Activation of locus coeruleus somatostatin receptors induces an increase of growth hormone release in male rats

Journal of Neuroendocrinology

Volumn 8, Issue 10, 1996, Pages 761-764

  Mounier, Françoise ^a   Bluet Pajot, Marie Thérèse ^a   Moinard, Florence ^a   Kordon, Claude ^a   Epelbaum, Jacques ^a  

^a INSERM   (France)

Author keywords

Galanin; Growth hormone; Locus coeruleus; Rat; Somatostatin

Indexed keywords

GALANIN; GALANIN RECEPTOR; GROWTH HORMONE; OXIDOPAMINE; SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE RELEASE; LATERAL BRAIN VENTRICLE; LOCUS CERULEUS; MALE; NONHUMAN; NORADRENERGIC NERVE; PRIORITY JOURNAL; PULSATILE HORMONE RELEASE; RAT; RECEPTOR BINDING;

EID: 0029783429     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.1996.05115.x     Document Type: Article

References (21)

1. Jones BE, Halaris AE, Moore RY. Ascending projections of the LC in the rat: Axonal transport in central noradrenaline neurons; autoradiographic study. Brain Res 1977; 127: 1-53.
2. Koibuchi N, Kalo M, Kakegawa T et al. Electrical stimulation of specific brainstem nuclei suppresses GRF induced GH secretion in the pentobarbital anaesthetized rat. J Neuroendocri. 1989; 1: 209-214.
3. Bluet-Pajot MT, Mounier F, Durand D, et al. 6-Hydroxydopamine lesions of the locus coeruleus induce a paradoxical increase in growth hormone secretion in male rats. J Neurvendocri. 1992; 4: 9-14.
4. Abe H, Kato Y, Iwasaki Y, et al. Central effect of somatostatin on the secretion of growth hormone in the anesthetized rat. Proc Soc Exp Biol Med 1978; 159: 346.
5. Ottlecz A, Samson WK, McCann SM. Galanin: evidence for a hypothalamic site of action to release GH. Peptides 1986; 7: 51-53.
6. Melander T, Fuxe K, Harfstrand A. et al Effects of ICV injections of galanin on neuroendocrine functions in the male rat. Acta Physio Scand 1987; 131: 25-32.
7. Olpe HR, Steinmam MW, Pozza MF et al Comparative investigations on the actions of ACTH-24, SRIF, neurotensin, SP and vasopressin on LC neuronal activity in vitro. Naunym Schmiedeberg Arch Pharmaco 1987; 336: 434-437.
8. Inoue M, Nakajima S, Nakajima Y. SRIF induces an inward rectification in rat LC neurons through a pertussis sensitive mechanism. J Physiol 1988; 407: 177-198.
9. Seutin V, Verbanck P, Massotte L et al. Galanin decreases the activity of LC neurons in vitro. Eur J Pharmarco 1989; 164: 373-376.
10. Reubi JC, Maurer R. Autoradiographic mapping of somatostatin receptors in the rat CNS and pituitary. Neuroscience 1985; 15: 1183-1193.
11. Moyse E, Beaudet A, Bertherat J et al. Light microscopic autoradiographie localization of somatostatin binding sites in the brainstem of the rat. J Chem Neuroanat 1992; 5: 75-84.
12. 14 binding sites in the locus coeruleus of the rat are located in both ascending and descending projecting noradrenergic cells. Peptides 1990; 11: 21-27.
13. Melander T, Hökfelt T, Nilsson S, Brodin E. Visualization of galanin binding sites in the rat nervous system. Eur J Pharmacol 1986; 124: 381-382.
14. Loughlin SE, Foote SL, Bloom FE. Efferent projections of nucleus locus coeruleus: topographic organization of cells of origin demonstrated by three dimensional reconstructions. Neuroscience 1986: 18: 291-306.
15. Murakami Y, Kato Y, Kabayama Y et al. Involvement of hypothalamic GRF in GH secretion induced by ICV injection of somatostatin in rats. Endocrinology 1987; 120: 311.
16. Willoughby JO, Kapoor R. Intrahypothalamic injection of somatostatin, not GRF, stimulates prolactin secretion. Neuropeptide 1990; 15: 153-156.
17. Sutin E, Jacobowitz DM. Immunochemistry localization of peptides and other neurochemicals in the rat laterodorsal tegmental nucleus and adjacent area. J Camp Neural 1988; 270: 243-270.
18. Palkovits M, Epelbaum J, Tapia-Arancibia L. et al. Somatostatin in catecholamine-rich nuclei of the brainstem. Neuropeptides 1982; 3: 139-144.
19. Aston-Jones G, Ennis M, Pieribone VA. et al. The brain LC: restricted afferent control of broad efferent network. Science 1986; 234: 734-737.
20. Bluet-Pajot MT, Schaub C, Mounier F et al. Monoaminergic regulation of growth hormone in the rat. J Endocrinol 1980; 86: 387-396.
21. Niswender GD, Chen CL, Midgley AR et al. Radioimmunoassay for rat prolactin. Proc Soc Exp Biol Med 1969; 130: 793.