Alternative therapies for children with brain stem gliomas: Immunotherapy and gene therapy

Pediatric Neurosurgery

Volumn 24, Issue 4, 1996, Pages 217-222

  Packer, Roger J ^a,b,c  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Brain stem gliomas; Brain tumors; Gene therapy; Immunotherapy

Indexed keywords

BCG VACCINE; BETA INTERFERON; INTERLEUKIN 2; LEVAMISOLE; NIMUSTINE;

ARTICLE; BRAIN TUMOR; CHILDHOOD; GENE THERAPY; GLIOMA; HUMAN; IMMUNOTHERAPY; PRIORITY JOURNAL; PROGNOSIS; RADIOTHERAPY;

EID: 0029776751     PISSN: 10162291     EISSN: 14230305     Source Type: Journal    
DOI: 10.1159/000121041     Document Type: Article

References (21)

1. Packer RJ., Nicholson MS, Johnson DL, Vezina LG: Dilemmas in the management of childhood brain tumors: Brain stem gliomas., Pc-diatr Ncurosurg 1992:17:37-43.
2. Packer RJ, Kramer HD, Ryan J: Biologic and immune modulating agents in the treatment of childhood brain tumors., Neurol Gin 1992;9: 405-422.
3. Allen JC, Hayes R: Selected Immunotherapy Studies of the Interferons and IL-S/LAK., in Brain Tumor Children: Principles of Diagnosis and Treatment., New York, Raven Press, 1994, pp 161-175.
4. Gillespie GY, Mahaley MS: Biological response modifier therapies for patients with malignant gliomas; in Thomas DGT (ed): Neuro-Oncology: Primary Malignant Brain Tumors., London., Arnold., 1990., pp 242-282.
5. Maddow A, Alexander P: Immunological method of increasing the sensitivity of primary sarcomas to local irradiation with x-rays., Lancet 1994:Vol i:452-455.
6. Mahaley MS Jr., Stcinbok P., Aronin P, et al: Immunobiology of primary intracranial tumors., 7., Active immunization of patients with anaplastic glioma cells: A pilot study., J Ncurosurg 1983:59:201-207.
7. Ibayashi Y, Yamak T, Kawahara T, Effect of local administration of lymphokine-acti-vated killer cells and interlcukin-IL-2 on malignant glioma patients., Neurol Med Chir (Tokyo) 1993:33/7:448-457.
8. Jcffes EW, Beamer YB, Jacques S: Theory of recurrent high-grade gliomas with surgery, and autologous mitogen activated IL-2 stimulated (MAK) lymphocytes, I, Enhancement of MAK lytic activity and cytokine production by PMA and clinical use of PMA., J Neurooncol 1993; 15/2:141-155.
9. Merchant R, Ellison M., Young M: Immunotherapy for malignant glioma using human recombinant interlcukin-2 and activated autologous lymphocytes., J Neurooncol 1990:8:173-188.
10. Epenclos AA, Courtnay-Luck N., Pickering D., et al: Antibody guided irradiation of brain glioma by arterial infusion of radioactive monoclonal antibody against epidermal growth factor receptor and blood group A antigen., BMJ 1985:290:1463-1466.
11. Lashford L., Mosley RP, Benjamin JC, et al: Antibody targeted irradiation for leptomenin-geal neoplasm: Current status., J Neurooncol 1989;7:517.
12. Lee Y, Bigner DD: Aspect of immunobiology and immunotherapy and the uses of monoclonal antibodies and biologic immune modifiers in human gliomas., Neurol Clin 1985;3:901-917.
13. Mahaley MS., Urso MB., Whaley RA., et al: Immunobiology of primary intracranial tumors., 10., Therapeutic efficacy of interferon in the treatment of recurrent gliomas., J Ncurosurg 1985;63:719-725.
14. Mahaley MS Jr, Gillespie GY: Immunologic consideration of patients with brain tumors; in Walker MD (ed): Oncology of the Nervous System., Boston, Nijhoff, 1983, pp 151-165.
15. Nagai M, Arai T: Interferon therapy for malignant brain tumours: Present and future., No Shinkci Geka 1982:10:463-476.
16. Nagai M, Arai T: Clinical effect of interferon in malignant brain tumors., Ncurosurg Rev 1984; 7:55-64.
17. Yung WKA., Prados M., Levin VA., et al: Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: A phase 1/11 study., J Clin Oncol 1991;9:1945-1949.
18. Allen J., Packer R, Bleger A, et al: Recombinant beta-interferon (Bctaseron): A phase 1-II trial in children with recurrent brain tumors., J Clin Oncol 1991:9:783-788.
19. Wakabayashi T, Yoshida J, Mizuno M., el al: Effectiveness of interferon-B, ACNU, and radiation therapy in pediatric patients with brainstem glioma., Neurol Med Chir (Tokyo) 1992:32:942-946.
20. Culver KW, Ram Z, Wallbridgc S, In vivo gene transfer with retro-viral producer cells for treatment of experimental brain tumors., Science 1992;256:1550-1552.
21. Mooken FL, Wells JM: Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors., J Natl Cancer Inst 1990;82:297-300