Macrophage activation factors in the brains of aids patients

Journal of Neuro-AIDS

Volumn 1, Issue 2, 1996, Pages 1-16

  Achim, Cristian L ^a   Masliah, Eliezer ^b   Heyes, Melvyn P ^c   Sarnacki, Pamela ^a   Hilty, Cheryl ^a   Baldwin, Maria ^a   Wiley, Clayton A ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Encephalitis; HIV; Macrophage activation; Monokines; Neurologic damage

Indexed keywords

MACROPHAGE ACTIVATING FACTOR; QUINOLINIC ACID; QUINOLINIC ACID DERIVATIVE; HLA ANTIGEN CLASS 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AIDS RELATED COMPLEX; BRAIN; HIV ASSOCIATED DEMENTIA; HUMAN; IMMUNOLOGY; MACROPHAGE ACTIVATION; OPPORTUNISTIC INFECTION; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; CORRELATION FUNCTION; HLA SYSTEM; HUMAN TISSUE; PATHOPHYSIOLOGY;

ACQUIRED IMMUNODEFICIENCY SYNDROME; AIDS DEMENTIA COMPLEX; AIDS-RELATED OPPORTUNISTIC INFECTIONS; BRAIN; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGE-ACTIVATING FACTORS; OPPORTUNISTIC INFECTIONS; QUINOLINIC ACID; QUINOLINIC ACIDS;

EID: 0029778342     PISSN: 10697438     EISSN: None     Source Type: Journal    
DOI: 10.1300/J128v01n02_01     Document Type: Article

References (42)

1. Achim, C.L., M.P. Heyes, and C.A. Wiley. Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains. Journal of Clinical Investigation 91 (1993): 2769-75.
2. Achim, C.L., K.M. Morey, and C.A. Wiley. Expression of major histocompatibility complex and HIV antigens within the brains of AIDS patients. AIDS 5 (1991): 535-541.
3. Achim, C.L., R. Wang, D.K. Miners, and C.A. Wiley. Brain viral burden in HIV infection. Journal of Neuropathology & Experimental Neurology 53 (1994): 284-94.
4. Benveniste, E.N. Cytokine circuits in brian. Implications for AIDS dementia complex. [Review]. Research Publications. Association for Research in Nervous & Mental Disease (1994) 72:71-88.
5. Buzy, J., D.E. Brenneman, C.B. Pert, A. Martin, A. Salazar, and M.R. Ruff. Potent gp 120-like neurotoxic activity in the cerebrospinal fluid of HIV-infected individuals is blocked by peptide T. Brain Research 598 (1992): 10-8.
6. Campbell, I.L., C.R. Abraham, E. Masliah, P. Kemper, J.D. Inglis, M.B. Oldstone, and L. Mucke. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proceedings of the National Academy of Sciences of the United States of America 90 (1993): 10061-5.
7. Cupp, C., J.P. Taylor, K. Khalili, and S. Amini. Evidence for stimulation of the transforming growth factor beta 1 promoter by HlV-1 Tat in cells derived from CNS. Oncogene 8 (1993): 2231-6.
8. Frohman, E.M., V.S. Noort, and S. Gupta. Astrocytes and intracerebral immune responses. J. Clin. Immunol. 9 (1989): 1-9.
9. Geleziunas, R., H. M. Schipper, and M.A. Wainberg. Pathogenesis and therapy of HIV-1 infection of the central nervous system [editorial]. [Review] Aids 6 (1992): 1411-26.
10. Giulian, D., K. Vaca, and C.A. Noonan. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 250 (4987 1990): 1593-6.
11. Glowa, J.R., L.V. Panlilio, D.E. Brenneman, I. Gozes, M. Fridkin, and J.M. Hill. Learning impairment following intracerebral administration of the HIV envelope protein gpl20 or a VIP antagonist. Brain Res 570 (1-2 1992): 49-53.
12. Heyes, M.P. and S.P. Markey. Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations. Analytical Biochemistry 174 (1988): 349-359.
13. Heyes, M.P., K. Saito, and S.P. Markey. Human macrophages convert L-trypto-phan into the neurotoxin quinolinic acid. Biochem. J. 283 (1992): 633-635.
14. Kolson, D.L., J. Buchhalter, R. Collman, B. Hellmig, C.F. Farrell, C. Debouck, and F. Gonzalez-Scarano. HIV-1 tat alters normal organization of neurons and astrocytes in primary rodent brain cell cultures: RGD sequence dependence. Aids Research and Human Retroviruses 9 (1993): 677-85.
15. Kure, K., J.F. Llena, W.D. Lyman, R. Soeiro, K.M. Weidenheim, A. Hirano, and D.W. Dickson. Human immunodeficiency virus-1 infection of the nervous system: an autopsy study of 268 adult, pediatric, and fetal brains. Hum. Pathol. 22(1991): 700-710.
16. Levy, R.M., D.E. Bredesen, and M.L. Rosenblum. Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. J. Neurosurg. 62 (1985): 475-495.
17. Lipton, S.A. HIV-related neurotoxicity. Brain Pathology 1 (1991): 193-199.
18. Lipton, S.A. Models of neuronal injury in AIDS: another role for the NMDA receptor? [see comments]. Trends in Neurosciences 15 (1992): 75-9.
19. Lipton, S.A., N.J. Sucher, P.K. Kaiser, and E.B. Dreyer. Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity. Neuron 7 (1991): 111-8.
20. Masliah, E., C.L. Achim, N. Ge, R. Deteresa, R.D. Terry, and C.A. Wiley. Spectrum of HIV-associated neocortical damage. Ann. Neurol. 32 (1992a): 85-93.
21. Masliah, E., N. Ge, C.L. Achim, L.A. Hansen, and C.A. Wiley. Selective neuronal vulnerability in HIV encephalitis. Journal of Neuropathology & Experimental Neurology 51 (1992b): 585-93.
22. Masliah, E., N. Ge, M. Morey, R. Deteresa, R.D. Terry, and C.A. Wiley. Cortical dendritic pathology in human immunodeficiency virus encephalitis [see comments]. Lab. Invest. 66 (1992c): 285-291.
23. McCall, J.L., K. Yun, S. Funamoto, and B.R. Parry. In vivo immunohistochemical identification of tumor necrosis factor/cachectin in human lymphoid tissue. Am. J. Pathol. 135 (1989): 421-425.
24. Merrill, J.E. and l.S. Chen. HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease. Faseb J 5 (10 1991): 2391-7.
25. Merrill, J.E., Y. Koyanagi, J. Zack, L. Thomas, F. Martin, and l.S. Chen. Induction of interleukin-1 and tumor necrosis factor alpha in brain cultures by human immunodeficiency virus type 1. J. Virol. 66 (1992): 2217-2225.
26. Molina, J.M., R. Schindler, R. Ferriani, M. Sakaguchi, E. Vannier, C.A. Dinarello, and J.E. Groopman. Production of cytokines by peripheral blood monocytes/ macrophages infected with human immunodeficiency virus type 1 (HIV-1). J Infect Dis 161 (1990): 888-93.
27. Porwit, A., C. Parravicini, A.L. Petren, T. Barkhem, G. Costanzi, S. Josephs, and P. Biberfeld. Cell association of HIV in AIDS-related encephalopathy and dementia. Apmis 97 (1989): 79-90.
28. Price, R.W., J.J. Sidtis, and B.J. Brew. AIDS dementia complex and HIV-1 infection: A view from the clinic. Brain Pathology 1 (1991): 155-162.
29. Sabatier, J.M., E. Vives, K. Mabrouk, A. Benjouad, H. Rochat, A. Duval, B. Hue, and E. Bahraoui. Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1. Journal of Virology 65 (1991): 961-7.
30. Savio, T. and G. Levi. Neurotoxicity of HIV coat protein gpl20, NMDA receptors, and protein kinase C: a study with rat cerebellar granule cell cultures. Journal of Neuroscience Research 34 (3 1993): 265-72.
31. Taylor, J.P., R. Pomerantz, O. Bagasra, M. Chowdhury, J. Rappaport, IC. Khalili, and S. Amini. TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation. Embo J 11 (1992): 3395-403.
32. Toggas, S.M., E. Masliah, E.M. Rockenstein, G.F. Rail, C.R. Abraham, and L. Mucke. Central nervous system damage produced by expression of the HIV-1 coat protein gp!20 in transgenic mice [see comments]. Nature 367 (6459 1994): 188-93.
33. Tyor, W.R., J.D. Glass, N. Baumrind, J.C. McArthur, J.W. Griffin, P.S. Becker, and D.E. Griffin. Cytokine expression of macrophages in HIV-1-associated vacuolar myelopathy. Neurology 43 (1993): 1002-9.
34. Tyor, W.R., J.D. Glass, J.W. Griffin, P.S. Becker, J.C. McArthur, L. Bezman, and D. E. Griffin. Cytokine expression in the brain during the acquired immunodeficiency syndrome. Ann Neurol 31 (1992): 349-60.
35. Vitkovic, L., G.P. Wood, E.O. Major, and A.S. Fauci. Human astrocytes stimulate HIV-1 expression in a chronically infected promonocyte clone via interleu-kin-6. Aids Research & Human Retroviruses 1 (9 1991): 723-7.
36. Wahl, S.M., J.B. Allen, F.N. McCartney, K. Me Morganti, T. Kossmann, L. Ellingsworth, U.E. Mai, S.E. Mergenhagen, and J.M. Orenstein. Macrophage-and astrocyte-derived transforming growth factor beta as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome. J Exp Med 173 (1991): 981-91.
37. Weis, S., H. Haug, and H. Budka. Neuronal damage in the cerebral cortex of AIDS brains: a morphometric study. Acta Neuropathol (Berl) 85 (1993): 185-9.
38. Wesselingh, S.L., C. Power, J.D. Glass, W.R. Tyor, J.C. McArthur, J.M. Farber, J.W. Griffin, and D.E. Griffin. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann Neurol 33 (1993): 576-82.
39. Wiley, C.A. and C.L. Achim. HIV encephalitis is the pathological correlate of dementia in AIDS [published erratum appears in Ann Neurol (Jan 1995) 37(1): 140. Annals of Neurology (1994) 36: 673-676.
40. Wiley, C.A., C.L. Achim, R.D. Schrier, M.P. Heyes, J.A. McCutchen, and I. Grant. Relationship of CSF immune activation associated factors to HIV encephalitis. AIDS 6 (1992): 1299-1307.
41. Wiley, C.A., E. Masliah, M. Morey, C. Lemere, R. Deteresa, M. Grafe, L. Hansen, and R. Terry. Neocortical damage during HIV infection. Ann. Neurol. 29 (1991): 651-657.
42. Wiley, C.A., R.D. Schrier, J.A. Nelson, EW. Lampert, and M.B.A. Oldstone. Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc. Natl. Acad. Sci. USA 83 (1986): 7089-7093.