Changing a leucine to a lysine residue makes NaeI endonuclease hypersensitive to DNA intercalative drugs

Biochemistry

Volumn 35, Issue 31, 1996, Pages 10014-10018

  Jo, Kiwon ^a   Topal, Michael D ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; ENDONUCLEASE; INTERCALATING AGENT;

AMINO ACID SUBSTITUTION; ARTICLE; COVALENT BOND; DNA CLEAVAGE; DNA PROTEIN COMPLEX; DNA STRAND; ENZYME ANALYSIS; PRIORITY JOURNAL;

AMSACRINE; ANTINEOPLASTIC AGENTS; BINDING SITES; DAUNORUBICIN; DEOXYRIBONUCLEASE ECORI; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA NUCLEOTIDYLTRANSFERASES; DNA TOPOISOMERASES, TYPE I; ELLIPTICINES; ENZYME INHIBITORS; INTEGRASES; INTERCALATING AGENTS; KINETICS; LYSINE; NALIDIXIC ACID; NOVOBIOCIN; OXOLINIC ACID; POINT MUTATION; RECOMBINANT PROTEINS; RECOMBINASES;

EID: 0029782653     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9604542     Document Type: Article

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