Primary sensitization of human T lymphocytes by cytokine-cultured, peripheral blood monocytes

European Journal of Dermatology

Volumn 6, Issue 6, 1996, Pages 409-413

  Kobel, Mark A ^a   Limat, Alain ^a   Mauri, Davide ^b   Braathen, Lasse R ^a   Hunziker, Thomas ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Functional capacity; GM CSF; IL 4; Peripheral blood monocytes; Primary sensitizations; Trinitrophenyl

Indexed keywords

HLA DR ANTIGEN; INTERLEUKIN 4; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TETANUS TOXOID;

ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LANGERHANS CELL; MALE; MONOCYTE; NORMAL HUMAN; T LYMPHOCYTE;

EID: 0029774112     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Teunissen MBM. Dynamic nature and function of epidermal Langerhans cells in vivo and in vitro: a review, with emphasis on human Langerhans cells. Histocnem J 1992; 24: 697-716.
2. + progenitors in human bone marrow. J Immunol 1992; 149: 2681-8.
3. Caux C, Dezutter-Dambuyant C, Schmitt D, Banchereau J. GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature 1992; 360: 258-61.
4. Romani N, Gruner S, Brang D, Kämpgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch PO, Steinmann RM, Schuler G. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994; 180: 83-93.
5. Kasinrerk W, Baumruker T, Majdic O, Knapp W, Stockinger H. CDI molecule expression on human monocytes induced by granulocyte-macrophage colony-stimulating factor. J Immunol 1993; 150: 579-84.
6. Rossi G, Heveker N, Thiele B, Gelderblom H, Steinbach F. Development of a Langerhans phenotype from peripheral blood monocytes. Immunol Lett 1992; 31: 189-97.
7. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J Exp Med 1994; 179: 1109-18.
8. Gothelf Y, Hanau D, Tsur H, Sharon N, Sahar E, Cazenave J-P, Gazit E. T6 positive cells in the peripheral blood of burn patients: Are they Langerhans cell precursors? J Invest Dermatol 1988; 90: 142-8.
9. Moulon C, Péguet-Navarro J, Courtellemont P, Redziniak G, Schmitt D. In vitro primary sensitization and restimulation of hapten-specific T cells by fresh and cultured human epidermal Langerhans cells. Immunol 1994; 80: 373-9.
10. Kotz S, Johnson NL eds. Encyclopedia of Statistical Sciences. Band 8, New York: Wiley, 1988.
11. Romani N, Schuler G. The immunologic properties of epidermal Langerhans cells as a part of the dendritic cell system. Springer Semin Immunopathol 1992; 13: 265-79.
12. Ortmann B, Martin S, von Bonin A, Schiltz E, Hoschützky H, Weltzien HU. Synthetic peptides anchor T cell-specific TNP epitopes to MHC antigens. J Immunol 1992; 148: 1445-50.
13. Enk AH, Angeloni VL, Udey MC, Katz SI. An essential role for Langerhans cell-derived IL-1β in the initiation of primary immune responses in skin. J Immunol 1993; 150: 3698-704.