Inhibition of human cytochrome P450-3A isoforms by fluoxetine and norfluoxetine: In vitro and in vivo studies

Journal of Clinical Pharmacology

Volumn 36, Issue 9, 1996, Pages 792-798

  Greenblatt, D J ^a   Von Moltke, L L ^a   Schmider, J ^a   Harmatz, J S ^a   Shader, R I ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; ALPRAZOLAM; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CARBAMAZEPINE; CLONAZEPAM; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; DIAZEPAM; DRUG METABOLITE; ENZYME ANTIBODY; ERYTHROMYCIN; FLUOXETINE; HYDROCORTISONE; IMIPRAMINE; KETOCONAZOLE; MIDAZOLAM; NEFAZODONE; NORFLUOXETINE; SEROTONIN UPTAKE INHIBITOR; TEMAZEPAM; TERFENADINE; TESTOSTERONE; TRIAZOLAM; TROLEANDOMYCIN;

COMPETITIVE INHIBITION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; DRUG POTENCY; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; LIVER MICROSOME; METABOLIC INHIBITION; NOTE;

EID: 0029776066     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1552-4604.1996.tb04252.x     Document Type: Note

References (0)