Virulence regulon polymorphism in group A streptococci revealed by long PCR and implications for epidemiological and evolutionary studies

Journal of Medical Microbiology

Volumn 45, Issue 4, 1996, Pages 285-293

  Hookey, J V ^a   Saunders, N A ^a   Clewley, J P ^a   Efstratiou, Androulla ^b   George, R C ^b  

^a Virus Reference Division   (United Kingdom)

^b CENTRAL PUBLIC HEALTH LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; GENETIC POLYMORPHISM; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REGULON; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEROTYPE; STREPTOCOCCUS GROUP A; STREPTOCOCCUS PYOGENES;

EID: 0029780049     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/00222615-45-4-285     Document Type: Article

References (38)

1. Eisenberg MJ. Rheumatic heart disease in the developing world: prevalence, prevention, and control. Eur Heart J 1993; 14: 122-128.
2. Bisno AL. Group A streptococcal infections: the changing scene. Curr Opin Infect Dis 1995; 8: 117-122.
3. Stevens DL, Tanner MH, Winship J et al. Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A. N Engl J Med 1989; 321: 1-7.
4. Spencer RC. Review: invasive streptococci. Eur J Clin Microbiol Infect Dis 1995; 14 Suppl 1: S26-S32.
5. Anon. Invasive group A streptococcal infections in Gloucestershire. Commun Dis Rep CDR Wkly 1994; 4: 97.
6. Anon. Invasive group A streptococcal infections: first report of enhanced surveillance. Commun Dis Rep CDR Wkly 1995; 5: 10.
7. Anon. Invasive group A streptococcal infections: second report of the enhanced surveillance scheme. Commun Dis Rep CDR Wkly 1995; 5: 123-124.
8. Roggiani M, Schlievert PM. Streptococcal toxic shock syndrome, including necrotizing fasciitis and myositis. Curr Opin Infect Dis 1994; 7: 423-426.
9. Nowak R. Flesh-eating bacteria: not new, but still worrisome. Science 1994; 264: 1665.
10. Lancefield RC. A serological differentiation of human and other groups of hemolytic streptococci. J Exp Med 1933; 57: 571-595.
11. Rotta J, Krause RM, Lancefield RC, Everly W, Lackland H. New approaches for the laboratory recognition of M types of group A streptococci. J Exp Med 1971; 134: 1298-1315.
12. Gooder H. Association of a serum opacity reaction with serological type in Streptococcus pyogenes. J Gen Microbiol 1961; 25: 347-352.
13. Top FH, Wannamaker LW. The serum opacity reaction of Streptococcus pyogenes: frequency of production of streptococcal lipoproteinase by strains of different serological types and the relationship to M protein production. J Hyg 1968; 66: 49-58.
14. Top FH, Wannamaker LW. The serum opacity reaction of Streptococcus pyogenes. The demonstration of multiple, strain-specific lipoproteinase antigens. J Exp Med 1968; 127: 1013-1034.
15. Widdowson JP, Maxted WR, Grant DL. The production of opacity in serum by group A streptococci and its relationship with the presence of M antigen. J Gen Microbiol 1970; 61: 343-353.
16. Skjold SA, Wannamaker LW. Method for phage typing group A type 49 streptococci. J Clin Microbiol 1976; 4: 232-238.
17. Tagg JR, Bannister LV. "Fingerprinting" beta-haemolytic streptococci by their production of and sensitivity to bacteriocine-like inhibitors. J Med Microbiol 1979; 12: 397-411.
18. Musser JM, Hauser AR, Kim MH, Schlievert PM, Nelson K, Selander RK. Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases: clonal diversity and pyrogenic exotoxin expression. Proc Natl Acad Sci USA 1991; 88: 2668-2672.
19. Musser JM, Gray BM, Schlievert PM, Pichichero ME. Streptococcus pyogenes pharyngitis: characterization of strains by multilocus enzyme genotype, M and T protein serotype, and pyrogenic exotoxin gene probing. J Clin Microbiol 1992; 30: 600-603.
20. Mylvaganam H, Bjorvatn B, Hofstad T, Hjetland R, Arne Hoiby E, Holm SE. Small-fragment restriction endonuclease analysis in epidemiological mapping of group A streptococci. J Med Microbiol 1994; 40: 256-260.
21. Martin DR, Single LA. Molecular epidemiology of group A Streptococcus M type 1 infections. J Infect Dis 1993; 167: 1112-1117.
22. Stanley J, Linton D, Desai M, Efstratiou A, George R. Molecular subtyping of prevalent M serotypes of Streptococcus pyogenes causing invasive disease. J Clin Microbiol 1995; 33: 2850-2855.
23. Bruneau S, de Montclos H, Drouet E, Denoyel GA. rRNA gene restriction patterns of Streptococcus pyogenes: epidemiological applications and relation to serotypes. J Clin Microbiol 1994; 32: 2953-2958.
24. Whatmore AM, Kehoe MA. Horizontal gene transfer in the evolution of group A streptococcal emm-like genes: gene mosaics and variation in Vir regulons. Mol Microbiol 1994; 11: 363-374.
25. Podbielski A, Krebs B, Kaufhold A. Genetic variability of the emm-related gene of the large vir regulon of group A streptococci: potential intra- and intergenomic recombination events. Mol Gen Genet 1994; 243: 691-698.
26. Chen CC, Bormann N, Cleary PP. VirR and Mry are homologous trans-acting regulators of M protein and C5a peptidase expression in group A streptococci. Mol Gen Genet 1993; 241: 685-693.
27. Chen CC, Cleary PP. Complete nucleotide sequence of the streptococcal C5a peptidase gene from Streptococcus pyogenes. J Biol Chem 1990; 265: 3161-3167.
28. Whatmore AM, Kapur V, Musser JM, Kehoe MA. Molecular population genetic analysis of the enn subdivision of group A streptococcal emm-like genes: horizontal gene transfer and restricted variation among enn genes. Mol Microbiol 1995; 15: 1039-1048.
29. Barnes WM. PCR amplification of up to 35-kb DNA with high fidelity and high yield from λ bacteriophage templates. Proc Natl Acad Sci USA 1994; 91: 2216-2220.
30. Pitcher DG, Saunders NA, Owen RJ. Rapid extraction of bacterial genomic DNA with guanidium thiocyanate. Lett Appl Microbiol 1989; 8: 151-156.
31. Cleary P, Retnoningrum D. Group A streptococcal immunoglobulin-binding proteins: adhesins, molecular mimicry or sensory proteins? Trends Microbiol 1994; 2: 131-136.
32. Perez-Casal J, Caparon MG, Scott JR. Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systems. J Bacteriol 1991; 173: 2617-2624.
33. Perez-Casal JF, Dillon HF, Husmann LK, Graham B, Scott JR. Virulence of two Streptococcus pyogenes strains (types M1 and M3) associated with toxic-shock-like syndrome depends on an intact myr-like gene. Infect Immun 1993; 61: 5426-5430.
34. McLandsborough LA, Cleary PP. Insertional inactivation of virR in Streptococcus pyogenes M49 demonstrates that VirR functions as a positive regulator of ScpA, FcRA, OF, and M protein. FEMS Microbiol Lett 1995; 128: 45-52.
35. Gardiner D, Hartas J, Currie B, Mathews JD, Kemp DJ, Sriprakash KS. Vir typing: a long-PCR method for Group A streptococci. PCR Methods Appl 1995; 4: 288-293.
36. Schwartz B, Facklam RR, Breiman RF. Changing epidemiology of group A streptococci infection in the USA. Lancet 1990; 336: 1167-1171.
37. Cleary PP, Kaplan EL, Handley JP et al. Clonal basis for resurgence of serious Streptococcus pyogenes disease in the 1980s. Lancet 1992; 339: 518-521.
38. Upton M, Carter PE, Morgan M, Edwards GF, Pennington TH. Clonal structure of invasive Streptococcus pyogenes in Northern Scotland. Epidemiol Infect 1995; 115: 231-241.