Tumor growth and tumor radiosensitivity in mice given myeloprotective doses of fibroblast growth factors

Journal of the National Cancer Institute

Volumn 88, Issue 19, 1996, Pages 1399-1404

  Ding, Ivan ^a   Huang, Kundi ^a   Snyder, Matthew L ^a   Cook, John ^a   Zhang, Lurong ^a   Wersto, Nancy ^a   Okunieff, Paul ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; RECOMBINANT PROTEIN;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BONE MARROW TOXICITY; CANCER RADIOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL NEOPLASM; FEMALE; INTRATUMORAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METASTASIS; MOUSE; NONHUMAN; RADIATION INJURY; RADIOSENSITIVITY; TUMOR GROWTH;

EID: 0029776482     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/88.19.1399     Document Type: Article

References (22)

1. Gospodarowicz D, Neufeld G, Schweigerer L. Fibroblast growth factor. Mol Cell Endocrinol 1986;46:187-204.
2. Thomas KA, Gimenes-Gallego G. Fibroblast growth factors: broad spectrum mitogens with potent angiogenic activity. Trends Biochem Sci 1986;11:81-6.
3. Thomas KA. Fibroblast growth factors. FASEB J 1987;1:434-40.
4. Gallicchio VS, Hughes NK, Hulette BC, DellaPuca R, Noblitt L. Basic fibroblast growth factor (bFGF) induces early- (CFU-s) and late-stage hematopoietic progenitor cell colony formation (CFU-gm, CFU-meg, and BFU-e) by synergizing with GM-CSF, Meg-CSF, and erythropoietin, and is a radioprotective agent in vitro. Int J Cell Cloning 1991;9: 220-32.
5. Gallicchio VS, DellaPuca R, Hulette BC, Hughes N, Messino MJ, Doukas MA. Basic fibroblastic growth factor (B-FGF) stimulates the proliferation of uncommitted hematopoietic progenitors and is a radioprotective agent in vitro. Exp Hematol 1989;17:203a.
6. Okunieff P, Abraham EH, Moini M, Snyder ML, Goe TR, Capogrossi MC, et al. Basic fibroblast growth factor radioprotects bone marrow and not RIF1 tumor. Acta Oncol 1995:34:435-8.
7. Okunieff P, Wu T, Huang K, Ding I. Differential radioprotection of three mouse strains by basic or acidic fibroblast growth factor. Br J Cancer 1996;74:S105-S108.
8. Haimovitz-Friedman A, Balaban N, McLoughlin M, Ehleiter D, Michaeli J, Vlodavsky I, et al. Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis. Cancer Res 1994;54:2591-7.
9. Fuks Z, Persaud RS, Alfieri A, McLoughlin M, Ehleiter D, Schwartz JL, et al. Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res 1994; 54:2582-90.
10. Tee PG, Travis EL. Basic fibroblast growth factor does not protect against classical radiation pneumonitis in two strains of mice. Cancer Res 1995;55:298-302.
11. Moini M, Ding I, Cook J, et al. Basic fibroblast growth factor is a radioprotector in vivo. Proceedings of 43rd Radiation Research Meeting. Vol 1. 1995:abstr 128. Oak Brook (IL): Radiation Research Society, 1995.
12. 31P NMR, laser Doppler flowmetry, and intradermal angiogenesis. Radiat Oncol Invest 1994;1:346-60.
13. Cook JA, Glass J, Lebovics R, Bobo H, Pass H, DeLaney TF, et al. Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine. Cancer Res 1992;52:719-25.
14. Woolson RF. Statistical methods for the analysis of biomedical data. New York: Wiley, 1987.
15. Han ZC, Bellucci S, Wan HY, Caen JP. New insights into the regulation of megakaryocytopoiesis by haematopoietic and fibroblastic growth factors and transforming growth factor β1. Br J Haematol 1992; 81:1-5.
16. Dorie MJ, Bedarida G, Kallman RF. Protection by interleukin 1 against lung toxicity caused by cyclophosphamide and irradiation. Radiat Res 1991;128:316-9.
17. Bubenik J, Indrova M, Holas V. Anti-tumour efficacy of IL-1 and IL-2. Folia Biol (Praha) 1988;34:42-7.
18. Constine LS, Harwell S, Keng P, Lee F, Rubin P, Siemann D. Interleukin 1 alpha stimulates hemopoiesis but not tumor cell proliferation and protects mice from lethal total body irradiation, Int J Radiat Oncol Biol Phys 1991; 20:447-56.
19. Leith JT, Papa G, Quanranto L, Michelson S. Modification of the volumetric growth responses and steady-state hypoxic fractions of xenografted DLD-2 human colon carcinomas by administration of basic fibroblast growth factor or suramin. Br J Cancer 1992;66:345-8.
20. Gross JL, Herblin WF, Dusak BA, Czerniak P, Diamond MD, Sun T, et al. Effects of modulation of basic fibroblast growth factor on tumor growth in vivo. J Natl Cancer Inst 1993;85: 121-31.
21. Folkman J. Angiogenesis and breast cancer [editorial; comment]. J Clin Oncol 1994;12:441-3.
22. Grau C, Nordsmark M, Khalil AA, Horsman MR, Overgaard J. Effect of carbon monoxide breathing on hypoxia and radiation response in the SCCVII tumor in vivo. Int J Radiat Oncol Biol Phys 1994;29:449-54.