Evaluation of human transferrin radiolabeled with N-succinimidyl 4- [fluorine-18](fluoromethyl) benzoate

Journal of Nuclear Medicine

Volumn 37, Issue 8, 1996, Pages 1408-1412

  Aloj, Luigi ^a   Lang, Lixin ^a   Jagoda, Elaine ^a   Neumann, Ronald D ^a   Eckelman, William C ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

fluorine 18; gallium 67; iron metabolism; neoplasms; transferrin

Indexed keywords

FLUORINE 18; GALLIUM 67; SUCCINIMIDE DERIVATIVE; TRANSFERRIN;

ARTICLE; BINDING AFFINITY; CANCER CELL; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSPORT; DIAGNOSTIC IMAGING; HUMAN; HUMAN CELL; IRON METABOLISM; ISOTOPE LABELING; PRIORITY JOURNAL;

BENZOATES; CITRATES; CITRIC ACID; EVALUATION STUDIES; FLUORINE RADIOISOTOPES; GALLIUM RADIOISOTOPES; HUMANS; IODINE RADIOISOTOPES; ISOTOPE LABELING; SUCCINIMIDES; TOMOGRAPHY, EMISSION-COMPUTED; TRANSFERRIN; TUMOR CELLS, CULTURED;

EID: 0029777533     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Eckelman WC. The application of receptor theory to receptor-binding and enzyme-binding oncologic radiopharmaceuticals. Nucl Med Biol 1994;21:759-769.
2. Weinberg ED. Iron withholding: a defense against infection and neoplasia. Physiol Rev 1984;64:65-102.
3. Reichard P, Ehrenberg A. Ribonucleotide reductase: a radical enzyme. Science 1983;221:514-519.
4. Wrigglesworth J, Baum H. The biochemical functions of iron. In: Jacobs A, Worwood M, eds. Iron in biochemistry and medicine. London, England: Academic Press; 1980:29-86.
5. Klausner R, Renswoude JV, Ashwell G, et al. Receptor-mediated endocytosis of transferrin in K562 cells. J Biol Chem 1983;258:4715-4724.
6. Dautry-Varsat A, Ciechanover A, Lodish H. pH and the recycling of transferrin during receptor-mediated endocytosis. Proc Natl Acad Sci USA 1983;80:2258-2262.
7. Omary MB, Trowbridge IS, Minowada J. Human cell-surface glycoprotein with unusual properties. Nature 1980;286:888-891.
8. Sutherland R, Delia D, Schneider C, et al. Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. Proc Natl Acad Sci USA 1981;78:4515-4519.
9. Larson S, Rasey J, Allen D, Nelson N. A transferrin-mediated uptake of gallium-67 by EMT-6 sarcoma. 1. Studies in tissue culture. J Nucl Med 1979;20:837-842.
10. Larson S, Rasey J, Allen D, et al. Common pathway for tumor cell uptake of gallium-67 and iron-59 via a transferrin receptor. J Natl Cancer Inst 1980;64:41-53.
11. Harris W, Chen Y, Wein K. Equilibrium constants for the binding of Indium(III) to human serum transferrin. Inorg Chem 1994;33:4991-4998.
12. Brunetti A, Blasberg R, Finn R, Larson S. Gallium-transferrin as a macromolecular tracer of vascular permeability. Nucl Med Biol 1988;15:665-672.
13. Chitambar CR, Zivkovic Z. Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin independent mechanisms. Cancer Res 1987;47:3929-3934.
14. Staker B, Graham M, Evans M. Effect of bicarbonate on stability of the gallium-transferrin complex. J Nucl Med 1991;32:1439-1441.
15. 18F]-N-succinimidyl 4-(fluoromethyl)benzoate for protein labeling. Appl Radiat Isot 1994;45:1155-1163.
16. Aloj L, Lang L, Eckelman WC. Fluorine-18-labeled transferrin for measuring tumor metabolism [Abstract]. J Nucl Med 1995;36(Suppl):38P.
17. Salcedo T, Fleit H. Plasma membrane and intracellular pools of transferrin receptors decline during in vitro cultivation of U937 cells. Cell Prolif 1991;24:383-401.
18. Sundstrom C, Nilsson K. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer 1976;17:565-577.
19. Munson P, Rodbard D. LIGAND: a versatile computerized approach for characterization of ligand binding systems. Anal Biochem 1980;107:220-239.
20. Karin M, Mintz B. Receptor-mediated endocytosis of transferrin in developmentally totipotent mouse teratocarcinoma stem cells. J Biol Chem 1981;256:3245-3252.
21. Graham MM. Parameter optimization programs for positron emission tomography data analysis [Abstract]. J Nucl Med 1992;33(Suppl):1069.
22. Klausner R, Ashwell G, Renswoude JV, et al. Binding of apotransferrin to K562 cells: explanation of the transferrin cycle. Proc Natl Acad Sci USA 1983;80:2263-2266.
23. Otsuki H, Brunetti A, Owens E, et al. Comparison of iron-59, indium-111 and gallium-68 transferrin as a macromolecular tracer of vascular permeability and the transferrin receptor. J Nucl Med 1989;30:1676-1685.
24. Van Leeuwen-Stok A, Drager A, Schuurhuis G, et al. Gallium-67 in the human lymphoid cell line U-715: uptake, cytotoxicity and intracellular localization. Int J Radiat Biol 1993;64:749-759.
25. Budinger T. Physical attributes of single-photon tomography. J Nucl Med 1980;21: 579-592.