Multiparameter flow-cytometric analysis of bcl-2 and Fas expression in normal and neoplastic hematopoiesis

American Journal of Clinical Pathology

Volumn 106, Issue 3, 1996, Pages 345-351

  Digiuseppe, Joseph A ^a   Lebeau, Patti ^a   Augenbraun, Jeanne ^a   Borowitz, Michael J ^a,b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Apoptosis; bcl 2; Fas; Leukemia; Myelopoiesis

Indexed keywords

FAS ANTIGEN; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; FLOW CYTOMETRY; GRANULOCYTE; HEMATOPOIESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA; MONOCYTE; MYELOBLAST; MYELODYSPLASIA; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROLYMPHOCYTE; PROTEIN EXPRESSION;

EID: 0029782377     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/106.3.345     Document Type: Article

References (26)

1. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-1462.
2. Korsmeyer SJ. bcl-2 initiates a new category of oncogenes: Regulators of cell death. Blood 1992;80:879-886.
3. Nagata S, Golstein P. The Fas death factor. Science 1995;267: 1449-1456.
4. Rieux-Laucat F, Le Diest F, Hivroz C, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995;268:1347-1349.
5. Lotem J, Sachs L. Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy comounds in differentiation-competent and -defective myeloid leukemic cells. Cell Growth Differ 1993;4:41-47.
6. Sachs L, Lotem J. Control of programmed cell death in normal and leukemic cells: New implications for therapy. Blood 1993;82:15-21.
7. Campos L, Rouault J-P, Sabido O, et al. High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy. Blood 1993;81:3091-3096.
8. Zutter M, Hockenberry D, Silverman GA, Korsmeyer SJ. Immunolocalization of the bcl-2 protein within hematopoietic neoplasms. Blood 1991;78:1062-1068.
9. Delia D, Aiello A, Soligo D, et al. bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells. Blood 1992;79: 1291-1298.
10. Porwitt-MacDonald A, Ivory K, Wilkinson S, et al. bcl-2 protein expression in normal human bone marrow precursors and in acute myelogenous leukemia. Leukemia 1995;9:1191-1198.
11. Miyawaki T, Uehara T, Ryuhtaro N, et al. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 1992;149:3753-3758.
12. Iwai K, Miyawaki T, Takenori T, et al. Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils. Blood 1994;84:1201-1208.
13. Debatin K-M, Goldman CK, Waldmann TA, Krammer PH. APO-1-induced apoptosis of leukemia cells from patients with adult T-cell leukemia. Blood 1993;81:2972-2977.
14. Moller P, Henne C, Leithauser F, et al. Coregulation of the APO-1 antigen with intercellular adhesion molecule-1 (CD54) in tonsillar B cells and coordinate expression in follicle center and mediastinal B-cell lymphomas. Blood 1993;81:2067-2075.
15. Munker R, Lubbert M, Yonehara S, et al. Expression of the Fas antigen on primary human leukemia cells. Ann Hematol 1995;70:15-17.
16. Komada Y, Zhou Y-W, Zhang X-L, et al. Fas receptor (CD95)-mediated apoptosis is induced in leukemic cells entering G1B compartment of the cell cycle. Blood 1995;86:3848-3860,
17. Borowitz MJ, Guenther KL, Shults KE, Stelzer GT. Immunophenotyping of acute leukemia by flow cytometric analysis: Use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis. Am J Clin Pathol 1993;100:534-540.
18. Campana D, Coustan-Smith E, Manabe A, et al. Prolonged survival of B-lineage acute lymphoblastic leukemia cells is accompanied by overexpression of bcl-2 protein. Blood 1993;81:1025-1031.
19. Merino R, Ding L, Veis DJ, et al. Developmental regulation of the bcl-2 protein and susceptibility to cell death in B lymphocytes. EMBO J 1994;13:683-691.
20. Hockenberry DH, Zutter M, Hickey W, et al. bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci USA 1991;88:6961-6965.
21. Bradbury D, Zhu Y-M, Russell N. Regulation of bcl-2 expression and apoptosis in acute myeloblastic leukemia cells by granulocyte-macrophage colony-stimulating factor. Leukemia 1994;8: 786-791.
22. Ratanatharathorn V, Uberti J, Karanes C, et al. Prospective comparative trial of autologous versus allogeneic bone marrow transplantation in patients with non-Hodgkin's lymphoma. Blood 1994;84:1050-1055.
23. Horowitz MM, Gale RP, Sondel PM, et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990;75: 555-562.
24. Nagafuji K, Shibuya T, Harada M, et al. Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells. Blood 1995;86:883-889.
25. Itoh N, Tsujimoto Y, Nagata S. Effect of bcl-2 on Fas antigen-mediated cell death. J Immunol 1993;151:621-627.
26. Yoshino T, Kondo E, Cao L, et al. Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes. Blood 1994;83:1856-1861.