Antiphosphatidylethanolamine antibodies as the only antiphospholipid antibodies. I. Association with thrombosis and vascular cutaneous diseases

Journal of Rheumatology

Volumn 23, Issue 8, 1996, Pages 1369-1374

  Berard, Madeleine ^a,b   Chantome, Roland ^a   Marcelli, Aline ^a   Boffa, Marie Claire ^a  

^a INSERM   (France)

^b SAINT LOUIS HOSPITAL   (France)

Author keywords

Anticardiolipin antibodies; Autoimmune diseases; Livedo reticularis

Indexed keywords

PHOSPHATIDYLETHANOLAMINE ANTIBODY; PHOSPHOLIPID ANTIBODY; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; FEMALE; HUMAN; LIVEDO RETICULARIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; THROMBOSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, ANTIPHOSPHOLIPID; ANTIPHOSPHOLIPID SYNDROME; AUTOIMMUNE DISEASES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PHOSPHATIDYLETHANOLAMINES; SKIN DISEASES, VASCULAR; THROMBOSIS;

EID: 0029783366     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. McNeil HP, Chesterman CN, Krilis SA: Immunology and clinical importance of antiphospholipid antibodies. Adv Immunol 1991;49:193-280.
2. Soulier JP, Boffa MC: Avortements à répétition, thromboses et anticoagulant circulant de type antithromboplastine. Nouv Presse Méd 1980; 9:859-64.
3. Harris EN, Chan JK, Asherson RA, Aber VR, Gharavi AE, Hughes GR: Thrombosis, RFL and thrombocytopenia. Predictive value of the anticardiolipin antibody test. Arch Intern Med 1986; 146:2153-6.
4. Hughes G, Harris N, Gharavi A: The anticardiolipin syndrome. J Rheumatol 1986; 13:486-8.
5. Harris EN, Baguley E, Asherson RA, Hughes GRV: Clinical and serological features of the "antiphospholipid syndrome" (abstr). Br J Rheumatol 1987;(suppl 2)26:19.
6. Asherson RA, Khamashta MA, Ordi-Ros J: The "primary" antiphospholipid syndrome: Major clinical and serological features. Medicine 1989; 68:366-74.
7. Piette JC, Wechsler B, Bletry O, et al: Antiphospholipid syndrome. The clinician's point of view. Ann Méd Interne (Paris) 1992; 143:392-5.
8. Hughes GRV: The antiphospholipid syndrome: Ten years on. Lancet 1993; 7:341-4.
9. Harris EN, Hughes GRV: Standardizing the anticardiolipin antibody test (letter). Lancet 1987; 31:277.
10. Harris EN: The Second International Anticardiolipin Standardization Workshop. The Kingston antiphospholipid antibody study (KAPS) group. Am J Clin Pathol 1990; 94:476-84.
11. Gilman-Sachs A, Lubinski J, Beer AE, Brend S, Beaman KD: Patterns of antiphospholipid antibody specificities. J Clin Lab Immunol 1991; 35:83-8.
12. Alarcon-Segovia D, Cabral AR: Functional and immunochemical heterogeneity of antiphospholipid antibodies: A classification. J Rheumatol 1992; 198:1166-9.
13. Toschi V, Motta A, Castelli C, et al: Prevalence and clinical significance of antiphospholipid antibodies to non-cardiolipin antigens in systemic lupus erythematosus. Haemostasis 1993; 23:275-83.
14. Falcon CR, Hoffer AM, Carreras LO: Evaluation of the clinical and laboratory associations of antiphosphatidylethanolamine. Thromb Res 1990; 59:383-8.
15. Karmochkine M, Berard M, Piette JC, et al: Antiphosphatidylethanol amine antibodies in systemic lupus erythematosus. Lupus 1993; 2:157-60.
16. Vlachoyiannopoulos PG, Beigbeder G, Dueymes M, et al: Autoantibodies to phosphatidylethanolamine in antiphospholipid syndrome and systemic lupus erythematosus. Their correlation with anticardiolipin antibodies and B2 glycoprotein I plasma levels. Autoimmunity 1993; 16:245-9.
17. Nemerson Y: The phospholipid requirement of tissue factor in blood coagulation. J Clin Invest 1968; 47:72-80.
18. Pitlick FA, Nemerson Y: Binding of the protein component of tissue factor to phospholipids. Biochemistry 1970; 9:5105-13.
19. Galvin JB, Kurosawa S, Moore K, Esmon NL: Reconstitution of rabbit thrombomodulin into phospholipid vesicles. J Biol Chem 1987; 262:2199-205.
20. Smirnov MD, Esmon CT: Phosphatidylethanolamine incorporation into vesicles selectively enhances factor Va inactivation by activated protein C. J Biol Chem 1994; 269:816-9.
21. Smirnov MD, Triplett DT, Comp PC, Esmon NL, Esmon CT: On the role of phosphatidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies. J Clin Invest 1995;95:309-16.
22. Cabral AR, Cabiedes J, Alarcon-Segovia D, Sanchez-Guerrero J: Phospholipid specificity and requirement of β2-glycoprotein 1 for reactivity of antibodies from patients with primary antiphospholipid syndrome. J Autoimmun 1992; 5:787-801.
23. McNeil HP, Chesterman CN, Krilis SA: Binding specificity of lupus anticoagulants and anticardiolipin antibodies. Thromb Res 1988; 52:609-19.
24. Reber G, Tremblet C, Bernard C, Mermillod B, de Merloose P: Anticardiolipin antibodies and thrombosis: Buffer's influence on the detection and quantitation of anticardiolipin antibody measured by ELISA. Thromb Res 1990, 57:215-26.
25. Wagenknecht DR, Sugi T, McIntyre JA: The evolution, evaluation and interpretation of antiphospholipid antibody assays. Clin Immunol Newsletter 1995; 15:28-38.
26. Rosove MH, Brewer P: Antiphospholipid thrombosis: Clinical course after the first thrombotic event in 70 patients. Ann Intern Med 1992; 117:303-8.
27. Weidmann CE, Wallace DJ, Peter JB, Knight PJ, Bear MB, Klinenberg JR: Studies of IgG, IgM and IgA antiphospholipid antibody isotypes in systemic lupus erythematosus. J Rheumatol 1988; 15:74-9.
28. Qamar T, Gharavi AE, Levy RA, Lockshin MD: Lysophosphatidylethanolamine is the antigen to which apparent antibody to phosphatidylethanolamine binds. J Clin Immunol 1990; 10:200-3.
29. Karmochkine M, Cacoub P, Piette JC, Godeau P, Boffa MC: Antiphosphatidylethanolamine antibody as the sole antiphospholipid antibody in systemic lupus erythematosus with thrombosis. Case report. Clin Exp Rheumatol 1992; 10:603-5.
30. Loizou S, MacWorth-Young CG, Cofiner C, Walport MJ: Heterogeneity of binding reactivity to different phospholipids of antibodies from patients with systemic lupus erythematosus and with syphilis. Clin Exp Immunol 1990; 80:171-6.
31. Vlachoyiannopoulos PG, Krilis SA, Hunt JE, Manoussakis MN, Moutsopoulos HM: Patients with anticardiolipin antibodies with and without antiphospholipid syndrome: Their clinical features and B2-GP1 plasma levels. Eur J Clin Invest 1992; 22:482-7.
32. Grob JJ, Bonerandi JJ: Cutaneous manifestations associated with the presence of the lupus anticoagulant. J Am Acad Dermatol 1986; 15:211-9.
33. Staub HL, Harris EN, Khamashta MA, Savidge G, Chahade WH, Hughes GRV: Antibody to phosphatidylethanolamine in a patient with lupus anticoagulant and thrombosis. Ann Rheum Dis 1989; 48:166-9.
34. Karmochkine M, Berard M, Piette JC, Cacoub P, Godeau P, Boffa MC: The effect of sera with antiphospholipid antibodies on endothelial cell procoagulant activity is dependent upon the charge of the phospholipids against which they are directed. Thromb Res 1994; 74:435-40.
35. Allegre VA, Gastineau DA, Winkelmann RK. Skin lesions associated with circulating lupus anticoagulant. Br J Dermatol 1989; 120:419-29.
36. Stephens CJM: The antiphospholipid syndrome: Clinical correlations, cutaneous features, mechanism of thrombosis and treatment of patients with the lupus anticoagulant and anticardiolipin antibodies, Br J Dermatol 1991; 125:199-210.
37. Naldi L, Locati F, Marchesi L, et al: Cutaneous manifestations associated with antiphospholipid antibodies in patients with suspected primary antiphospholipid syndrome. A case control study. Ann Rheum Dis 1993; 52:219-22.
38. Weinstein C, Miller MH, Axtens R, Buchanan R, Littlejohn GO: Livedo reticularis associated with increased titers of anticardiolipin antibodies in systemic lupus erythematosus. Arch Dermatol 1987; 123:596-600.
39. Francès C, Tribout B, Boisnic S, et al: Cutaneous necrosis associated with the lupus anticoagulant. Dermatologica 1989; 178:194-20.
40. Dodd HJ, Sarkany I, O'Shaunessey D: Widespread cutaneous necrosis associated with the lupus anticoagulant. Clin Exp Dermatol 1985; 10:582-6.
41. Stephansson EA, Niemi KM, Jouhikainen T, Vaarala O, Palosuo T: Lupus anticoagulant and the skin. Acta Derm Venereal 1991; 71:416-22.
42. Boffa MC, Berard M, Sugi T, McIntyre JA: Antiphosphatidylethanolamine antibodies as the only antiphospholipid antibodies detected by ELISA: II. Kininogen reactivity. J Rheumatol 1996;23:1375-9.
43. Janoff AS, Rauch J: The structural specificity of anti-phospholipid antibodies in autoimmune disease. Chem Phys Lipids 1986; 40:315-32.