Hematopoietic growth factors in leukemia

Pathology Research and Practice

Volumn 192, Issue 7, 1996, Pages 734-742

  Touw, I P ^a   Dong, F ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Autocrine stimulation; Growth factor receptors; Hematopoietic growth factors; Leukemia

Indexed keywords

GROWTH FACTOR RECEPTOR; HEMOPOIETIC GROWTH FACTOR;

AUTOCRINE EFFECT; CELL MATURATION; CELL PROLIFERATION; CYTOGENETICS; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; PATHOPHYSIOLOGY; REVIEW;

EID: 0029779615     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0344-0338(96)80095-1     Document Type: Article

References (81)

1. Adkins B, Leutz A, Graf T (1984) Autocrine growth induced by src-related protooncogenes in transformed chicken myeloid cells. Cell 39: 439-445
2. Bartley TD, Bogenberger J, Hunt P, Li YS, Lu HS, Martin F, Chang MS, Samal B, Nichol JL, Swift S, Johnson MJ, Hsu RY, Parker VP, Suggs S, Skrine JD, Merewether LA, Clogston C, Hsu E, Hokom MM, Hornkohi A, Choi E, Pangelinan M, Sun Y, Mar V, McNinch J, Simonet L, Jacobsen F, Xie C, Shutter J, Chute H, Basu R, Selander L, Trollinger D, Sieu L, Padilla D, Trail G, Elliott G, Izumi R, Covey T, Crouse J, Garcia A, Xu W, Castillo JD, Biron J, Cole S, Hu MCT, Pacifici R, Ponting I, Saris C, Wen D, Yung YP, Lin H, Bosselman RA (1994) Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl Cell 77: 1117-1124
3. Bazan JF (1990) Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 87: 6934-6938
4. Bradbury D, Rogers S, Kozlowski R, Bowen G, Reilly IAG, Russell NH (1990) Interleukin-1 is one factor which regulates the autocrine production of GM-CSF by the blasts of acute myeloblastic leukemia. Br J Haematol 76: 488-493
5. Budel LM, Delwel R, van Buitenen C, Hoogerbrugge H, Löwenberg B (1993) Effects of Kit Ligand on acute myeloid leukeima cells in vitro: Effects of combinations with other cytokines. Leukemia 7: 426-434
6. Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R, Soltoff S (1991) Oncogenes and signal transduction. Cell 64: 281-302
7. Castaigne S, Chomienne C, Daniel MT, Ballerini P, Berger R, Fenaux P, Degos L (1990) All trans-retinoic acid as a differentition therapy for acute promyelocytic leukemia: I. Clinical results. Blood 76: 1704-1709
8. Clark SC, Kamen R (1987) The human colony stimulating factors. Science 236: 1229-1237
9. Cosman D (1993) The hematopoietin receptor superfamily. Cytokine 5: 95-106
10. D'Andrea R, Rayner J, Moretti P, Lopez A, Goodall GJ, Gonda TJ, Vadas M (1994) A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte macrophage colony-stimulating factor, and IL-5 that leads too ligand independence and tumorigenicity. Blood 83: 2802-2808
11. Daenen S, Vellenga E, Van Dobbenburgh OA, Halie MR (1986) Retinoic acid as antileukemic therapy in a patient with acute promyelocytic leukemia and aspergillus pneumonia. Blood 67: 559-561
12. Dale DC, Davis M, Vincent ME (1994) Use of filgrastim (r-metHuG-CSF) in severe chronic neutropenia. In: Morstyn G, Dexter TM (Eds) Filgrastin in clinical practice, pp 83-101. Marcel Dekker Inc, New York
13. Davis I, Morstyn G (1992) Clinical uses of growth factors. In: Lord B. I., Dexter T. M. (Eds) Balliere's Clinical Hematology, Vol. 5, no 3, Growth Factors in Haemopoiesis, pp. 753-786. Balliere Tindal, London, Philadelphia, Sidney, Tokyo, Toronto
14. De Thé H, Lavau C, Marchio A, de Chomienne C, Degos L, Dejean A (1991) The PML-RARα fusion mRNA generated by the t(15;17) translocation in human acute promyelocytic leukemia encodes a functionally altered RAR. Cell 66: 675-684
15. De la Chapelle A, Träskelin AL, Juvonen E (1993) Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci USA 90: 4495-4499
16. Delwel R, Van Buitenen C, Salem M, Bot F, Gillis S, Kaushansky K, Altrock B, Löwenberg B (1989) Interleukin-1 stimulates proliferation of acute myeloid leukemia cells by induction of granulocyte-macrophage colony-stimulating factor release. Blood 74: 586-593
17. Delwel R, Schipper P, Van Buitenen C, Van Agthoven T, Touw I, Löwenberg B (1990) Comparative analysis of IL-1 regulated and spontaneous growth of acute myeloid leukemia in vitro. Bone Marrow Transplant 6 (suppl 1): 22-26
18. Delwel HR, Salem M, Dorssers L, Wagemaker G, Clark SC, Löwenberg B (1988) Growth regulation of human acute myeloid leukeima: Effects of five recombinant hematopoietic factors in a serum-free culture system. Blood 72: 1944-1949
19. Dong F, Van Paassen M, Van Buitenen C, Hoefsloot LH, Löwenberg B, Touw IP (1995) A point mutation in the granulocyte colony-stimulating factor receptor (G-CSF-R) gene in a case of acute myeloid leukemia results in the overexpression of a novel G-CSF-R isoform. Blood 85: 902-911
20. Dong F, Van Buitenen C, Pouwels K, Hoefsloot LH, Löwenberg B, Touw IP (1993) Distinct cytoplasmic regions of the granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation. Mol Cell Biol 13: 7774-7781
21. Dong F, Brynes RK, Tidow N, Weite K, Löwenberg B, Touw IP (1995a) Mutations truncating the C-terminal maturation region of the G-CSF receptor in acute myeloid leukemia preceded by severe congenital neutropenia. N Engl J Med 333: 487-493
22. Dong F, Hoefsloot LH, Schelen AM, Breeders LCAM, Meijer Y, Veerman AJP, Touw IP, Löwenberg B (1994) Identification of a nonsense mutation in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia. Proc Natl Acad Sci USA 91: 4480-4484
23. Elbaz O, Budel LM, Hoogerbrugge H, Touw IP, Delwel R, Mahmoud LA, Löwenberg B (1991) Tumor necrosis factor regulates the expression of GM-CSF and IL-3 receptors on human acute myeloid leukemia cells. Blood 77: 989-995
24. Elbaz O, Budel LM, Hoogerbrugge H, Touw IP, Delwel R, Mahmoud LA, Löwenberg B (1991) Tumor necrosis factor downregulates G-CSF receptor expression on human AML cells and granulocytes. J Clin Invest 87: 838-841
25. Ema E, Kitano K, Suda T, Muroi K, Ohta M, Yoshida M, Sakamoto S, Eguchi M, Miura Y (1990) In vitro differentiation of leukemic cells to eosinophils in the presence of interleukin-5 in two cases of acute myeloid leukemia with the translocation (8;21)(q22;q22). Blood 75: 350-356
26. Erickson P, Gao J, Chang K-S, Look T, Whisenant E, Raimondi S, Lasher R, Trujillo J, Rowley J, Drabkin H (1992) Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt. Blood 80: 1825-1831
27. Estey E, Thall PF, Kantarjian H, O'Brien S, Koller CA, Beran M, Gutterman J, Deisseroth A, Keating A (1992) Treatment of newly diagnosed acute myelogenous leukemia with granulocyte-macrophage colony stimulating factor (GM-CSF) before and during continuous infusion of high-dose Ara-C and Daunorubricin: Comparison to patients treated without GM-CSF. Blood 79: 2246-2255
28. Fluckiger AC, Rossi JF, Bussel A, Bryon P, Banchereau J, Defrance T (1992) Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B cell tropic factors. Blood 80: 3173-3181
29. French-American-British Cooperative Group (1985) Proposed revised criteria for the classification of acute myeloid leukemia. Ann Intern Med 103: 620-625
30. Fukunaga R, Ishizaka-Ikeda E, Pan C-X, Seto Y, Nagata S (1991) Functional domains of the granulocyte colony-stimulating factor receptor. EMBO J 10: 2855-2865
31. Fukunaga R, Ishizaka-Ikeda E, Nagata S (1993) Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor. Cell 74: 1079-1087
32. Gillio AP, Gabrilove JL (1993) Cytokine treatment of inherited bone marrow failure syndromes. Blood 81: 1669-1674
33. Graf T, Weizsaecker FV, Grieser S, Coll J, Stehelin D, Patschinsky T, Bister K, Bechade C, Calothy G, Leutz A (1986) V-mil induces autocrine growth and enhanced tumorigenecity in m-myc transformed avian macrophages. Cell 45: 357-364
34. Greer P, Maltby V, Rossant J, Bernstein A, Pawson T (1990) Myeloid expression of the human c-fps/fes proto-oncogene in transgenic mice. Mol Cell Biol 10: 2521-2527
35. Griffin JD, Lowenberg B (1986) clonogenic cells in acute myelobiastic leukemia. Blood 68: 1185-1195
36. Grimaldi JC, Meeker TC (1989) The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene. Blood 73: 2081-2085
37. Hunter AE, Rogers SY, Roberts IA, Barrett AJ, Russel N (1993) Autonomous growth of blast cells is associated with reduced survival in acute myeloblastic leukemia. Blood 82: 899-903
38. Hunter T (1991) Cooperation between oncogenes. Cell 64: 249-270
39. Jansen JH, Mahfoudi A, Rambaud S, Lavau C, Wahli W, Dejean A (1995) Multimeric complexes of the PML-retinoic acid receptor α fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways. Proc Natl Acad Sci USA 92: 7401-7405
40. Kaushansky K, Lok S, Holly RD, Broudy VC, Lin N, Baily MC, Frostrom JW, Buddle MM, Oort PJ, Hagen FS, Roth GJ, Papayannopoulou T, Foster DC (1994) Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 369: 568-571
41. Kawano M, Hirano T, Matsuda T, Taga T, Horii Y, Iwato K, Asaoku H, Tang B, Tanabe O, Tanaka H, Kuramoto A, Kishimoto T (1988) Autocrine generation and essential requirement of BSF-2/IL-6 for human multiple myelomas. Nature 332: 83-85
42. Kazizuka A, Miller WH, Umesono K, Warrell RP, Frankel SR, Murty VVVS, Dmitrovsky E, Evans RM (1991) Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML. Cell 66: 663-674
43. Keller JR, Jacobsen SEW, Dubois C, Hestdal K, Ruscetti FW (1992) Transforming growth factor-β: A bidirectional regulator of hematopoietic cell growth. Int J Cell Cloning 10; 2-11
44. Kluin-Nelemans HC, Beverstock GC, Mollevanger P, Wessels HW, Hoogendoorn E, Willemze R, Falkenburg JHF (1994) Proliferation and cytogenetic analysis of hairy cell leukemia upon stimulation via the CD40 antigen. Blood 84: 3134-3141
45. Kostmann R (1956) Infantile genetic agranulocytosis. Acta Paediatr Scand 45 (suppl 105): 1-78
46. Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Careres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE (1994) A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367: 645-648
47. Larsen A, Davis T, Curtis BM, Gimpel S, Sims JE, Cosman D, Park L, Sorensen E, March CJ, Smith CA (1990) Expression cloning of a human granulocyte colony stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains. J Exp Med 172: 1559-1570
48. Liu P, Tarlé SA, Hajra A, Claxton DF, Marlton P, Freedman M, Siciliano MJ, Collins FS (1993) Fusion between transcription factor CBFβ/PEBP2β and myosin heavy chain in acute myeloid leukemia. Science 261: 1041-1044
49. Lok S, Kaushansky K, Holly RD, Kuijper JL, Lofton Day CE, Oort PJ, Grant FJ, Heipel MD, Burkhead SK, Kramer JM, Bell LA, Sprecher CA, Blumberg H, Johnson R, Prunkard D, Ching AFT, Mathewes SL, Bailey MC, Forstrom JW, Buddle MM, Osborn SG, Evans SJ, Sheppard PO, Presnell SR, O'Hara PJ, Hagen FS, Roth GJ Foster DC (1994) Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369: 565-568
50. Longmore GD, Lodish HF (1991) An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene. Cell 67: 1089-1102
51. Lord KA, Abdollahi A, Hoffman-Liebermann B, Liebermann DA (1993) Protooncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation. Mol Cell Biol 13: 841-851
52. Löwenberg B, Van Putten WLJ, Touw IP, Delwel R, Santini V (1993) Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia. N Engl J Med 328: 614-619
53. Matsumara I, Kanakura Y, Kato T, Ikeda H, Ishikawa J, Horikawa Y, Hashimoto K, Moriyama Y, Tsujimura T, Nishiura T, Miyazaki H, Matsuzawa Y (1995) Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin. Blood 86: 703-709
54. Meeker TC, Hardy D, Willman C, Hogan T, Abrams J (1990) Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia. Blood 76: 285-289
55. Meng-er H, Yu-chen Y, Shu-rong C, Jin-ren C, Jia Chang L, Lin Z, Long-jun G, Zhen Y (1988) Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72: 567-572
56. Metcalf D (1989) The molecular control of cell division, differentiation, commitment and maturation in haematopoietic cells. Nature 339: 27-30
57. Metz T, Graf T, Leutz A (1991) Activation of cMGF expression is a critical step in avian myeloid leukemogenesis. EMBO J 10: 837-844
58. Meyers S, Lenny N, Hiebert SW (1995) The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation. Mol Cell Biol 15: 1974-1982
59. Miyajima A, Mui ALF, Ogorochi T, Sakamaki K (1993) Receptors for granulocyte macrophage colony-stimulating factor, interleukin-3, and interleukin-5. Blood 82: 1960-1974
60. Miyauchi J, Kelleher CA, Yang Y, Wong GG, Clark SC, Minden MD, Minkin S, McCulloch EA (1987) The effects of three recombinant growth factors, IL-3, GM-CSF, and G-CSF, on the blast cells of acute myeloblastic leukemia maintained in short term suspension culture. Blood 70: 657-663
61. Miyoshi H, Shimizu K, Kozu T, Maseki N, Kaneko Y, Ohki M (1991) t(8;21) Breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Proc Natl Acad Sci USA 88: 10431-10434
62. Moberts R, Hoogerbrugge H, Van Agthoven Th, Löwenberg B, Touw I (1989) Proliferative response of highly purified B chronic lymphocytic leukemia cells in serum free culture to interleukin-2 and tumor necrosis factors alpha and beta. Leuk Res 13: 973-980
63. Morishita K, Parganas E, Matsugi T, Ihle JN (1992) Expression of the Evi-1 zinc finger gene in 32Dcl3 myeloid cells blocks granulocytic differentiation in response locyte colony-stimulating factor. Mol Cell Biol 12: 183-189
64. Morishita K, Parganas E, Willman CL, Whittaker MH, Drabkin H, Oval J Taetle R, Ihle JN (1992) Activation of Evi-1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26. Proc Natl Acad Sci USA 89: 3937-3941
65. Murohashi I, Tonda S, Suzuki T, Nazata K, Yamashita Y, Nara N (1989) autocrine growth mechanisms of the progenitors of blast cells in acute myeloblastic leukemia. Blood 74: 35-41
66. Noguchi M, Yi H, Rosenblatt HM, Filipovich AH, Adelstein S, Modi WS, McBride OW, Leonard WJ (1993) Interleukin-2 receptor t chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73: 147-157
67. Nuchprayoon I, Meyers S, Scott LM, Suzow J, Hiebert S, Friedman AD (1994) PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBPZβ/CBFβb proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Mol Cell Biol 14: 5558-5568
68. Oster W, Cicco NA, Klein H, Hirano T, Kishimoto T, Lindemann A, Mertelsmann RH, Herrmann F (1989) Participation of the cytokines interleukin 6, tumor necrosis factor alpha, and interleukin-1 beta secreted by acute myelogenous leukemia blasts in autocrine and paracrine growth control. J Clin Invest 84: 451-457
69. Pebusque MJ, Lafage M, Lopez M, Mannoni P (1988) Preferential response of acute myeloid leukemias with translocations involving chromosome 17 to human recombinant granulocyte colony-stimulating factor. Blood 72: 257-265
70. Perez A, Kastner Ph, Sethi S, Lutz Y, Reibel C, Chambon P (1993) PMLR-AR homodimers: distinct DNA binding properties and heteromeric interactions with RXR. EMBO J 12: 3171-3182
71. Reilly IA, Kozlowski R, Russell NH (1989) Heterogeneous mechanisms of autocrine growth of AML blasts. Br J Haematol 72: 363-369
72. Salem M, Delwel R, Touw I, Mahmoud LA, Löwenberg B (1990) Modulation of colony stimulating factor (CSF) dependent growth of acute myeloid leukemia by tumor necrosis factor. Leukemia 4: 37-43
73. Sawyers CL, Denny CT, Witte ON (1991) Leukemia and the disruption of normal hematopoiesis. Cell 64: 337-350
74. Souyri M, Vigon I, Penciolelli J-F, Heard J-M, Tambourin P, Wendling F (1990) A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell 63: 1137-1147
75. 7:1 Tanaka T, Tanaka K, Ogawa S, Kurokawa M, Mitani K, Nishida Y, Shibata Y, Yazaki Y, Hirai H (1995) An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms. EMBO J 14: 341-350
76. Touw I, Pouwels K, Van Agthoven T, Van Gurp R, Budel L, Hoogerbrugge H, Delwel R, Goodwin R, Namen A, Löwenberg B (1990) Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia. Blood 75: 2097-2101
77. Touw I, Donath J, Pouwels K, Van Buitenen C, Schipper P, Santini V, Hagemeijer A, Löwenberg B, Delwel R (1991) Acute myeloid leukemias with chromosomal abnormalities involving the 21q22 region identified by their in vitro responsiveness to interleukin-5. Leukemia 5: 687-692
78. Wang S, Wang Q, Crute BE, Melnikova, IN, Keller SA, Speck NA (1993) Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor. Mol Cell Biol 13: 3324-3339
79. Warrell RP, Frankel SR, Miller WH, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M, Tarufi A, Jakubowski A, Gabrilove J, Gordon MS, Dmitrovsky E (1991) Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans retinoic acid). N Engl J Med 324: 1385-1393
80. Wörmann B, Gesner TG, Mufson RA, LeBien TW (1989) Proliferative effect of interleukin-3 on normal and leukemic human B cell precursors. Leukemia 3: 399-404
81. Young DC, Griffin JD (1986) Autocrine secretion of GM-CSF in acute myeloblastic leukemia. Blood 68: 1178-1181