Effects of bile salt hydrophobicity on crystallization of cholesterol in model bile

European Journal of Clinical Investigation

Volumn 26, Issue 7, 1996, Pages 602-608

  Van Erpecum, K J ^a,c   Portincasa, P ^a,b   Gadellaa, M ^a   Van De Heijning, B J M ^a   Van Berge Henegouwen, G P ^a   Renooij, W ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Bile; bile salts; cholesterol; crystal shape; crystallization; hydrophobicity

Indexed keywords

BILE SALT; CHOLESTEROL; PHOSPHOLIPID; TAUROCHOLIC ACID; TAURODEOXYCHOLIC ACID;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; GALLSTONE FORMATION; HYDROPHOBICITY; PRIORITY JOURNAL; ULTRACENTRIFUGATION;

EID: 0029780501     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.1996.1910532.x     Document Type: Article

References (35)

1. Holan KR, Holzbach RT, Hermann RE, Cooperman AM, Claffey WJ. Nucleation time: a key factor in the pathogenesis of cholesterol gallstone disease. Gastroenterology 1979;77:611-17.
2. Halpern Z, Dudley MA, Lynn MP, Nader JM, Breuer C, Holzbach RT. Vesicle aggregation in model systems of supersaturated bile: relation to crystal nucleation and lipid composition of the vesicular phase. J Lipid Res 1986;27:295-306.
3. Konikoff FM, Chung DS, Donovan JM, Small DM, Carey MC. Filamentous, helical, and tubular microstructures during cholesterol crystallization from bile. J Clin Invest 1992;90:1155-60.
4. Konikoff FM, Cohen DE, Carey MC. Phospholipid molecular species influence crystal habits and transition sequences of metastable intermediates during cholesterol crystallization from bile salt-rich model bile. J Lipid Res 1994;35:60-70.
5. Wang DO-H, Carey MC. The complete mapping of cholesterol crystal nucleation paths in model and native bile. Gastroenterology 1994;106:A1004.
6. Halpern Z, Dudley MA, Kibe A, Lynn MP, Breuer AC, Holzbach RT. Rapid vesicle formation and aggregation in abnormal human biles. A time-lapse video-enhanced contrast microscopy study. Gastroenterology 1986;90:875-85.
7. van Erpecum KJ, Stolk MFJ, van den Broek AMWC, Renooij W, van de Heijning BJM, van Berge Henegouwen GP. Bile concentration promotes nucleation of cholesterol monohydrate crystals by increasing the cholesterol concentration in the vesicles. Eur J Clin Invest 1993;23:283-8.
8. Stolk MFJ, van de Heijning BJM, van Erpecum KJ, van den Broek AMWC, Renooij W, van Berge Henegouwen GP. The effect of bile acid hydrophobicity on nucleation of several types of cholesterol crystals from model bile vesicles. J Hepatol 1994; 20:802-10.
9. Kibe A, Dudley MA, Halpern Z, Lynn MP, Breuer AC, Holzbach RT. Factors influencing cholesterol monohydrate nucleation time in model systems of supersaturated bile. J Lipid Res 1985;26:1102-11.
10. Carey MC. Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res 1978;19:845-55.
11. Groen AK, Ottenhof R, Jansen PLM, van Marie J, Tijtgat GNJ. Effect of cholesterol nucleation-promoting activity on cholesterol solubilisation in model bile. J Lipid Res 1989;30:51-8.
12. Turley SD, Dietschy JM. Reevaluation of the 3-hydroxy-steroid dehydrogenase assay for total bile acids in bile. J Lipid Res 1978; 19:945-55.
13. Allain CC, Poon LS, Chan CSG, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. J Clin Chem 1974;20:470-5.
14. Gurantz D, Laker MF, Hofmann AF. Enzymatic measurement of choline containing phospholipids in bile. J Lipid Res 1981;22: 373-6.
15. Armitage P, Berry G. Statistical Methods in Medical Research. Oxford: Blackwell Scientific Publications, 1987.
16. van Erpecum KJ, van Berge Henegouwen GP, Stoelwinder B, Stolk MFJ, Eggink WF, Govaert WHA. Cholesterol and pigment gallstone disease: comparison of the reliability of three bile tests for differentiation between the two stone types. Scand J Gastroenterol 1988;23:948-54.
17. van Erpecum KJ, Portincasa P, Stolk MFJ et al. Effects of bile salt and phospholipid hydrophobicity on lithogenicity of human gallbladder bile. Eur J Clin Invest 1994;24:744-50.
18. Angelico M, Corradini SG, Masella R, Alvaro D, Cantafora A, Capocaccia L. Molecular composition of phosphatidylcholines. as related to cholesterol saturation, transport and nucleation in human-gallbladder bile. J Hepatol 1992;15:59-66.
19. Heuman R, Norrby S, Sjödahl R, Tiselius HG, Tagesson C. Altered gallbladder bile composition in gallstone disease. Relation to gallbladder wall permeability. Scand J Gastroenterol 1980;15:581-6.
20. Marcus SN, Heaton KW. Deoxycholic acid and the pathogenesis of gall stones. Gut 1988;29:522-33.
21. Berr F, Pratschke E, Fischer S, Paumgartner G. Disorders of bile acid metabolism in cholesterol gallstone disease. J Clin Invest 1992;90:859-68.
22. Shoda J, He B-F, Tanaka N et al. Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstone disease and its correlation with de novo syntheses of cholesterol and bile acids in liver, gallbladder emptying, and small intestinal transit. Hepatology 1995;21:1291-302.
23. Berr F, Mayer M, Sackmann M, Sauerbruch T, Holl J, Paumgartner G. Pathogenetic factors in early recurrence of cholesterol gallstones. Gastroenterology 1994;106:215-24.
24. Hussaini SH, Pereira SP, Murphy GM, Dowling RH. Deoxycholic acid influences cholesterol solubilization and microcrystal nucleation time in gallbladder bile. Hepatology 1995;22:1735-44.
25. Hussaini SH, Murphy GM, Kennedy C, Besser GM, Wass JAH, Dowling RH. The role of bile composition and physical chemistry in the pathogenesis of octreotide-associated gallbladder stones. Gastroenterology 1994;107:1503-13.
26. Hirota I, Chijiiwa K, Noshiro H, Nakayama F. Effect of chenodeoxycholate and ursodeoxycholate on nucleation lime in human gallbladder bile. Gastroenterology 1992;102:1668-74.
27. van Erpecum KJ, Portincasa P, Eckhardt E, Go PMNYH, van Berge-Henegouwen GP, Groen AK. Ursodeoxycholic acid reduces protein levels and nucleation-promoting activity in gallbladder bile. Gastroenterology 1996;110:1225-37.
28. Noshiro H, Chijiiwa K, Makino I, Hirota I. Deoxycholic acid in gall bladder does not account for the shortened nucleation time in patients with cholesterol gall stones. Gut 1995;36:121-5.
29. Makino I, Chijiiwa K, Higashijima H et al. Rapid cholesterol nucleation and cholesterol gall stone formation after subtotal or total colectomy in humans. Gut 1994;35:1760-4.
30. Donovan JM, Timofeyeva N, Carey MC. Cholesterol monohydrate (ChM) and liquid crystal formation in model biles: effects of bile salt (BS) hydrophobicity and phosphatidylcholine (PC) contents. Hepatology 1989;10:598A.
31. Juste C, Catala I, Henry R et al. Influence of bile salt molecular species on cholesterol crystallization from supersaturated model biles. Biochim Biophys Acta 1995;1254:89-97.
32. Portincasa P, van Erpecum KJ, Jansen A, Renooij W, Gadellaa M, van Berge-Henegouwen GP. Nucleation behaviour of various cholesterol crystals in bile from gallstone patients. Hepatology 1996;23:738-48.
33. Ahrendt SA, Fox-Talbot K, Kaufman HS, Lillemoe KD, Pitt HA. Cholesterol nucleates rapidly from mixed micelles in the prairie dog. B.B.A. 1994;1211:7-13.
34. Holzbach RT. Recent progress in understanding cholesterol crystal nucleation as a precursor to human gallstone formation. Hepatology 1986;6:1403-6.
35. Heuman DM, Bajaj R. Ursodeoxycholate conjugates protect against disruption of cholesterol-rich membranes by bile salts. Gastroenterology 1994;106:1333-41.