Why do immunoassays for tumour markers give differing results? A view from the UK National External Quality Assessment Schemes

European Journal of Clinical Chemistry and Clinical Biochemistry

Volumn 34, Issue 9, 1996, Pages 755-759

  Sturgeon, Catharine M ^a   Seth, John ^a  

^a ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; PEPTIDE HORMONE; TUMOR MARKER;

ANTIBODY SPECIFICITY; AUTOMATION; CALIBRATION; CONFERENCE PAPER; HORMONE BLOOD LEVEL; HUMAN; IMMUNOASSAY; PRIORITY JOURNAL; QUALITY CONTROL; REFERENCE VALUE; TECHNIQUE;

ANTIBODY SPECIFICITY; CHORIONIC GONADOTROPIN; GREAT BRITAIN; HUMANS; IMMUNOASSAY; QUALITY CONTROL; REFERENCE VALUES; TUMOR MARKERS, BIOLOGICAL;

EID: 0029781312     PISSN: 09394974     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (10)

1. Seth J, Sturgeon CM, Al-Sadie R, Manning I, Ellis AR. External quality assessment of immunoassays of peptide hormones and tumour markers: principles and practice. Ann 1st Super Sanita 1991; 27:359-64.
2. Stenman U-H, Bidart J-M, Birken S, Mann K, Nisula B, O'Connor J. Standardization of protein immunoprocedures. Choriogonadotropin (CG). Scand J Clin Lab Invest 1993; 53 Suppl 216:42-78.
3. National Institute for Biological Standards and Control Catalogue (available from Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, UK), April, 1994.
4. Seth J, Sturgeon CM, Ellis AR. UK NEQAS for Peptide Hormones and Related Substances. Annual Review 1994.
5. Zucchelli GC, Pilo A, Chiesa MR, Masini S, Baccini C. Minimizing between-kit variability in immunoassay for carcinoembryonic antigen by use of a common standard. Clin Chem 1986; 32:1942-3.
6. Sturgeon CM, Seth J, Al-Sadie R. UK NEQAS for CEA and hCG: Improving performance? In: Sturgeon CM, Seth J, Middle JG, Halloran SP, editors. Proceedings of the UK NEQAS Endocrinology Meeting; 1994 Apr 11-14, Edinburgh UK, 1995:214-8.
7. Bormer O. Major disagreements between immunoassays of carcinoembryonic antigen may be caused by nonspecific crossreacting antigen 2 (NCA-2). Clin Chem 1991; 37:1736-9.
8. Pettersson K, Ding YQ, Huhtaniemi I. Monoclonal antibodybased discrepancies between two-site immunometric test systems for lutropin. Clin Chem 1992; 37:1745-8.
9. Ekins RP. Immunoassay standardization. Scand J Clin Eab Invest 1993; 53 Suppl 205:33-46.
10. Ekins RP, Chu FW. Multianalyte microspot immunoassay microanalytical "compact disk" of the future. Clin Chem 1991; 37:1955-67.