The pathogenic role of T lymphocytes in vasculitis

Sarcoidosis Vasculitis and Diffuse Lung Disease

Volumn 13, Issue 3, 1996, Pages 217-220

  Weyand, Cornelia M ^a   Goronzy, Jörg J ^a  

^a MAYO CLINIC   (United States)

Author keywords

Pathogenesis; T lymphocytes; Vasculitis

Indexed keywords

ARTERY WALL; GENETIC SUSCEPTIBILITY; GIANT CELL ARTERITIS; HUMAN; INFLAMMATION; LYMPHOCYTIC INFILTRATION; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR; SHORT SURVEY; T LYMPHOCYTE; VASCULITIS;

ANIMALS; HLA-DR ANTIGENS; HUMANS; MICE; MICE, SCID; RISK FACTORS; T-LYMPHOCYTES; TEMPORAL ARTERITIS; VASCULITIS;

EID: 0029778274     PISSN: 11240490     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (9)

1. Weyand CM, Hicok KC, Hunder GG, Goronzy JJ: The HLA-DRB1 locus as a genetic component in giant cell arteritis. Mapping of a disease-linked sequence motif to the antigen binding site of the HLA-DR molecule. J Clin Invest 1992; 90: 2355-2361.
2. Weyand CM, Goronzy JJ: Molecular approaches toward pathological mechanisms in giant cell arteritis and Takayasu's arteritis. Curr Opin Rheumatol 1995; 7: 30-36.
3. Weyand CM, Hicok KC, Hunder GG, Goronzy JJ: Tissue cytokine patterns in polymyalgia rheumatica and giant cell arteritis. Ann Intern Med 1994; 121: 484-491.
4. + cells in giant cell arteritis. Evidence for two components of the disease. J Clin Invest 1994; 94: 1134-1140.
5. Weyand CM, Schönberger J, Oppitz U, Hunder NNH, Hicok KC, Goronzy JJ: Distinct vascular lesions in giant cell arteritis share identical T cell clonotypes. J Exp Med 1994; 179: 951-960.
6. Martinez-Taboada VM, Hunder NNH, Weyand CM, Goronzy JJ: Recognition of tissue residing antigen by T cells in vasculitic lesions of giant cell arteritis. Submitted.
7. Wagner AD, Björnsson J, Bartley GB, Goronzy JJ, Weyand CM: Interferon gamma producing T cells in giant cell vasculitis represent a minority of tissue infiltrating cells and are located distant from the site of pathology. Am J Pathol. In press.
8. Weyand CM, Goronzy JJ: Giant cell arteritis as an antigen driven disease. Rheum Dis Clin North Amer 1995; 21(4): 1027-1039.
9. Brack A, Martinez-Taboada VM, Younge B, Weyand CM, Goronzy JJ: Selection of disease relevant T cells in arteries with giant cell vasculitis engrafted into severe combined immunodeficiency mice. Submitted.