Regulation of fibroblast proliferation in three-dimensional collagen gel matrix

In Vitro Cellular and Developmental Biology - Animal

Volumn 32, Issue 7, 1996, Pages 427-433

  Mio, Tadashi ^a   Adachi, Yuichi ^a   Romberger, Debra J ^a   Ertl, Ronald F ^a   Rennard, Stephen I ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

collagen gel; fibroblast; proliferation; wound repair

Indexed keywords

COLLAGEN GEL;

ARTICLE; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; LUNG FIBROBLAST;

EID: 0029781718     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02723005     Document Type: Article

References (18)

1. Bell, E.; Ivarsson, B.; Merrill, C. Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc. Natl. Acad. Sci. USA 76:1274-1278; 1979.
2. Bellows, G. G.; Melcher, A. H.; Aubin, J. E. Contraction and organization of collagen gels by cells cultured from periodontal ligament, gingiva and bone suggest functional differences between cell types. J. Cell Sci. 50:299-314; 1981.
3. Ehrmann, R. I.; Gey, G. O. The growth of cells on a transparent gel of reconstituted rat-tail collagen. J. Natl. Cancer Inst. 16:1375-1403; 1956.
4. Elsdale, T.; Bard, J. Collagen substrata for studies on cell behavior. J. Cell Biol. 54:626-637; 1972.
5. Grinnell, F. Fibroblasts, myofibroblasts, and wound contraction (minireview on the cellular mechanisms of disease). J. Cell Biol. 124:401-404; 1994.
6. Grinnell, F.; Bennett, M. H. Fibroblast adhesion on collagen substrata in the presence and absence of plasma fibronectin. J. Cell Sci. 48:19-34; 1981.
7. Labarca, C.; Paigen, K. A simple, rapid, and sensitive DNA assay procedure. Anal. Biochem. 102:344-352; 1980.
8. Lin, Y. C.; Grinnell, F. G. Decreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices. J. Cell Biol. 122:663; 1993.
9. Mauch, C.; Adelmann, G. B.; Hatamochi, A., et al. Collagenase gene expression in fibroblasts is regulated by a three-dimensional contact with collagen. FEBS Lett. 250:301-305; 1989.
10. Mochitate, K.; Pawelek, P.; Grinnell, F. Stress relaxation of contracted collagen gels: disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis. Exp. Cell Res. 193:198-207; 1991.
11. Nakagawa, S.; Pawelek, P.; Grinnell, F. Extracellular matrix organization modulates fibroblast growth and growth factor responsiveness. Exp. Cell Res. 182:572-582; 1989.
12. Nakagawa, S.; Pawelek, P.; Grinnell, F. Long-term culture of fibroblasts in contracted collagen gels: effects on cell growth and biosynthetic activity. J. Invest. Dermatol. 93:792-798; 1989.
13. Nishiyama, T.; Horii, I.; Nakayama, Y., et al. A distinct characteristic of the quiescent state of human dermal fibroblasts in contracted collagen gel as revealed by no response to epidermal growth factor alone, but a positive growth response to a combination of the growth factor and saikosaponin b1. Matrix 10:412-419; 1990.
14. Nishiyama, T.; Tsunenaga, M.; Nakayama, Y., et al. Growth rate of human fibroblasts is repressed by the culture within reconstituted collagen matrix but not by the culture on the matrix. Matrix 9:193-199; 1989.
15. Nusgens, B.; Merrill, C.; Lapiere, C. M., et al. Collagen biosynthesis by cells in a tissue equivalent matrix in vitro. Collagen Relat. Res. 4:351-364; 1984.
16. Sarber, R.; Hull, B.; Merrill, C., et al. Regulation of proliferation of fibroblasts of low and high population doubling levels grown in collagen lattices. Mech. Ageing Devel. 17:107-117; 1981.
17. Schor, S. L. Cell proliferation and migration on collagen substrata in vitro. J. Cell Sci. 41:159-175; 1980.
18. Tomasek, J. J.; Hay, E. D.; Fujiwara, K. Collagen modulates cell shape and cytoskeleton of embryonic corneal and fibroma fibroblasts: distribution of actin, alpha-actinin, and myosin. Dev. Biol. 92:107-122; 1982.