Molecular basis of subcellular localization of HCV core protein

Liver

Volumn 16, Issue 4, 1996, Pages 221-224

  Suzuki, T ^a,b   Matsuura, Y ^a   Harada, T ^a   Suzuki, R ^a   Saito, I ^a   Miyamura, T ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

HCV core protein; Hepatitis C virus; Nuclear localization signal; Truncated core protein

Indexed keywords

CORE PROTEIN; VIRUS PROTEIN;

CELL CYCLE; CELLULAR DISTRIBUTION; HEPATITIS C; HEPATITIS C VIRUS; LIVER CELL CARCINOMA; MOLECULAR BIOLOGY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SHORT SURVEY; VIRUS GENOME;

EID: 0029783482     PISSN: 01069543     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0676.1996.tb00732.x     Document Type: Short Survey

References (35)

1. PARKIN D M, STJENSWARD J, MUIR C S. Estimates of the world-wide frequency of twelve major cancers. Bull WHO 1984: 62: 163-182.
2. TANAKA R, ITOSHIMA T, NAGASHIMA H. Follow-up study of 582 liver cirrhosis patients for 26 years in Japan. Liver 1987: 7: 316-324.
3. SAITO I, MIYAMURA T, OHBAYASHI A, et al. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci USA 1990: 87: 6547-6549.
4. CHOW W-H, YONEYAMA T, TAKEUCHI K, SAITO I, MIYAMURA T. Discrimination of hepatitis C virus in liver tissues from different patients with hepatocellular carcinomas by direct nucleotide sequencing of amplified cDNA of the viral genome. J Clin Microbiol 1991: 29: 2860-2864.
5. OHKOSHI S, KOJIMA H, TAWARAYA H, et al. Detection of hepatitis C virus RNA in sera and liver tissues of non-A, non-B hepatitis patients using the polymerase chain reaction. Jpn J Cancer Res 1990: 81: 862-865.
6. YONEYAMA T, TAKEUCHI K, WATANABE Y, et al. Detection of hepatitis C virus cDNA sequence by the polymerase chain reaction in hepatocellular carcinoma tissues. Jpn J Med Sci Biol 1990: 43: 89-94.
7. kB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 1989: 58: 227-229.
8. kB: homology to rel and dorsal. Cell 1990: 62: 1019-1029.
9. NASMYTH K, ADOLF G, LYDALL D, SEDDON A. The identification of a second cell cycle control on the HO promoter in yeast: cell cycle regulation of SW15 nuclear entry. Cell 1990: 62: 631-647.
10. VAN ETTEN R A, JACKSON P, BALTIMORE D. The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization. Cell 1989: 58: 669-678.
11. ROUX P, BLANCHARD J M, FERNANDEZ A, LAMB N, JEANTEUR P, PIECHACZYK M. Nuclear localization of c-fos, but not v-fos proteins, is controlled by extra cellular signals. Cell 1990: 63: 341-351.
12. GRAKOUI A, WYCHOWSKI C, LIN C, FEINSTONE S M, RICE C M. Expression and identification of hepatitis C virus polyprotein cleavage products. J Virol 1993: 67: 1385-1395.
13. HIJIKATA M, KATO N, OOTSUYAMA Y, NAKAGAWA M, SHIMOTOHNO K. Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc Natl Acad Sci USA 1991: 88: 5547-5551.
14. GRAKOUI A, MCCOURT D W, WYCHOWSKI C, FEINSTONE S M, RICE C M. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol 1993: 67: 2832-2843.
15. HIJIKATA M, MIZUSHIMA H, AKAGI T, et al. Two distinct proteinase activities required for the processing of a putative non-structural precursor protein of hepatitis C virus. J Virol 1993: 67: 4665-4675.
16. HARADA S, TAKEUCHI K, SUZUKI T, et al. Expression of processed core protein of hepatitis C virus in mammalian cells. J Virol 1991: 65: 3015-3021.
17. MATSUURA Y, HARADA S, SUZUKI R, et al. Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells. J Virol 1992: 66: 1425-1431.
18. MANABE S, FUKE I, TANISITA O, et al. Production of non-structual proteins of hepatitis C virus requires a putative viral protease encoded by NS3. Virology 1994: 198: 636-644.
19. SIMMONDS P, HOLMES E C, CHA T-A, et al. Clasification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenic analysis of the NS5 region. J Gen Virol 1993: 74: 2391-2399
20. OKAMOTO H, SUGIYAMA Y, OKADA S, et al. Hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 1992: 73: 673-679.
21. SUZUKI R, MATSUURA Y, SUZUKI T, et al. Nuclear localization of the truncated hepatitis C virus core protein deleted in its hydrophobic C-terminus. J Gen Virol 1995: 76: 53-61.
22. HARADA T. Establishment of human liver cell line constitutively expressing hepatitis C virus structural proteins. (manuscript in preparation).
23. SELBY M J, CHOO Q -L, BERGER K et al. Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome. J Gen Virol 1993: 74: 1103-1113.
24. LANFORD R E, NOTVALLL, CHAVEZ D, et al. Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells. Virology 1993: 197: 225-236.
25. SHIH C-M, LO S J, MIYAMURA T, CHEN S-Y, LEE Y-H W. Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells. J Virol 1993: 67: 5823-5832.
26. LO S-Y, SELBY M, TONG M, OU J-H. Comparative studies of the core gene products of two different hepatitis C virus isolates: two alternative forms determined by a single amino acid substitution. Virology 1994: 199: 124-131.
27. BULICH R, ASAKOV J G. Nuclear localization of dengue 2 virus core protein detected with monoclonal antibodies. J Gen Virol 1992: 73: 2999-3003.
28. CHOO Q -L, RICHMAN K H, HAN J H, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci USA 1991: 88: 2451-2455.
29. INCHAUSPE G, ZEBEDEE S, LEE D -H, SUGITANI M, NASOFF M, PRINCE A M, Genomic structure of the human prototype strain H of hepatitis C virus: comparison with the American and Japanese isolates. Proc Natl Acad Sci USA 1991: 88: 10292-10296.
30. KATO N, HIJIKATA M, OOTSUYAMA Y, et al. Molecalar cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci USA 1990: 87: 9524-9528.
31. TAKAMIZAWA AT, MORI C, FUKE L, Structure and organization of the hepatitis C virus genome isolated from human carriers. J Virol 1991: 65: 1105-1113.
32. OKAMOTO H, OKADA S, SUGIYAMA Y, et al. Nucleotide sequence of the genomic RNA of hepatitis C virus isolated from a human carrier: comparison with reported isolates for conserved and divergent regions. J Gen Virol 1991: 72: 2697-2704.
33. OKAMOTO H, KURAI K, OKADA S, et al. Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes. Virology 1992: 188: 331-341.
34. YEH C-T, WONG S W, FUNG Y K, OU J-H. Cell cycle regulation of nuclear localization of hepatitis B virus core protein. Proc Natl Acad Sci USA 1993: 90: 6459-6463.
35. 124 inhibits nuclear import of SV40 T antigen proteins. J Cell Biol 1991: 115: 1203-1211.