Two antitumour ruthenium(III) complexes showing selectivity in their binding towards poly(dG)·poly(dC) and poly(dA)·poly(dT)

Chemical Communications

Volumn , Issue 15, 1996, Pages 1741-1742

  Hartmann, Markus ^a   Einhäuser, Thorsten J ^a   Keppler, Bernhard K ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; NUCLEIC ACID BASE; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); POLY[DEOXY(CYTIDYLATE GUANYLATE)]; RUTHENIUM COMPLEX; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; COVALENT BOND; DNA BINDING; DRUG BINDING;

EID: 0029780521     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/CC9960001741     Document Type: Article

References (17)

1. B. K. Keppler, M. Henn, U. M. Juhl, M. R. Berger, R. Niebl and F. E. Wagner. Progr. Clin. Biochem. Med., 1989, 10, 41.
2. B. K. Keppler, W. Rupp, U. M. Juhl, H. Endres, R. Niebl and W. Balzer, Inorg. Chem., 1987, 26, 4366.
3. O. M. Ni Dhubhghaill, W. R. Hagen, B. K. Keppler, K.-G. Lipponer and P. J. Sadler, J. Chem. Soc., Dalton Trans., 1994, 3305.
4. F. Kratz, M. Hartmann, B. K. Keppler and L. Messori, J. Biol. Chem., 1994, 269, 2381.
5. F. Kratz, B. K. Keppler, L. Messori, C. Smith and E. N. Baker, Metal-Based Drugs, 1994, 1, 169.
6. E. Holler, W. Schaller and B. K. Keppler, Arzneim.-Forsch./Drugs Res. 1991, 41, 1065.
7. M. L. McLaughlin, J. M. Cronan Jr., T. R. Schaller and R. D. Snelling, J. Am. Chem. Soc., 1990, 112, 8949.
8. H. L. Puhl and M. J. Behe, J. Mol. Biol., 1995, 245, 559; J. E. Herrera and J. B. Chaires, Biochemistry, 1989, 28, 1993.
9. H. L. Puhl and M. J. Behe, J. Mol. Biol., 1995, 245, 559; J. E. Herrera and J. B. Chaires, Biochemistry, 1989, 28, 1993.
10. S. S. Chan, K. J. Breslauer, M. E. Hogan, D. J. Kessler, R. H. Austin, J. Ojemann, J. M. Passner and N. C. Wiles, Biochemistry, 1990, 29, 6161.
11. J. Chatlas, R. van Eldik and B. K. Keppler, Inorg. Chim. Acta, 1995, 233, 59.
12. M. Hartmann PhD Thesis, Universität Heidelberg, 1996, p. 27.
13. P. T. Manoharan, P. K. Mehrotra, M. M. Taquikhan and R. K. Andall, Inorg. Chem., 1973, 12, 2753.
14. V. Brabec, M. Síp and M. Leng, Biochemistry, 1993, 32, 11676; D. Bancroft, C. A. Lepre and S. J. Lippard, J. Am. Chem. Soc., 1990, 112, 6860; A. Eastman, Biochemistry, 1986, 25, 3912.
15. V. Brabec, M. Síp and M. Leng, Biochemistry, 1993, 32, 11676; D. Bancroft, C. A. Lepre and S. J. Lippard, J. Am. Chem. Soc., 1990, 112, 6860; A. Eastman, Biochemistry, 1986, 25, 3912.
16. V. Brabec, M. Síp and M. Leng, Biochemistry, 1993, 32, 11676; D. Bancroft, C. A. Lepre and S. J. Lippard, J. Am. Chem. Soc., 1990, 112, 6860; A. Eastman, Biochemistry, 1986, 25, 3912.
17. R. D. Wells, J. E. Larson, R. C. Grant, B. E. Shortle and C. R. Cantor, J. Mol. Biol., 1970, 54, 465.