Detection of human herpes virus 6 in AIDS-associated retinitis by means of in situ hybridization, polymerase chain reaction and immunohistochemistry

Journal of Medical Virology

Volumn 49, Issue 4, 1996, Pages 289-295

  Fillet, Anne Marie ^a   Reux, Isabelle ^a   Joberty, Cathy ^a   Fournier, Jean Guy ^b   Hauw, Jean Jacques ^a   Le Hoang, Phuc ^a   Bricaire, François ^a   Huraux, Jean Marie ^a   Agut, Henri ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b HÔPITAL SAINT VINCENT DE PAUL   (France)

Author keywords

AIDS; CMV; HHV 6; HIV 1; Immunohistochemistry; In situ hybridization; PCR; Retinitis

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN HERPESVIRUS 6; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; OPPORTUNISTIC INFECTION; POLYMERASE CHAIN REACTION; RETINITIS; VIRUS DETECTION;

EID: 0029782718     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1096-9071(199608)49:4<289::aid-jmv6>3.3.co;2-n     Document Type: Article

References (40)

1. Agut H, Collandre H, Aubin JT, Guétard D, Favier V, Ingrand D, Montagnier L, Huraux JM (1989): In vitro sensitivity of human herpesvirus 6 to antiviral drugs. Research in Virology 140: 219-228.
2. Anderson RA, Liu DX, Macaulay HA, Gompels UA (1995): Definition of a betaherpesvirus specific gH domain required for gH/gL complex formation. 127. The XXth International Herpesvirus Workshop, July 29-August 3. Groningen, The Netherlands.
3. Aubin JT, Agut H, Collandre H, Yamanishi K, Chandran B, Montagnier L, Huraux JM (1993): Antigenic and genetic differentiation of the two putative types of human herpesvirus 6. Journal of Virological Methods 41:223-234.
4. Breese Hall C, Long CE, Schnabel KC, Caserta MT, McIntyre KM, Costanzo MA, Knott A, Dewhurst S, Insel RA, Epstein LG (1994): Human herpesvirus 6 infection in children. New England Journal of Medicine 331(7):432-438.
5. Caserta MT, Hall CB, Schnabel K, McIntyre K, Long C, Costanzo M, Dewhurst S, Insel R, Epstein LG (1994): Neuroinvasion and persistence of human herpesvirus 6 in children. Journal of Infectious Diseases 170:1586-1589.
6. Collandre H, Aubin JT, Agut H, Bechet JM, Montagnier L (1990): Detection of HHV-6 by the polymerase chain reaction. Journal of Virological Methods 31:171-180.
7. Cone RW, Hackman RC, Huang M-LW, Bowden RA, Meyers JD, Hetcalf M, Zeh J, Ashley R, Corey L (1993): Human herpesvirus 6 in lung tissue from patients with pneumonitis after bone marrow transplantation. New England Journal of Medicine 329:159-161.
8. Defer C, Agut H, Garbarg-Chenon A, Moncany M, Morinet F, Vignon D, Mariotti M, Lefrère JJ (1992): Multicentric quality control of polymerase chain reaction for detection of HIV DNA. AIDS 6: 659-663.
9. Fillet AM, Katlama C, Visse B, Camilleri S, Rogeaux O, Huraux JM (1993): Human CMV infection of the CNS: Concordance between PCR detection in CSF fluid and pathological examination. AIDS 7 (7):1016-1018.
10. Fillet AM, Raphael M, Visse B, Audouin J, Poirel L, Agut H, and French study group for HIV associated tumors (1995): A controlled study of human herpesvirus 6 detection in AIDS-associated non Hodgkin's lymphoma. Journal of Medical Virology 45:106-112.
11. Flamand L, Gosselin J, D'Addario M, Hiscott J, Ablashi DV, Gallo RC, Menezes J (1991): Human herpesvirus 6 induces interleukin-1 β and tumor necrosis factor alpha, but not interleukin-6, in peripheral blood mononuclear cell cultures. Journal of Virology 65: 5105-5110.
12. Flamand L, Gosselin J, Stefanescu I, Ablashi D, Menezes J (1995): Immunosuppressive effect of human herpesvirus 6 on T-cell functions: Suppression of interleukin-2 synthesis and cell proliferation. Blood 85:1263-1271.
13. Fox JD, Briggs M, Ward PA, Tedder RS (1990): Human herpesvirus 6 in salivary glands. Lancet 336:590-593.
14. Freeman WR, Lerner CW, Mines JA, Lash RS, Nadel AJ, Starr MB, Tapper ML (1984): A prospective study of ophthalmologic findings in the acquired immune deficiency syndrome. American Journal of Ophthalmology 97:133.
15. Gautheret A, Aubin JT, Poirel L, Chopineau S, Agut H, Dussaix E (1996): Detection and variant identification of HHV-6 by a non radioactive hybridization microplate assay for amplimers detection. Journal of Virological Methods 58:33-40.
16. Holland GN, Pepose JS, Pettis TH, Gottlieb MS, Yee RD, Foos RY (1983): Acquired immunodeficiency syndrome. Ophthalmology 90: 859.
17. Ishiguro N, Yamada S, Takahashi T, Takahashi Y, Togashi T, Okuno T, Yamanishi K (1990): Meningoencephalitis associated with HHV-6 related exanthem subitum. Acta Paediatrica Scandinavica 79: 987-989.
18. Kondo K, Kondo T, Okuno T, Takahashi M, Yamanishi K (1991): Latent human herpes virus 6 infection of human monocytes/macrophages. Journal of General Virology 72:1401-1408.
19. Krueger GRF, Wassermann K, De Clerck LS, Stevens WJ, Bourgeois N, Ablashi DV, Josephs SF, Balachandran N (1990): Latent herpesvirus-6 in salivary and bronchial glands. Lancet 336:1255-1256.
20. Jabs DA, Green WR, Fox R, Polk BF, Bartlett JG (1989): Ocular manifestations of acquired immunodeficiency syndrome. Ophthalmology 96:1092.
21. Laure F, Rouzioux C, Veber F, Jacomet C, Courgnaud V, Blanche S, Burgard M, Griscelli C, Brechot C (1988): Detection of HIV-1 DNA in infants and children by means of the polymerase chain reaction. Lancet ii:538.
22. Lawrence GL, Chee M, Craxton MA, Gompels UA, Honess RW, Barrell BG (1990): Human herpesvirus 6 is closely related to human cytomegalovirus. Journal of Virology 64:287-299.
23. McCaughey C, Gormley P, Connoly JH, Archer DB, Coyle PV (1993): Antibodies to rubella and human herpesvirus 6 in diverse retinal diseases. Journal of Infectious Diseases 167:1499-1500.
24. Mitchell SM, Fox JD, Tedder RS, Gazzard BG, Lightman S (1994): Vitreous fluid sampling and viral genome detection for the diagnosis of viral retinitis in patients with AIDS. Journal of Medical Virology 43:336-340.
25. Okuno T, Higashi K, Shiraki K, Yamanishi K, Takahashi M, Kokado Y, Ishibashi I, Takahara S, Sonoda T, Tanaka K, Baba K, Yabuuchi H, Kurata T (1990): Human herpesvirus 6 in renal transplantation. Transplantation 49:519-522.
26. Okuno T, Shao H, Asada H, Shiraki K, Takahashi M, Yamanishi K (1992): Analysis of human herpesvirus 6 glycoproteins recognized by monoclonal antibody OHV1. Journal of General Virology 73: 443-447.
27. Ou CH, Kwok S, Mitchell SW, Mack DH, Snisky JJ, Krebs JW, Feorino P, Warfield D, Schochetman G (1988): DNA amplification for direct detection of HIV-1 in DNA of peripheral blood mononuclear cells. Science 239:295-297.
28. Pomerantz PJ, Kwutzkes DR, De la Monte SM, Rota JR, Bauer AS, Albert D, Bor DH, Feldman EL, Schoolez RT, Hirsch MS (1987): Infection of the retina by immunodeficiency virus type I. New England Journal of Medicine 317:1643-1647.
29. Pruksananonda P, Hall CB, Insel RA, McIntyre K, Pelett PE, Long CE, Schnabel KC, Pincus PH, Stamey FR, Dambaugh TR, Stewart JA (1992): Primary human herpesvirus 6 infections in young children. New England Journal of Medicine 326:1445-1450.
30. Qavi HB, Green MT, Segall GK, Font RL (1989): Demonstration of HIV-1 and HHV-6 in AIDS-associated retinitis. Current Eye Research 8:379-387.
31. Qavi HB, Green MT, Segall GK, Lewis DE, Hollinger FB (1992): Transcriptional activity of HIV-1 and HHV-6 in retinal lesions from AIDS patients. Investigative Ophthalmology Visual Science 33: 2759-2767.
32. Qavi HB, Green MT, Lewis DE, Hollinger FB, Pearson G, Ablashi D (1994): Implication of HIV-1 and HHV-6 in the development of AIDS retinitis. (333B) Tenth International Conference on AIDS. Yokohama, Japan, 7-12 August.
33. Razzaque A, Jones C (1995): Characterization of a transactivator protein identified in the transforming domain ZVH14 of human herpesvirus-6: Activation of heterologous promoters including the H-RAS. 182. The XXth International Herpesvirus Workshop, July 29-August 3. Groningen, The Netherlands.
34. Reux I, Fillet AM, Agut H, Katlama C, Le Hoang P, Hauw JJ (1992): In situ detection of human herpes virus 6 in AIDS associated retinitis. American Journal of Ophthalmology 114(3):375-377.
35. Reux I, Fillet AM, Fournier JG, Agut H, Gentilini M, Le Hoang P, Hauw JJ (1993): In situ hybridization of HIV-1 RNA in retinal vascular wall. American Journal of Pathology 143:1275-1279.
36. Reux I, Fillet AM, Fournier JG, Joberty C, Agut H, Katlama C, LeHoang P, Hauw JJ (1996): Cytomegalovirus (CMV) and human immunodeficiency virus (HIV-1) detection in the retina. A controlled clinicopathological study using immunohistochemistry, in situ hybridization and DNA amplification. Current Eye Research (submitted).
37. Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, Mullis KB, Erlich HA (1987): Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487-491.
38. Salahuddin SZ, Ablashi DV, Markham PD, Josephs SF, Sturzenzgger S, Kaplan M, Halligan G, Biberfeld P, Wong-Staal F, Kramarsky B, Gallo RC (1986): Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. Science 234:596-600.
39. Suga S, Yoshikawa T, Asano Y, Kozawa T, Nakashima T, Kobayashi I, Yazaki T, Yamamoto H, Kajita Y, Ozaki T, Nishimura Y, Yamanaka T, Yamada A, Imanishi J (1993): Clinical and virological analyses of 21 infants with exanthem subitum and central nervous system complications. Annals of Neurology 33(6):597-603.
40. Yamanishi K, Shiraki K, Kondo T, Okuno T, Takahashi M, Asano Y, Kurata T (1988): Identification of human herpesvirus 6 as causal agent for exanthem subitum. Lancet i: 1065-1067.