Discharge properties of brain stem neurons projecting to the flocculus in the alert cat. I. Medial vestibular nucleus

Journal of Neurophysiology

Volumn 76, Issue 3, 1996, Pages 1759-1774

  Cheron, Guy ^a   Escudero, Miguel ^b   Godaux, Emile ^b  

^a UNIVERSITY OF MONS   (Belgium)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALERTNESS; ANIMAL EXPERIMENT; ANTIDROMIC STIMULATION; ARTICLE; BRAIN STEM; CAT; CEREBELLUM FLOCCULUS; ELECTRODE; EYE MOVEMENT; EYE POSITION; IMPLANTATION; MALE; NERVE CONDUCTION; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; VESTIBULAR NUCLEUS; VESTIBULOOCULAR REFLEX;

EID: 0029780743     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1996.76.3.1759     Document Type: Article

References (78)

1. ALLEY, K., BAKER, R., AND SIMPSON, I. Afferents to the vestibulo-cerebellum and the origin of the visual climbing fibers in the rabbit brain. Brain Res. 98: 582-589, 1975.
2. BALAND, J. F., GODAUX, E., AND CHERON, G. Algorithms for the analysis of the nystagmic eye movements induced by sinusoidal head rotations. IEEE. Trans. Biomed. Eng. BME 34: 811-816, 1987.
3. BARMACK, N. H., BAUGHMAN, R. W., ERRICO, P., AND SHOJAKU, H. Vestibular primary afferent projection to the cerebellum of the rabbit. J. Comp. Neurol. 327: 521-534, 1993.
4. HERMAN, A. L. The Brain Stem of the Cat. A Cytoarchitectomic Atlas With Stereotaxic Coordinates. Madison, WI: Univ. of Wisconsin Press, 1968.
5. BERTHOZ, A., DROULEZ, J., VIDAL, P. P., AND YOSHIDA, Y. Neural correlates of horizontal vestibulo-ocular reflex cancellation during eye movements in the cat. J. Physiol. Lond. 419: 719-751, 1989.
6. BERTHOZ, A., YOSHIDA, K., AND VIDAL, P. P. Horizontal eye movement signals in second-order vestibular nuclei neurons in the cat. In: Vestibular and Oculomotor Physiology, edited by B. Cohen. New York: New York Acadamy of Sciences, 1981, part III, p. 144-156.
7. BIZZI, E., POMPEIANO, O., AND SOMOGGI, I. Spontaneous activity of single vestibular neurons of unrestrained cats during sleep and wakefulness. Arch. Ital. Biol. 102: 308-330, 1964.
8. BLANKS, R. H. I., ESTES, M. J., AND MARKHAM, C. H. Physiologic characteristics of vestibular first-order canal neurons in the cat. II. Response to constant angular acceleration. J. Neurophysiol. 38: 1250-1268, 1975.
9. BLANKS, R. H. I., PRECHT, W., AND TORIGOE, Y. Afferent projections to the cerebellar flocculus in the pigmented rat demonstrated by retrograde transport of horseradish peroxidase. Exp. Brain Res. 52: 293-306, 1983.
10. BRODAL, A. AND BRODAL, P. Observations on the secondary vestibulocerebellar projections in the macaque monkey. Exp. Brain Res. 58: 62-74, 1985.
11. CULLEN, K. AND MCCREA, R. A. Firing behavior of brain stem neurons during voluntary cancellation of the horizontal vestubuloocular reflex. I. Secondary vestibular neurons. J. Neurophysiol. 70: 828-843, 1993.
12. DELGADO-GARCIA, J. M., DEL Pozo, F., AND BAKER, R. Behavior of neurons in the abducens nucleus of the alert cat. I. Motoneurones. Neuroscience 17: 929-952, 1986.
13. DELGADO-GARCIA, J. M., VIDAL, P. P., GOMEZ, C., AND BERTHOZ, A. A neruophysiological study of prepositus hypoglossi neurons projecting to oculomotor and preoculomotor nuclei in the alert cat. Neuroscience 29: 291-307, 1989.
14. DUENSING, F. AND SCHAEFER, K. P. Die Aktivität Einzelmer neurone im Bereich der Vestibulariskerne bei horizontal-Beschleinigung der Vestibular Nystagmus. Arch. Psychiatr. Nervenkr. 198: 225-252, 1958.
15. ECCLES, J. M., ITO, M., AND SZENTAGOTHAI, J. The Cerebellum as a Neuronal Machine. New York: Springer-Verlag, 1967.
16. EPEMA, A. H., GERRITS, N. M., AND VOOGD, J. Secondary vestibulocerebellar projections to the flocculus and uvulo-nodular lobule of the rabbit: a study using HRP and double fluorescent tracer techniques. Exp. Brain Res. 80: 72-82, 1990.
17. ESCUDERO, M., CHERON, G., AND GODAUX, E. Discharge properties of brain stem neurons projecting to the flocculus in the alert cat. II. Prepositus hypoglossi nucleus. J. Neurophysiol. 76: 1775-1785, 1996.
18. ESCUDERO, M., DE LA CRUZ, R. R., AND DELGADO-GARCIA, J. M. A physiological study of vestibular and prepositus hypoglossi neurones projecting to the abducens in the alert cat. J. Physiol. Lond. 458: 539-560, 1992.
19. ESCUDERO, M. AND DELGADO-GARCIA, J. M. Behavior of reticular, vestibular and prepositus neurons terminating in the abducens nucleus of the alert cat. Exp. Brain Res. 71: 218-222, 1988.
20. EZURE, K., SCHOR, R. H., AND YOSHIDA, K. The response of horizontal semicircular canal afferents to sinusoidal rotation in the cat. Exp. Brain Res. 33: 27-39, 1978.
21. FUCHS, A. F. AND KIMM, J. Unit activity nucleus of the alert monkey during horizontal angular acceleration and eye movement. J. Neurophysiol. 38: 1140-1161, 1975.
22. FUCHS, A. F. AND ROBINSON, D. A. A method for measuring horizontal and vestibular eye movement chronically in the monkey. J. Appl. Physiol. 21: 1068-1070, 1966.
23. GERRITS, N. M., EPEMA, A. H., VAN LINGE, A., AND DALM, E. The primary vestibulocerebellar projection in the rabbit: absence of primary afferents in the flocculus. Neurosci. Lett. 105: 27-33, 1989.
24. GERRITS, N. M., EPEMA, A. H., AND VOOGD, J. The mossy fiber projection of the nucleus reticularis tegmenti pontis to the flocculus and adjacent ventral paraflocculus in the cat. Neuroscience 11: 627-644, 1984.
25. GERRITS, N. M. AND VOOGD, J. The climbing fiber projection to the flocculus and adjacent paraflocculus in the cat. Neuroscience 1: 2971-2991, 1982.
26. GERRITS, N. M., VOOGD, J., AND MAGRAS, I. N. Vestibular afferents of the inferior olive and the vestibular-olivo-cerebellar climbing fiber pathway to the flocculus in the cat. Brain Res. 332: 325-336, 1985.
27. GODAUX, E. AND CHERON, G. Testing the common neural integrator hypothesis at a level of the individual abducens motoneurones in the alert cat. J. Physiol. Lond. 469 : 549-570, 1993.
28. GODAUX, E. AND CHERON, G. The hypothesis of the uniqueness of the oculomotor neural integrator: direct experimental evidence in the cat. J. Physiol. Lond. 492.2: 517-527, 1996.
29. GOULD, B. B. Organization of afferents from the brain stem nuclei to the cerebellar cortex in the cat. In: Advances in Anatomy Embryology and Cell Biology. Berlin: Springer-Verlag, 1980, vol. 62, 90 pp.
30. GRAF, W., SIMPSON, J. I., AND LEONARD, C. S. Spatial organisation of visual messages of the rabbit's cerebellar flocculus. II. Complex and simple spike responses of Purkinje cells. J. Neurophysiol. 60: 2091-2121, 1988.
31. HENN, V., BALSH, R. W., AND HEPP, K. The sleep-wake transition in the oculomotor system. Exp. Brain Res. 54: 166-176, 1984.
32. HIKOSAKA, O., IGUSA, Y., AND IMAI, H. Inhibitory connections of nystagmus-related reticular burst neurons with neurons in the abducens, prepositus hypoglossi and vestibular nuclei in the cat. Exp. Brain Res. 39: 301-311, 1980.
33. ITO, M. The Cerebellum and Neural Control. New York: Raven, 1984, p. 354-388.
34. ITO, M., NISIMARU, N., AND YAMAMOTO, M. Specific patterns of neuronal connections involved in the control of the rabbit's vestibulo-ocular reflex by the cerebellar flocculus. J. Physiol. Lond. 265: 833-854, 1977.
35. JUDGE, S. J., RICHMOND, B. J., AND CHU, F. C. Implantation of magnetic search coils for measurement of eye position: an improved method. Vision Res. 20: 535-538, 1980.
36. KELLER, E. L. AND KAMATH, B. Y. Characteristics of head rotation and eye movement related neurons in alert monkey vestibular nucleus. Brain Res. 100: 182-187, 1975.
37. KELLER, E. L. AND PRECHT, W. Adaptive modification of central vestibular neurons in the response to visual stimulation through reversing prims. J. Neurophysiol. 42: 896-911, 1979.
38. KING, W. M., LISBERGER, S. G., AND FUCHS, A. F. Responses of fibers in medial longitudinal fasciculus (MLF) of alert monkeys during horizontal and vertical conjugate eye movements evoked by vestibular or visual stimuli. J. Neurophysiol. 39: 1135-1149, 1976.
39. KOTCHABHAKDI, N. AND WALBERG, F. Primary vestibular afferent projections to the cerebellum as demonstrated by retrograde axonal transport of horseradish peroxidase. Brain Res. 142: 142-146, 1978a.
40. KOTCHABHAKDI, N. AND WALBERG, F. Cerebellar afferent projections from the vestibular nuclei in the cat: an experimental study with the method of retrograde axonal transport of horseradish peroxidase. Exp. Brain Res. 31: 591-604, 1978b.
41. LANGER, T., FUCHS, A. F., CHUBB, M. C., SCUDDER, C. A., AND LISBERGER, S. G. Floccular efferents in the rhesus macaque as revealed by autoradiography and horseradish peroxydase. J. Comp. Neurol. 235: 26-37, 1985a.
42. LANGER, T., FUCHS, A. F., SCUDDER, C. A., AND CHUBB, M. C. Afferents to the flocculus of the cerebellum in the rhesus macaque as revealed by retrograde transport of horseradish peroxydase. J. Comp. Neurol. 235: 1-25, 1985b.
43. LEONARD, C. S., SIMPSON, J. I., AND GRAF, W. Spatial organisation of visual messages of the rabbit's cerebellar. I. Typology of inferior olive neurons of the dorsal cap of kooy. J. Neurophysiol. 60: 2073-2090, 1988.
44. LIPSKY, J. Antidromic activation of neurones as an analytical tool in the study of the central nervous system. J. Neurosci. Methods 4: 1-33, 1981.
45. LISBERGER, S. G. AND FUCHS, A. F. Role of primate flocculus during rapid behavioral modification of vestibuloocular reflex. II. Mossy fiber firing patterns during horizontal head rotation and eye movement. J. Neurophysiol. 41: 764-778, 1978.
46. LISBERGER, S. G. AND MILES, F. A. Role of primate medial vestibular nucleus in long-term adaptive plasticity of vestibuloocular reflex. J. Neurophysiol. 43: 1725-1745, 1980.
47. LLINAS, R. AND HILLMAN, D. E. Physiological and morphological organisation of the cerebellar circuits in various vertebrates. In: Neurobiology of Cerebellar Evolution and Development, edited by R. Llinas. Chicago, IL: Institute for Biomedical Research, 1969, p. 43-73.
48. McCREA, R. A., YOSHIDA, Y., BERTHOZ, A., AND BAKER, R. Eye movement related activity and morphology of second order vestibular neurons terminating in the cat abducens nucleus. Brain Res. 40: 468-473, 1980.
49. McFARLAND, J. L. AND FUCHS, A. F. Discharge patterns in nucleus prepositus hypoglossi and adjacent medial vestibular nucleus during horizontal eye movement in behaving macaques. J. Neurophysiol. 68: 319-336, 1992.
50. MILES, F. A., FULLER, J. H., BRAITMAN, D. J., AND Dow, B. M. Long term adaptative changes in primate vestibuloocular reflex. III. Electrophysiological observations in flocculus of normal monkeys. J. Neurophysiol. 43: 1437-1476, 1980.
51. NODA, H. Mossy fibers sending retinal-slip, eye, and head velocity signals to the flocculus of the monkey. J. Physiol. Lond. 379: 39-60, 1986.
52. NODA, H. AND SUZUKI, D. A. The role of the flocculus of the monkey in saccadic eye movements. J. Neurophysiol. 294: 317-334, 1979a.
53. NODA, H. AND SUZUKI, D. A. The role of the flocculus of the monkey in fixation and smooth pursuit eye movement. J. Physiol. Lond. 294: 335-348, 1979b.
54. NODA, H. AND SUZUKI, D. A. Processing of eye movement signals in the flocculus of the monkey. J. Physiol. Lond. 294: 349-364, 1979c.
55. NODA, H. AND WARABI, T. Discharges of Purkinje cells in monkey's flocculus during smooth-pursuit eye movements and visual stimulus movements. Exp. Neurol. 93: 390-403, 1986.
56. OSCARSSON, O. Functional units of the cerebellum. Saggital zones and microzones. Trends Neurosci. 2: 143-145, 1979.
57. POLA, J. AND ROBINSON, D. A. Oculomotor signals in medial longitudinal fasciculus of the monkey. J. Neurophysiol. 41: 245-259, 1978.
58. ROBINSON, D. A. Oculomotor control signals. In: Basic Mechanisms of Ocular Mobility and Their Clinical Implications, edited by P. Bach-y-Rita and G. Lennestrand. Oxford, UK: Pergamon, 1975, vol. 24, p. 337-374.
59. SATO, Y., KANDA, K., AND KAWASAKI, T. Target neurons of floccular middle zone inhibition in medial vestibular nucleus. Brain Res. 446: 225-235, 1988.
60. SATO, Y. AND KAWASAKI, T. Functional localization in the three floccular zones related to eye movement control in the cat. Brain Res. 290: 25-31, 1984.
61. SATO, Y. AND KAWASAKI, T. Target neurons of floccular caudal zone inhibition in Y-group nucleus of vestibular nucleus complex. J. Neurophysiol. 57: 460-480, 1987.
62. SATO, Y. AND KAWASAKI, T. Operational unit responsible for plane specific control of eye movement by cerebellar floccular in cat. J. Neurophysiol. 64: 551-564, 1990.
63. SATO, Y. AND KAWASAKI, T. Identification of the Purkinje cell/climber fiber zone and its target neurons responsible for eye-movement control by the cerebellar flocculus. Brain Res. Rev. 16: 39-64, 1991.
64. SATO, Y., KAWASAKI, T., AND IKARASHI, K. Zonal organisation of the floccular Purkinje cells projecting to the vestibular nucleus in cat. Brain Res. 232: 1-15, 1982.
65. SATO, Y., KAWASAKI, T., AND IKARASHI, K. Afferent projections from the brain stem to the three floccular zones in cats. I. Climbing fiber projections. Brain Res. 212: 27-36, 1983a.
66. SATO, Y., KAWASAKI, T., AND IKARASHI, K. Afferent projections from the brain stem to the three floccular zones in cats. II. Mossy fiber projections. Brain Res. 272: 37-48, 1983b.
67. SCUDDER, C. A. AND FUCHS, A. F. Physiological and behaviorial identification of vestibular nucleus neurons mediating the horizontal vestibuloocular reflex in trained monkeys. J. Neurophysiol. 68: 244-264, 1992.
68. STAHL, J. S. AND SIMPSON, J. I. Floccular contribution to signal processing in the rabbit vestibular nucleus. Ann. NY Acad. Sci. 656: 181-189, 1992.
69. STONE, L. S. AND LISBERGER, S. G. Visual responses of Purkinje cells in the cerebellar flocculus during smooth-pursuit eye movements in monkeys. I. Simple spikes. J. Neurophysiol. 63: 1241-1261, 1990.
70. TAN, H. AND GERRITS, N. M. Laterality in the vestibulo-cerebellar mossy fiber projection to flocculus and caudal vermis in the rabbit: a retrograde fluorescent double-labeling study. Neuroscience 47: 909-919, 1992.
71. TAN, J., EPEMA, A. H., AND VOOGD, J. Zonal organization ofthe flocculovestibular nucleus projection in the rabbit: a combined axonal tracing and acetylcholinesterase histochemical study. J. Comp. Neurol. 356: 51-71, 1995.
72. TOMLINSON, R. D. AND ROBINSON, D. A. Signals in vestibular nucleus mediating vertical eye movements in the monkey. J. Neurophysiol. 51: 1121-1136, 1984.
73. WAESPE, W., BUTTNER, V., AND HENN, V. Visual-vestibular interaction in the flocculus of the alert monkey. I. Input activity. Exp. Brain Res. 43: 337-348, 1981.
74. WAESPE, W. AND HENN, V. Visual-vestibular interaction in the flocculus of the alert monkey. II. Purkinje cell activity. Exp. Brain Res. 43: 349-360, 1981.
75. YAMAMOTO, M. Topographical representation in rabbit cerebellar flocculus for various afferent input from the brain stem investigated by means of retrograde axonal transport of horseradish peroxidase. Neurosci. Lett. 12: 29-34, 1979.
76. YOSHIDA, K., BERTHOZ, A., VIDAL, P. P., AND McCREA, R. Eye movement related activity of identified second order vestibular neurons in the cat. In: Progress in Oculomotor Research, edited by A. Fuchs and W. Becker. Amsterdam: Elsevier/North-Holland, 1981, vol. 12, p. 371-378.
77. ZHANG, Y., PARTSALIS, A. M., AND HIGHSTEIN, S. M. Properties of superior vestibular nucleus neurons. Projecting to the cerebellar flocculus in the squirrel monkey. J. Neurophysiol. 69: 642-645, 1993.
78. ZHANG, Y., PARTSALIS, A. M., AND HIGHSTEIN, S. M. Properties of superior vestibular nucleus flocculus target neurons in the squirrel monkey. I. General properties in comparison with flocculus projecting neurons. J Neurophysiol. 73: 2261-2278, 1995.