The apoB-100 gene EcoRI polymorphism influences the relationship between features of the insulin resistance syndrome and the hyper-apoB and dense LDL phenotype in men

Diabetes

Volumn 45, Issue 10, 1996, Pages 1405-1411

  Vohl, Marie Claude ^a   Tchernof, André ^a   Dionne, France T ^b   Moorjani, Sital ^a   Prud'homme, Denis ^b   Bouchard, Claude ^b   Nadeau, André ^a   Lupien, Paul J ^a   Després, Jean Pierre ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; CORONARY RISK; DYSLIPIDEMIA; GENE EXPRESSION; GENETIC POLYMORPHISM; HUMAN; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPOPROTEIN BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; OBESITY; PRIORITY JOURNAL;

EID: 0029780068     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.10.1405     Document Type: Article

References (72)

1. Kissebah AH, Krakower GR: Regional adiposity and morbidity. Physiol Rev 74:761-811, 1994
2. Björntorp P: Abdominal obesity and the development of non-insulin-dependent diabetes mellitus. Diab Metab Rev 4:615-622, 1988
3. Després JP, Moorjani S, Lupien PJ, Tremblay A, Nadeau A, Bouchard C: Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease. Arteriosclerosis 10:497-511, 1990
4. Kissebah AH, Peiris A: Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus. Diabetes Metab Rev 5:83-109, 1989
5. Ohlson LO, Larsson B, Svärdsudd K, Welin L, Eriksson H, Wilhemsen L, Björntorp P, Tibblin G: The influence of body fat distribution on the incidence of diabetes mellitus: 13.5 years of follow-up of the participants in the study of men born in 1913. Diabetes 34:1055-1058, 1985
6. Lapidus L, Bengtsson C, Larsson B, Pennert K, Rybo E, Sjöström L: Distribution of adipose tissue and risk of cardiovascular disease and death: a 12-year follow-up of participants in the population study of Gothenberg, Sweden. Br Med J 289:1261-1263, 1984
7. Larsson B, Svärdsudd K, Welin L, Wilhemsen L, Björntorp P, Tibblin G: Abdominal adipose tissue distribution, obesity and risk factor of cardio-vascular disease and death: 13 year follow-up of participants in the study of men born in 1913. Br Med J 288:1401-1404, 1984
8. Stokes J, Garrison RJ, Kannel WB: The independent contributions of various indices of obesity to the 22-year incidence of coronary heart disease: the Framingham Heart Study. In Metabolic Complications of Human Obesities. Vague J, Björntorp P, Guy-Grand B, Rebuffé-Scrive M, Vague P, Eds. Amsterdam, Elsevier, 1985, p. 49-57
9. Ducimetière P, Richard J, Cambien F: The pattern of subcutaneous fat distribution in middle-aged men and the risk of coronary heat disease: the Paris prospective study. Int J Obes 10:299-240, 1986
10. Donahue RP, Abbott RD, Bloom E, Reed DM, Yano K: Central obesity and coronary heart disease in men. Lancet 1:821-824, 1987
11. Terry RB, Page WF, Haskell WL: Waist/hip ratio, body mass index and premature cardiovascular disease mortality in US army veterans during a twenty-three year follow-up study. Int J Obes 16:417-423, 1992
12. Després JP, Lamarche B: Effects of diet and physical activity on adiposity and body fat distribution: implications for the prevention of cardio-vascular disease. Nutr Res Rev 6:137-159, 1993
13. Després JP: Visceral obesity: a component of the insulin-resistance-dyslipidemic syndrome. Can J Cardiol 10:17B-22B, 1994
14. Després JP, Moorjani S, Lupien PJ, Tremblay A, Nadeau A, Bouchard C: Genetic aspects of susceptibility to obesity and related dyslipidemias. Mol Cell Biochem 113:151-169, 1992
15. Pouliot MC, Després JP, Dionne FT, Vohl MC, Moorjani S, Prud'homme D, Bouchard C, Lupien PJ: ApoB-100 gene EcoRI polymorphism: relations to plasma lipoprotein changes associated with abdominal visceral obesity. Arterioscler Thromb 14:527-533, 1994
16. Bounder J, Kager L, Ostman J, Arner P: Differences at the receptor and postreceptor levels between human omental and subcutaneous adipose tissue in the action of insulin on lipolysis. Diabetes 32:117-123, 1983
17. Kissebah AH, Adams PW, Wynn V: Inter-relationships between insulin secretion and plasma free fatty acid and triglyceride transport kinetics in maturity onset diabetes and the effect of phenethylbiguanide (phenformin). Diabetologia 10:119-130, 1974
18. Howard BV: Lipoprotein metabolism in diabetes mellitus. J Lip Res 28:613-628, 1987
19. Després JP: Lipoprotein metabolism in visceral obesity. Int J Obes 15:45-52, 1991
20. Frayn KN, Coppack SW: Insulin resistance, adipose tissue and coronary heart disease. Clin Sci 82:1-8, 1992
21. Jensen MD, Haymond MW, Rizza RA, Cryer PE, Miles JM: Influence of body fat distribution on free fatty acid metabolism in obesity. J Clin Invest 83:1168-1173, 1989
22. Pouliot MC, Després JP, Nadeau A, Tremblay A, Moorjani S, Lupien PJ, Thériault G, Bouchard C: Associations between regional body fat distribution, fasting plasma fatty acid level and glucose tolerance in premenopausal women. Int J Obes 14:293-302, 1990
23. Mauriège P, Després JP, Moorjani S, Prud'homme D, Lamarche B, Bouchard C, Nadeau A, Tremblay A, Lupien PJ: Abdominal and femoral adipose tissue lipolysis and cardiovascular disease risk factors in men. Eur J Clin Invest 23:729-740, 1993
24. Pullinger CR, North JD, Teng B, Riflci VA, Ronhild de Brito AE, Scott J: The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin and insulin and measurement of the mRNA half-life. J Lip Res 30:1065-1077, 1989
25. Moberly JA, Cole TG, Alpers DH, Schonfeld G: Oleic acid stimulation of apolipoprotein B secretion from HepG2 cells and Caco-2 cells occurs posttranscriptionally. Biochim Biophys Acta 1042:70-80, 1990
26. Cianflone KM, Yasruel Z, Rodriguez MA, Vas D, Sniderman AD: Regulation of apoB secretion from HepG2 cells: evidence for a critical role for cholesterol ester synthesis in the response to a fatty acid challenge. J Lip Res 31:2045-2055, 1990
27. Dixon JL, Furukawa S, Ginsberg HN: Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from HepG2 cells by inhibiting early intracellular degradation of apolipoprotein B. J Biol Chem 256:5080-5086, 1991
28. Young S: Recent progress in understanding apolipoprotein B. Circulation 80:219-233, 1989
29. Paulweber B, Friedl W, Krempler F, Humphries SE, Sandhofer F: Association of DNA polymorphism at the apolipoprotein B gene locus with coronary heart disease and serum very low density lipoprotein levels. Arteriosclerosis 10:17-24, 1990
30. Rajput-Williams J, Knott TJ, Wallis SC, Sweetnam P, Yarnell J, Cox N, Bell GI, Miller NE, Scott J: Variation of apolipoprotein-B gene is associated with obesity, high blood cholesterol levels, and increased risk of coronary heart disease. Lancet 31:1442-1446, 1988
31. Genest JJ Jr, Ordovas JM, McNamara JR, Robbins AM, Meade T, Cohn SD, Salem DN, Wilson PWF, Masharani U, Frossard PM, Schaefer EJ: DNA polymorphisms of the apolipoprotein B gene in patients with premature coronary heart disease. Atherosclerosis 82:7-17, 1990
32. Myant NB, Gallagher J, Barbir M, Thompson GR, Wile D, Humphries SE: Restriction fragment length polymorphisms in the apoB gene in relation to coronary artery disease. Atherosclerosis 77:193-201, 1989
33. Hegele RA, Huang LS, Herbert PN, Blum CB, Buring JE, Hennekens CH, Breslow JL: Apolipoprotein B-gene DNA polymorphisms associated with myocardial infarction. N Engl J Med 315:1509-1515, 1986
34. Monsalve MV, Robinson D, Woolcock NE, Powell JT, Greenhalgh RM, Humphries SE: Within-individual variation in serum cholesterol levels: association with DNA polymorphisms at the apolipoprotein B and AI-CIII-AIV loci in patients with peripheral arterial disease. Clin Genet 39:260-273, 1991
35. Ukkola O, Savolainen MJ, Salmela PI, von Dickhoff K, Kesäniemi YA: Apolipoprotein B gene DNA polymorphisms are associated with macroand microangiopathy in non-insulin-dependent-diabetes mellitus. Clin Genet 44:177-184, 1993
36. Crouse JR, Parks JS, Schey HM, Kahl RF: Studies of low density lipoprotein molecular weight in human beings with coronary artery disease. J Lip Res 26:566-574, 1985
37. Fisher WR: Heterogeneity of plasma low density lipoprotein: manifestations of the physiologic phenomenon in man. Metabolism 32:283-291, 1983
38. Austin MA, Breslow JL, Hennekens CH, Buring JE, Willett WC, Krauss RM: Low density lipoprotein subclass patterns and risk of myocardial infarction. JAMA 260:1917-1921, 1988
39. Campos H, Genest JJ Jr, Blijlevens E, McNamara JR, Jenner JL, Ordovas JM, Wilson PWF, Schaefer EJ: Low density lipoprotein particle size and coronary heart disease. Arterioscler Thromb 12:187-195, 1992
40. Boerwinkle E, Lee SS, Butler R, Schumaker VN, Chan L: Rapid typing of apolipoprotein B DNA polymorphisms by DNA amplification: associations between Ag epitopes of human apolipoprotein B-100, a signal peptide insertion/deletion polymorphism, and a 3′ flanking DNA variable number of tandem repeats polymorphism of the apolipoprotein B gene. Atherosclerosis 81:225-232, 1990
41. Behnke AR, Wilmore JH: Evaluation and Regulation of Body Build and Composition. Englewood Cliffs, NJ, Prentice-Hall, 1974, p. 20-37
42. Siri WE: The gross composition of the body. Adv Biol Med Phys 4:239-280, 1956
43. Meneely GR, Kaltreider NL: Volume of the lung determined by helium dilution. J Clin Invest 28:129-139, 1949
44. Standardization of anthropometric measurements. In The Airlie (VA) Consensus Conference. Lohman T, Roche A, Martorel R, Eds. Champaign, IL, Human Kinetics Publishers, 1988, p. 39-80
45. Ferland M, Després JP, Tremblay A, Pinault S, Nadeau A, Moorjani S, Lupien PJ, Thériault G, Bouchard C: Assessment of adipose tissue distribution by computed axial tomography in obese women: association with body density and anthropometric measurements. Br J Nutr 61:139-148, 1989
46. 40K, and tritium. Am J Physiol 250:E736-E745, 1986
47. Kvist H, Tylen U, Sjöstr̈m L: Adipose tissue volume determination in women by computed tomography: technical considerations. Int J Obes 10:53-67, 1986
48. Richterich R, Dauwalder H: Zur bestimmung der plasmaglukosekonzentration mit der hexokinase-glucose-6-phosphat-dehydrogenase-method. Schweiz Med Wockenschr 101:615-618, 1971
49. Desbuquois B, Aurbach GD: Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays. J Clin Endocrinol Metab 37:732-738, 1971
50. Noma A, Okabe H, Kita M: A new colorimetric microdetermination of free fatty acids in serum. Clin Chim Acta 43:317-320, 1973
51. Havel RJ, Eder HA, Bragdon JH: The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34:1345-1354, 1955
52. Burstein M, Samaille J: Sur un dosage rapide du cholestérol lié aux alpha et aux bêta lipoprotéines du sérum. Clin Chem Acta 5:609-610, 1960
53. Laurell CB: Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal Biochem 15:45-52, 1966
54. Moorjani S, Dupont A, Labrie F, Lupien PJ, Brun D, Gagné C, Giguère M, Bélanger A: Increase in plasma high-density lipoprotein concentration following complete androgen blockage in men with prostatic carcinoma. Metabolism 36:244-250, 1987
55. Krauss RM, Burke DJ: Identification of multiple subclasses of plasma low density lipoproteins in normal humans. J Lip Res 23:97-104, 1982
56. McNamara J, Campos H, Ordovas JM, Peterson J, Wilson PWF, Schaefer EJ: The effect of gender, age, and lipid status on low density lipoprotein subfraction distribution: results of the Framingham offspring study. Arteriosclerosis 7:483-490, 1987
57. Tehernof A, Lamarche B, Prud'homme D, Nadeau A, Moorjani S, Labrie F, Lupien PJ, Després JP: The dense LDL phenotype: association with plasma lipoprotein levels, visceral obesity and hyperinsulinemia in men. Diabetes Care 19:629-637, 1996
58. Després JP: Obesity and lipid metabolism: relevance of body fat distribution. Curr Opin Lipidol 2:5-15, 1991
59. Cabezas MC, de Bruin TWA, de Valk HW, Shoulders CC, Jensen H, Erkelens DW: Impaired fatty acid metabolism in familial combined hyperlipidemia: a mechanism associating hepatic apolipoprotein B overproduction and insulin resistance. J Clin Invest 92:160-168, 1993
60. Sniderman AD, Cianflone K: Substrate delivery as a determinant of hepatic apoB secretion. Arterioscler Thromb 13:629-636, 1993
61. Dashti N, Wolfbauer G: Secretion of lipids, apoproteins, and lipoproteins by human hepatoma cell line HepG2: effects of oleic acid and insulin. J Lip Res 26:4837-4846, 1987
62. Sparks J, Sparks CE: Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes. J Biol Chem 265:8854-8862, 1990
63. Jackson TK, Salhanick AI, Elovson J, Deichman ML, Amatruda JM: Insulin regulates apolipoprotein B turnover and phosphorylation in rat hepatocytes. J Clin Invest 86:1746-1751, 1990
64. Salhanick AI, Schwartz SI, Amatruda M: Insulin inhibits apolipoprotein B secretion in isolated human hepatocytes. Metab Clin Exp 40:275-279, 1991
65. Lewis GF, Uffelman KD, Szeto LW, Steiner G: Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB production in normal weight and obese individuals. Diabetes 42:833-842, 1993
66. Després JP, Marette A: Relation of components of insulin resistance syndrome to coronary disease risk. Curr Opin Lipidol 5:274-289, 1994
67. Houlston RS, Turner PR, Lewis B, Humphries SE: Genetic epidemiology of differences in low-density lipoprotein (LDL) cholesterol concentration: possible involvement of variation at the apolipoprotein B gene locus in LDL kinetics. Genet Epidemiol 7:199-210, 1990
68. Gallagher JJ, Myant NB: Does the EcoRI polymorphism in the human apolipoprotein B gene affect the binding of low-density lipoprotein to the low-density lipoprotein receptor? Arterioscler Thromb 12:256-160, 1992
69. Austin MA, Horowitz H, Wysman E, Krauss RM, Brunzell J: Bimodality of plasma apolipoprotein B levels in familial combined hyperlipidemia. Atherosclerosis 92:67-77, 1992
70. Sniderman A, Brown BG, Stewart AF, Cianflone C: From familial combined hyperlipidemia to hyperapoB: unravelling the overproduction of hepatic apolipoprotein B. Curr Opin Lipidol 3:137-142, 1992
71. Austin MA, King MC, Vranizan KM, Krauss RM: Atherogenic lipoprotein phenotype: a proposed genetic marker for coronary heart disease risk. Circulation 82:495-506, 1990
72. Reaven GM, Chen YDI, Jeppesen J, Maheux P, Krauss RM: Insulin resistance and hyperinsulinemia in individuals with small, dense, low density lipoprotein particles. J Clin Invest 92:141-146, 1993