Improved designs for dose escalation studies using pharmacokinetic measurements

Statistics in Medicine

Volumn 15, Issue 15, 1996, Pages 1605-1618

  Piantadosi, Steven ^a   Liu, Guanghan ^b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ARTICLE; CLINICAL TRIAL; DOSE RESPONSE; DRUG DOSE; PHARMACOKINETICS; PROBABILITY; TIME;

AREA UNDER CURVE; BAYES THEOREM; CLINICAL TRIALS, PHASE I; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEASIBILITY STUDIES; HUMANS; LIKELIHOOD FUNCTIONS; LOGISTIC MODELS; MATHEMATICAL COMPUTING; MODELS, BIOLOGICAL; PHARMACOKINETICS; RESEARCH DESIGN;

EID: 0029780751     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0258(19960815)15:15<1605::AID-SIM325>3.0.CO;2-2     Document Type: Article

References (11)

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