The EORTC trials for acute myelogenous leukemia;Les essais cliniques de l'EORTC pour la leucemie aigue myeloide

Hematology and Cell Therapy

Volumn 38, Issue 3, 1996, Pages 247-252

  Zittoun, R ^a  

^a HÔTEL DIEU   (France)

Author keywords

Acute myelogenous leukemia; Bone marrow transplantation; Clinical trials

Indexed keywords

CYTARABINE; DAUNORUBICIN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOXANTRONE;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ALLOGENIC BONE MARROW TRANSPLANTATION; CANCER COMBINATION CHEMOTHERAPY; CANCER REGRESSION; CANCER SURVIVAL; CLINICAL TRIAL; HUMAN; MAJOR CLINICAL STUDY; REVIEW; TREATMENT OUTCOME;

EID: 0029784413     PISSN: 14302772     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00282-996-0247-x     Document Type: Review

References (17)

1. Baudard M, Marie JP, Cadiou M, Viguié F, Zittoun R (1994) Acute myelogeaous leukaemia in the elderly: retrospective study of 235 consecutive patients. Br J Haematol 86 : 82-91
2. Brincker H (1985) Estimate of overall treatment results in acute nonlymphocytic leukemia based on age-specific rates of incidence and complete remission. Cancer Treat Rep 69 : 5-11
3. Büchner Th, Urbanitz D, Hiddemann W, et al (1985) Intensified induction and consolidation with or without maintenance chemotherapy for acute myeloid leukemia (AML): two multicenter studies of the German AML cooperative group. J Clin Oncol 3 : 1583-1589
4. Cassileth PA, Lynch E, Hines JD, et al (1992) Varying intensity of postremission therapy in acute myeloid leukemia. Blood 79 : 1924-1930
5. Herman J, Suciu S, Stijnen Th, et al (1989) Treatment of acute myelogenous leukemia: an EBMT-EORTC retrospective analysis of chemotherapy versus allogeneic or autologous bone marrow transplantation. Eur J Cancer Clin Oncol 25 : 545-550
6. Löwenberg B, Zittoun R, Kerkhoffs H, et al (1989) On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: a randomized phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group. J Clin Oncol 7 : 1268-1274
7. Löwenberg B, Suciu S, Zittoun R, et al (1995) GM-CSF during as well as after induction chemotherapy (CT) in elderly patients with acute myeloid leukemia (AML). The EORTC-HOVON phase III trial (AML 11) (abstract). Blood 86 [Supp 1] : 433a
8. Mayer RJ, Davis RB, Schiffer CA, et al (1994) Intensive postremission chemotherapy in adults with acute myeloid leukemia. N Engl J Med 331 : 896-903
9. Rohatiner AZ, Gregory WM, Bassan R, et al (1988) Short-term therapy for acute myelogenous leukemia. J Clin Oncol 6 : 218-226
10. Suciu S (1991) The value of BMT in AML patients in first remission : a statician's view-point. Ann Hematol 62 : 41-44
11. de Witte Th, Suciu S, Boogaerts M, et al (1995) Intensive remission-induction chemotherapy followed by autologous or allogeneic stem cell transplantation (SCT) for high risk MDS and AML secondary to MDS (SAML) in patients < 60 years. A joint study of the EORTC Leukemia Group and the EBMT (abstract). Blood 86 [Suppl 1] : 618a
12. Wolff SN, Herzig RH, Fay JW, et al (1989) High-dose cytarabine and daunorubicin as consolidation therapy for acute myeloid leukemia in first remission: long-term follow-up and results. J Clin Oncol 7 : 1260-1267
13. Zittoun R, Jehn U, Fière D, et al (1989) Alternating v repeated postremission treatment in adult acute myelogenous leukemia: a randomized phase III study (AML 16) of the EORTC Leukemia Cooperative Group. Blood 73 : 896-906
14. Zittoun RA, Mandelli F, Willemze R, et al (1995) Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. N Engl J Med 332 : 217-223
15. Zittoun R, Suciu S, Solbu G, et al (1995) Comparison of quality of life (QOL) of patients with acute myelogenous leukemias (AML) in long-term first complete remission (CR) after bone marrow transplantation (BMT) - allogeneic or autologous - or intensive chemotherapy consolidation (ICC) : EORTC-GIMEMA AML 8A study (abstract). Blood 86 [Suppl 1] : 433a
16. Zittoun R, Liso V, Mandelli F, et al (1992) Intensive consolidation chemotherapy versus standard consolidation maintenance in acute myelogenous leukemia (AML) in first remission : an EORTC-GIMEMA phase III trial (AML 8 B). Leukemia 6 [Suppl 2] : 76-77
17. Zittoun R, Mandelli F, de Witte Th, et al (1994) Recombinant human granulocyte-macrophage colony stimulating factor (GM-CSF) during induction treatment of acute myelogenous leukemia (AML). A randomized trial from EORTC-GIMEMA cooperative groups (abstract). Blood 81 [Suppl 1] : 231a