Riluzole anesthesia: Use-dependent block of presynaptic glutamate fibers

Anesthesiology

Volumn 85, Issue 3, 1996, Pages 626-634

  MacIver, M Bruce ^a   Amagasu, Shanti M ^b   Mikulec, Anthony A ^c   Monroe, Frances A ^b  

^a Stanford Anesthesia ^*  (United States)

^b STANFORD UNIVERSITY   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anesthetics: thiopental; Animals: rats; Brain: hippocampus, CA 1; cortex; cortical; Neurophysiology: action potential; conduction; postsynaptic; nerve; sodium channel; Pharmacology: aminobutyric acid; depressant; glutamate; hypnotic; narcotic; riluzole; Synapse: excitation; inhibition; transmission

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; RILUZOLE; SODIUM CHANNEL; THIOPENTAL;

ACTION POTENTIAL; ARTICLE; DEPRESSION; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPNOSIS; NERVE CONDUCTION; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL;

EID: 0029780307     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199609000-00023     Document Type: Article

References (36)

1. Pocock G, Richards CD: Cellular mechanisms in general anaesthesia. Br J Anaesth 1991; 66:116-28
2. Yamamura T, Harada K, Okamura A, Kemmotsu O: Is the site of action of ketamine anesthesia the N-methyl-D-aspartate receptor? ANESTHESIOLOGY 1990; 72:704-10
3. Daniell LC: The noncompetitive N-methyl-D-aspartate antagonists, MK-801, phencyclidine and ketamine, increase the potency of general anesthetics. Pharmacol Biochem Behav 1990; 36:111-5
4. Landau EM, Richter J, Cohen S: Differential solubilities in subregions of the membrane: A nonsteric mechanism of drug specificity. J Med Chem 1979; 22:325-7
5. Kendig JJ, MacIver MB, Roth SH: Anesthetic actions in the hippocampal formation. Ann N Y Acad Sci 1991; 625:37-53
6. Perouansky M, Baranov D, Salman M, Yaari Y: Effects of halothane on glutamate receptor-mediated excitatory postsynaptic currents. ANESTHESIOLOGY 1995; 83:109-19
7. A receptor/chloride channel complex in anesthesia. ANESTHESIOLOGY 1993; 78:757-76
8. A receptor channels. Annu Rev Neurosci 1994; 17:569-602
9. Schlame M, Hemmings HC: Inhibition by volatile anesthetics of endogenous glutamate release from synaptosomes by a presynaptic mechanism. ANESTHESIOLOGY 1995; 82:1406-16
10. Cheramy A, Barbeito L, Godeheu G, Glowinski J: Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo. Neurosci Lett 1992; 147:209-12
11. Martin D, Thompson MA, Nadler JV: The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. Eur J Pharmacol 1993; 250:473-6
12. Mantz J, Cheramy A, Thierry AM, Glowinski J, Desmonts JM: Anesthetic properties of riluzole (54274 RP), a new inhibitor of glutamate neurotransmission. ANESTHESIOLOGY 1992; 76:844-8
13. Benoit E, Escande D: Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre. Pflugers Arch 1991; 419:603- 9
14. Debono MW, Le Guern J, Canton T, Doble A, Pradier L: Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes. Eur J Pharmacol 1993; 235:283-9
15. Hebert T, Drapeau P, Pradier L, Dunn RJ: Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole. Mol Pharmacol 1994; 45:1055-60
16. Malgouris C, Daniel M, Dohle A: Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices. Neurosci Lett 1994; 177:95-9
17. Mantz J, Laudcnbach V, Lecharny JB, Henzel D, Desmonts JM: Riluzole, a novel antiglutamate, blocks GABA uptake by striatal synaptosomes. Eur J Pharmacol 1994; 257:R7-8
18. Ebling WF, Mills-Williams L, Harapat SR, Stanski DR: High-performance liquid Chromatographie method for determining thiopental concentrations in twelve rat tissues: Application to physiologic modeling of disposition of barbiturate. J Chromatogr 1989; 490:339-53
19. Stutzmann JM, Lucas M, Blanchard JC, Laduron PM: Riluzole, a glutamate antagonist, enhances slow wave and REM sleep in rats. Neurosci Lett 1988; 88:195-200
20. MacIver MB, Roth SH: Inhalation anaesthetics exhibit pathway-specific and differential actions on hippocampal synaptic responses in vitro. Br J Anaesth 1988; 60:680-91
21. A,slow feed forward inhibition in CA1 neuron dentrites (abstract). ANESTHESIOLOGY 1995; 83:A751
22. MacIver MB, Tauck DL, Kendig JJ: General anaesthetic modification of synaptic facilitation and long-term potentiation in hippocampus. Br J Anaesth 1989; 62:301-10
23. Mody I, Tanelian DL, MacIver MB. Halothane enhances tonic neuronal inhibition by elevating intracellular calcium. Brain Res 1991; 538:319-23
24. A-mediated neuronal inhibition. Ann N Y Acad Sci 1991; 625:91-6
25. MacIver MB, Roth SH: Barbiturate effects on hippocampal excitatory synaptic responses are selective and pathway specific. Can J Physiol Pharmacol 1987; 65:385-94
26. MacIver MB, Kendig JJ: Anesthetic effects on resting membrane potential are voltage-dependent and agent-specific. ANESTHESIOLOGY 1991; 74:83-8
27. A chloride currents underlie the thiopental induced slowing of EEC (abstract). ANESTHESIOLOGY 1994; 81:A798
28. Mikulec AA, Amagasu SM, Monroe FA, MacIver MB: Three sites of action are necessary and sufficient for halothane-induced depression of hippocampal CA 1 neurons (abstract). ANESTHESIOLOGY 1995; 83:A1266
29. Malgouris C, Bardot F, Daniel M, Pellis F, Rataud J, Uzan A, Blanchard JC, Laduron PM: Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils. J Neurosci 1989; 9:3720-7
30. Pratt J, Rataud J, Bardot F, Roux M, Blanchard JC, Laduron PM, Stutzmann JM: Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia. Neurosci Lett 1992; 140:225-30
31. Hubert JP, Delumeau JC, Glowinski J, Premont J, Doble A: Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: Evidence for a dual mechanism of action. Br J Pharmacol 1994; 113:261-7
32. Boireau A, Miquet JM, Dubedat P, Meunier M, Doble A: Riluzole and experimental parkinsonism: Partial antagonism of MPP(+)-induced increase in striatal extracellular dopamine in rats in vivo. Neuroreport 1994; 5:2157-60
33. Butterworth JT, Strichartz GR: Molecular mechanisms of local anesthesia: A review. ANESTHESIOLOGY 1990; 72:711-34
34. Guo XT, Castle NA, Chernoff DM, Strichartz GR: Comparative inhibition of voltage-gated cation channels by local anesthetics. Ann N Y Acad Sci 1991; 625:181-99
35. Benoit E, Escande D: Fast K channels are more sensitive to riluzole than slow K channels in myelinated nerve fibre. Pflugers Arch 1993; 422:536-8
36. Brown DL, Ransom DM, Hall JA, Leicht CH, Schroeder DR, Offord KP: Regional anesthesia and local anesthetic-induced systemic toxicity: Seizure frequency and accompanying cardiovascular changes. Anesth Analg 1995; 81:321-8