메뉴 건너뛰기




Volumn 120, Issue 1, 1996, Pages 82-91

Conserved histidine residues of RCC1 are essential for nucleotide exchange on Ran

Author keywords

Alanine scanning; mantGDP; Ran; RanGEF; RCC1

Indexed keywords

ALANINE; CHROMOSOME PROTEIN; GUANINE NUCLEOTIDE; HISTIDINE;

EID: 0029781628     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021397     Document Type: Article
Times cited : (31)

References (37)
  • 2
    • 0024445582 scopus 로고
    • The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA
    • Ohtsubo, M., Ozaki, H., and Nishimoto, T. (1989) The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J. Cell Biol. 109, 1389-1397
    • (1989) J. Cell Biol. , vol.109 , pp. 1389-1397
    • Ohtsubo, M.1    Ozaki, H.2    Nishimoto, T.3
  • 3
    • 0022731944 scopus 로고
    • Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation
    • Kai, R., Ohtsubo, M., Sekiguchi, M., and Nishimoto, T. (1986) Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation. Mol. Cell. Biol. 6, 2027-2032
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2027-2032
    • Kai, R.1    Ohtsubo, M.2    Sekiguchi, M.3    Nishimoto, T.4
  • 5
    • 0025734777 scopus 로고
    • Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis
    • Nishitani, H., Ohtsubo, M., Yamashita, K., Iida, H., Pines, J., Yasuda, H., Shibata, Y., Hunter, T., and Nishimoto, T. (1991) Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis. EMBO J. 10, 1555-1564
    • (1991) EMBO J. , vol.10 , pp. 1555-1564
    • Nishitani, H.1    Ohtsubo, M.2    Yamashita, K.3    Iida, H.4    Pines, J.5    Yasuda, H.6    Shibata, Y.7    Hunter, T.8    Nishimoto, T.9
  • 6
    • 0025195105 scopus 로고
    • A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation
    • Bischoff, F.R., Maier, G., Tilz, G., and Ponstingl, H. (1990) A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation. Proc. Natl. Acad. Sci. USA 87, 8617-8621
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8617-8621
    • Bischoff, F.R.1    Maier, G.2    Tilz, G.3    Ponstingl, H.4
  • 7
    • 0025856292 scopus 로고
    • The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homologue of the vertebrate gene regulator of chromosome condensation, RCC1
    • Frasch, M. (1991) The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homologue of the vertebrate gene regulator of chromosome condensation, RCC1. EMBO J. 10, 1225-1236
    • (1991) EMBO J. , vol.10 , pp. 1225-1236
    • Frasch, M.1
  • 8
    • 0024676037 scopus 로고
    • Yeast pheromone response pathway: Characterization of a suppressor that restores mating to receptorless mutants
    • Clark, K.L. and Sprague, G.F. (1989) Yeast pheromone response pathway: Characterization of a suppressor that restores mating to receptorless mutants. Mol. Cell. Biol. 9, 2682-2694
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2682-2694
    • Clark, K.L.1    Sprague, G.F.2
  • 9
    • 0025149080 scopus 로고
    • A yeast mutant, prp20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation
    • Aebi, M., Clark, M.W., Vijayraghavan, U., and Abelson, J. (1990) A yeast mutant, prp20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation. Mol. Gen. Genet. 224, 72-80
    • (1990) Mol. Gen. Genet. , vol.224 , pp. 72-80
    • Aebi, M.1    Clark, M.W.2    Vijayraghavan, U.3    Abelson, J.4
  • 10
    • 0027182286 scopus 로고
    • Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily
    • Kadowaki, T., Goldfarb, D., Spitz, L.M., Tartakoff, A.M., and Ohno, M. (1993) Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. EMBO J. 12, 2929-2937
    • (1993) EMBO J. , vol.12 , pp. 2929-2937
    • Kadowaki, T.1    Goldfarb, D.2    Spitz, L.M.3    Tartakoff, A.M.4    Ohno, M.5
  • 11
    • 0025789103 scopus 로고
    • Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase
    • Matsumoto, T. and Beach, D. (1991) Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase. Cell 66, 347-360
    • (1991) Cell , vol.66 , pp. 347-360
    • Matsumoto, T.1    Beach, D.2
  • 12
    • 0028009578 scopus 로고
    • A fission yeast RCC1-related protein is required for the mitosis to interphase transition
    • Sazer, S. and Nurse, P. (1994) A fission yeast RCC1-related protein is required for the mitosis to interphase transition. EMBO J. 13, 606-615
    • (1994) EMBO J. , vol.13 , pp. 606-615
    • Sazer, S.1    Nurse, P.2
  • 13
    • 0025735606 scopus 로고
    • Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S. cerevisiae
    • Ohtsubo, M., Yoshida, T., Seino, H., Nishitani, H., Clark, K., Sprague, G., Frasch, M., and Nishimoto, T. (1991) Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S. cerevisiae. EMBO J. 10, 1265-1273
    • (1991) EMBO J. , vol.10 , pp. 1265-1273
    • Ohtsubo, M.1    Yoshida, T.2    Seino, H.3    Nishitani, H.4    Clark, K.5    Sprague, G.6    Frasch, M.7    Nishimoto, T.8
  • 14
    • 0026232855 scopus 로고
    • The yeast SRM1 protein and human RCC1 protein share analogous functions
    • Clark, K.L., Ohtsubo, M., Nishimoto, T., Goebl, M., and Sprague, G.F. (1991) The yeast SRM1 protein and human RCC1 protein share analogous functions. Cell Regul. 2, 781-792
    • (1991) Cell Regul. , vol.2 , pp. 781-792
    • Clark, K.L.1    Ohtsubo, M.2    Nishimoto, T.3    Goebl, M.4    Sprague, G.F.5
  • 15
    • 0025784095 scopus 로고
    • Analysis of yeast prp20 mutations and functional complementation by the human homologue RCC1, a protein involved in the control of chromosome condensation
    • Fleischmann, M., Clark, W.M., Forrester, W., Wickens, M., Nishimoto, T., and Aebi, M. (1991) Analysis of yeast prp20 mutations and functional complementation by the human homologue RCC1, a protein involved in the control of chromosome condensation. Mol. Gen. Genet. 227, 417-423
    • (1991) Mol. Gen. Genet. , vol.227 , pp. 417-423
    • Fleischmann, M.1    Clark, W.M.2    Forrester, W.3    Wickens, M.4    Nishimoto, T.5    Aebi, M.6
  • 16
    • 0026419320 scopus 로고
    • Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1
    • Bischoff, F.R. and Ponstingl, H. (1991) Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature 354, 80-82
    • (1991) Nature , vol.354 , pp. 80-82
    • Bischoff, F.R.1    Ponstingl, H.2
  • 17
    • 0027376308 scopus 로고
    • The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
    • Moore, M.S. and Blobel, G. (1993) The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature 365, 661-663
    • (1993) Nature , vol.365 , pp. 661-663
    • Moore, M.S.1    Blobel, G.2
  • 19
    • 0026726128 scopus 로고
    • Defects in mRNA 3′-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: Possible coupling of mRNA processing and chromatin structure
    • Forrester, W., Stutz, F., Rosbash, M., and Wickens, M. (1992) Defects in mRNA 3′-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: Possible coupling of mRNA processing and chromatin structure. Genes Dev. 6, 1914-1926
    • (1992) Genes Dev. , vol.6 , pp. 1914-1926
    • Forrester, W.1    Stutz, F.2    Rosbash, M.3    Wickens, M.4
  • 20
    • 0028102739 scopus 로고
    • Loss of RCC1 leads to suppression of nuclear protein import in living cells
    • Tachibana, T., Imamoto, N., Seino, H., Nishimoto, T., and Yoneda, Y. (1994) Loss of RCC1 leads to suppression of nuclear protein import in living cells. J. Biol. Chem. 269, 24542-24545
    • (1994) J. Biol. Chem. , vol.269 , pp. 24542-24545
    • Tachibana, T.1    Imamoto, N.2    Seino, H.3    Nishimoto, T.4    Yoneda, Y.5
  • 21
    • 0028355757 scopus 로고
    • Effects of mutant Ran/TC4 proteins on cell cycle progression
    • Ren, M., Coutavas, E., D'Eustachio, P., and Rush, M. (1994) Effects of mutant Ran/TC4 proteins on cell cycle progression. Mol. Cell Biol. 14, 4216-4224
    • (1994) Mol. Cell Biol. , vol.14 , pp. 4216-4224
    • Ren, M.1    Coutavas, E.2    D'Eustachio, P.3    Rush, M.4
  • 22
    • 0027058705 scopus 로고
    • Chromosome condensation caused by loss of RCC1 function required the cdc25C protein that is located in the cytoplasm
    • Seki, T., Yamashita, K., Nishitani, H., Takagi, T., Russell, P., and Nishimoto, T. (1992) Chromosome condensation caused by loss of RCC1 function required the cdc25C protein that is located in the cytoplasm. Mol. Biol. Cell 3, 1373-1388
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1373-1388
    • Seki, T.1    Yamashita, K.2    Nishitani, H.3    Takagi, T.4    Russell, P.5    Nishimoto, T.6
  • 23
    • 0026026818 scopus 로고
    • The GTPase superfamily: Conserved structure and molecular mechanism
    • Bourne, H.R., Sanders, D.A., and McCormick, F. (1991) The GTPase superfamily: Conserved structure and molecular mechanism. Nature 349, 117-127
    • (1991) Nature , vol.349 , pp. 117-127
    • Bourne, H.R.1    Sanders, D.A.2    McCormick, F.3
  • 24
    • 0024403619 scopus 로고
    • High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
    • Cunningham, B.C. and Wells, J.A. (1989) High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. Science 244, 1081-1085
    • (1989) Science , vol.244 , pp. 1081-1085
    • Cunningham, B.C.1    Wells, J.A.2
  • 25
    • 0017803272 scopus 로고
    • Analysis of a method for selecting temperature sensitive mutants of BHK cells
    • Nishimoto, T. and Basillico, C. (1978) Analysis of a method for selecting temperature sensitive mutants of BHK cells. Somatic Cell Genet. 4, 323-340
    • (1978) Somatic Cell Genet. , vol.4 , pp. 323-340
    • Nishimoto, T.1    Basillico, C.2
  • 26
    • 2642699794 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel, T.A. (1985) Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82, 488-492
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 488-492
    • Kunkel, T.A.1
  • 27
    • 0025044647 scopus 로고
    • Cloning of Xenopus RCC1 cDNA, a homologue of the human RCC1 gene: Complementation of tsBN2 mutation and identification of the product
    • Nishitani, H., Kobayashi, H., Ohtsubo, M., and Nishimoto, T. (1990) Cloning of Xenopus RCC1 cDNA, a homologue of the human RCC1 gene: Complementation of tsBN2 mutation and identification of the product. J. Biochem. 107, 228-235
    • (1990) J. Biochem. , vol.107 , pp. 228-235
    • Nishitani, H.1    Kobayashi, H.2    Ohtsubo, M.3    Nishimoto, T.4
  • 28
    • 0027938043 scopus 로고
    • A mutant form of Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation
    • Dasso, M., Seki, T., Azuma, Y., Ohba, T., and Nishimoto, T. (1994) A mutant form of Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation. EMBO J. 13, 5732-5744
    • (1994) EMBO J. , vol.13 , pp. 5732-5744
    • Dasso, M.1    Seki, T.2    Azuma, Y.3    Ohba, T.4    Nishimoto, T.5
  • 29
    • 0020674810 scopus 로고
    • New ribose-modified fluorescent analogs of adenine and guanine nucleotides available as substrates for various enzymes
    • Hiratsuka, T. (1983) New ribose-modified fluorescent analogs of adenine and guanine nucleotides available as substrates for various enzymes. Biochim. Biophys. Acta 742, 496-508
    • (1983) Biochim. Biophys. Acta , vol.742 , pp. 496-508
    • Hiratsuka, T.1
  • 30
    • 0026693262 scopus 로고
    • DNA-binding domain of RCC1 protein is not essential for coupling mitosis with DNA replication
    • Seino, H., Hisamoto, N., Uzawa, S., Sekiguchi, T., and Nishimoto, T. (1992) DNA-binding domain of RCC1 protein is not essential for coupling mitosis with DNA replication. J. Cell Sci. 102, 393-400
    • (1992) J. Cell Sci. , vol.102 , pp. 393-400
    • Seino, H.1    Hisamoto, N.2    Uzawa, S.3    Sekiguchi, T.4    Nishimoto, T.5
  • 31
    • 0028132028 scopus 로고
    • Site-directed mutagenesis of the yeast PRP20/ SRM1 gene reveals distinct activity domains in the protein product
    • Lee, A., Clark, K.L., Fleischmann, M., Aebi, M., and Clark, M.W. (1994) Site-directed mutagenesis of the yeast PRP20/ SRM1 gene reveals distinct activity domains in the protein product. Mol. Gen. Genet. 245, 32-44
    • (1994) Mol. Gen. Genet. , vol.245 , pp. 32-44
    • Lee, A.1    Clark, K.L.2    Fleischmann, M.3    Aebi, M.4    Clark, M.W.5
  • 33
    • 0025836659 scopus 로고
    • Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide
    • Bischoff, F.R. and Ponstingl, H. (1991) Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide. Proc. Natl. Acad. Sci. USA 88, 10830-10834
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10830-10834
    • Bischoff, F.R.1    Ponstingl, H.2
  • 35
    • 0028964821 scopus 로고
    • Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1
    • Klebe, C., Bischoff, F.R., Ponstingl, H., and Wittinghofer, A. (1995) Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1. Biochemistry 34, 639-647
    • (1995) Biochemistry , vol.34 , pp. 639-647
    • Klebe, C.1    Bischoff, F.R.2    Ponstingl, H.3    Wittinghofer, A.4
  • 36
    • 0028801195 scopus 로고
    • The kinetic mechanism of Ran-nucleotide exchange catalyzed by RCC1
    • Klebe, C., Prinz, H., Wittinghofer, A., and Goody, R.S. (1995) The kinetic mechanism of Ran-nucleotide exchange catalyzed by RCC1. Biochemistry 34, 12543-12552
    • (1995) Biochemistry , vol.34 , pp. 12543-12552
    • Klebe, C.1    Prinz, H.2    Wittinghofer, A.3    Goody, R.S.4
  • 37
    • 0028934834 scopus 로고
    • Human RanGTPase-activating protein Ran GAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport
    • Bischoff, F.R., Krebber, H., Kemp, T., Hermes, I., and Ponstingl, H. (1995) Human RanGTPase-activating protein Ran GAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport. Proc. Natl. Acad. Sci. USA 92, 1749-1753
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1749-1753
    • Bischoff, F.R.1    Krebber, H.2    Kemp, T.3    Hermes, I.4    Ponstingl, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.