of aging on pharyngeal and diaphragm muscles. Respir Physiol 1995; 99: 113-125.
15. Finnimore AJ, Jackson RV, Morton A, Lynch E. Sleep hypoxia in myotonic dystrophy and its correlation with awake respiratory function. Thorax 1994; 49: 66-70.
16. Khan Y, Heckmatt JZ. Obstructive apnoeas in Duchenne muscular dystrophy. Thorax 1994; 49: 157-161.
17. Bray GA. The Zucker fatty rat: a review. Fed Proc 1977; 36: 148-153.
18. Zucker LM, Zucker TF. Fatty, a new mutation in the rat. J Hered 1961; 52: 275-278.
19. van Lunteren E, Manubay P. Contractile properties of feline genioglossus, sternohyoid and sternothyroid muscles. J Appl Physiol 1992; 72: 1010-1015.
20. van Lunteren E, Vafaie H. Force potentiation in respiratory muscles: comparison of diaphragm and sternohyoid. Am J Physiol 1993; 264: R1095-R1100.
21. Roberts JL, Reed WR, Thach BT. Pharyngeal airway-stabilizing function of sternohyoid and sternothyroid muscles in the rabbit. J Appl Physiol: Respirat Environ Exercise Physiol 1984; 57: 1790-1795.
22. Strohl KP, Wolin AD, van Lunteren E, Fouke JM. Assessment of muscle action on upper airway stability in anesthetized dogs. J Lab Clin Med 1987; 110: 221-230.
23. Dick TE, van Lunteren E. Fiber subtype distribution of pharyngeal dilator muscles and diaphragm in cat. J Appl Physiol 1990; 68: 2237-2240.
24. Series F, Cote C, St Pierre S, Marc I. Influence of upper airway (UA) collapsibility on the contractile profile of musculus uvulae (MU) (Abstract). Am J Respir Crit Care Med 1995; 151: A558.
25. van Lunteren E, Salomone RJ, Manubay P, Supinski GS, Dick TE. Contractile and endurance properties of geniohyoid and diaphragm muscles. J Appl Physiol 1990; 69: 1992-1997.
26. Kuei JH, Shadmehr R, Sieck GC. Relative contribution of neurotransmission failure to diaphragm fatigue. J Appl Physiol 1990; 68: 174-180.
27. Pujol A, LeFaucheur L, Ecolan P, Picon L, Penicaud L. Fiber type composition and enzyme activities of muscles in two models of obese rats. Comp Biochem Physiol 1993; 106B: 269-272.
28. Torgan CE, Broxinick JT, Kastello GM, Ivy JL. Muscle morphological and biochemical adaptations to training in obese Zucker rats. J Appl Physiol 1989; 67: 1807-1813.
29. Wardlaw GM, Kaplan HL, Lanza-Jacoby S. Effect of treadmill training on muscle oxidative capacity and accretion in young male obese and nonobese Zucker rats. J Nutr 1986; 116: 1841-1852.
30. Shelton KE, Woodson H, Gay S, Suratt PM. Pharyngeal fat in obstructive sleep apnea. Am Rev Respir Dis 1993; 148: 462-466.