Adaptive changes in the acute haemodynamic effects of cilazapril during chronic treatment. Comparison with long-term clinical effect

European Journal of Clinical Pharmacology

Volumn 50, Issue 6, 1996, Pages 433-441

  Larsen, J ^a   Sykulski, R ^b   Jensen, G ^a   Dossegger L ^c   Trimarco, B ^d   Moccetti, T ^e   Glogar, D ^f   Schelling, A ^g   Bosma, A H ^h  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AMAGER HOSPITAL   (Denmark)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

^d Direttore Cattedra di Nefrologia   (Italy)

^e Ospedale Civico Lugano   (Switzerland)

^f MEDICAL UNIVERSITY OF VIENNA   (Austria)

^g Afd Heelkunde   (Netherlands)

^h Sint Joseph Ziekenhuis   (Netherlands)

Author keywords

ACE inhibition; Cilazapril; Congestive heart failure; Exercise; Haemodynamics; Long term

Indexed keywords

CILAZAPRIL; DIGITALIS; DIURETIC AGENT; PLACEBO;

ADAPTATION; ADULT; AGED; ARTERIAL PRESSURE; ARTICLE; CARDIOGENIC SHOCK; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DYSPNEA; ELECTROCARDIOGRAM; EXERCISE TOLERANCE; FEMALE; HEART OUTPUT; HEMODYNAMICS; HUMAN; LUNG CAPILLARY PRESSURE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; TABLET; TACHYCARDIA;

ADULT; AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CILAZAPRIL; DOUBLE-BLIND METHOD; FEMALE; HEART FAILURE, CONGESTIVE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIDDLE AGED;

EID: 0029773388     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050137     Document Type: Article

References (36)

1. Consensus trial study group (1987) Effect of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (Consensus). N Engl J Med 316: 1429-1435
2. The SOLVD Investigators (1991) Effects of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 325: 293-302
3. Cohn JN, Johnson G, Cobb F, Francis G, Tristani F, Smith R, Dunkman WB, Loeh H, Wong M (1991) A comparison of enalapril with hydralazine-isosor3bide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 325: 303-310
4. SAVE investigators (1992) Effects of Captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 327: 669-677
5. The captopril Multicenter Research Group (1983) A placebo-controlled trial of captopril in refractory chronic congestive heart failure, J Am Coll Cardiol 2: 755-763
6. Chalmers JP, West MJ, Cyran J, De-La-Torre D, Englert M, Kramar M, Lewis GR, Maranhao MF, Myburgh DP, Schuster P, et al. (1987) Placebo-controlled study of Lisinopril in CHF: A multicentre study. J Card Pharm 9 [Suppl 3]: 89-97
7. The CAPTOPRIL-DIGOXIN Multi-Centre Research Group (1988) Comparative effects of therapy with Captopril and Digoxin in patients with mild to moderate heart failure. JAMA 259: 539-544
8. Dössegger L, Aldor E, Baird MG, Braun S, Cleland JG, Donaldson R, Jansen LJ, Joy MD, Marin-Neto JA, Nogueira E, et al (1993) Influence of angiotensin converting enzyme inhibition on exercise performance and clinical symptoms in chronic heart failure: A multi-centre, double-blind, placebo controlled trial. European Heart J 14 (Suppl C): 18-23
9. Packer M, Medina N, Yushak M (1996) Comparative Immediate Haemodynamic and Hormonal Effects of Amrinone and Captopril in patients with severe chronic heart failure. Am J Med Sci 291: 8-15
10. Dickstein K, Aarsland T, Woie L, Abrahamsen AM, Fyhrquist F, Cummings S, Gomex HJ, Hagen E, Kristianson K (1986) Acute haemodynamic and hormonal effects of lisonopril (MK-521) in congestive heart failure. Am Heart J 112: 121-129
11. Sharpe DN, Douglas JE, Coxon RJ, Long B (1980) Low-dose eaptopril in chronic heart failure: Acute haemodynamic effects and long-term treatment. Lancet II: 1154-1157
12. The Captopril Multi-Centre Research Group (1985) A cooperative multi-centre study of captopril in congestive heart failure: Haemodynamic effects and lone-term response. Am Heart J 110: 439-447
13. Shaw TR, Duncan FM, Williams BC, Crichton E, Thomson SA, Davis JR, Rademaker K, Edwards GR (1985) Plasma free captopril concentrations during short and long-term treatment with oral captopril for heart failure. Br Heart J 54: 160-165
14. Packer M, Lee WH, Medina N, Yushak M (1985) Haemodynamic and clinical significance of the pulmonary vascular response to long-term captopril therapy in patients with severe chronic heart failure. J Am Coll Cardiol 6: 635-645
15. Sharpe DN, Murphy J, Coxon R, Hannan SF (1984) Enalapril in patients with chronic heart failure: A placebo-controlled, randomized, double-blind study. Circulation 70: 271-278
16. Webster MWI, Fitzpatrick MA, Hamilton EJ, Nicholls MG, Ikram H, Espiner EA, Wells JE (1985) Effects of enalapril on clinical status, biochemistry, exercise performance and hemodynamics in heart failure. Drugs 30 [Suppl 1]: 74-81
17. Gomez HJ, Cirillo VJ, Davies RO, Bolognese JA, Walker JF (1986) Enalapril in congestive heart failure: acute and chronic invasive haemodynamic evaluation. Int J Cardiol 11: 37-48
18. Mulligan IP, Fraser AG, Tirlapur V, Lewis MJ, Newcombe RG, Henderson AH (1988) A randomized cross-over study of enalapril in congestive heart failure: haemodynamic and hormonal effects during rest and exercise. Eur J Clin Pharmacol 34: 323-334
19. Stone CK, Uretsky BF, Linnemeier TJ, Shah PK, Amin DK, Snapinn SM, Rush JE, Langendorfer A, Liang CS (1989) Haemodynamic effects of lisinopril after long-term administration in congestive heart failure. Am J Cardiol 63: 567-570
20. Cleland JG, Dargie HJ, Ball SG, Gillen G, Hodsman GP, Morton JJ, East BW, Robertson I, Ford I, Robertson JI (1985) Effects of enalapril in heart failure: A double-blind study of effects on exercise performance, renal function, hormones and metabolic state. B Heart J 54: 305-312
21. Cleland JG, Dargie HJ, Hodsman GP, Ball SG, Robertson JI, Morton JJ, East BW, Robertson I, Murray GD, Gillen G (1984) Captopril in heart failure: A double-blind controlled trial. B Heart J 52: 530-535
22. Dzau VJ, Colucci WS, Williams GH, Corfman G, Meggs L, Hollenberg NK (1980) Sustained effectiveness of converting-enzyme inhibition in patients with severe congestive heart failure. N Engl J Med 302: 1373-1379
23. Lee WH, Packer M (1986) Prognostic importance of serum sodium concentration and its modification by converting enzyme inhibitors in patients with severe chronic heart failure. Circulation 73: 257-267
24. Cohn JN, Levine TB, Olivari MT, Garberg V, Lura D, Francis CS, Simon AB, Rector T (1984) Plasma norepinephrine us a guide to prognosis in patients with chronic congestive failure N Engl J Med 311: 819-823
25. Cleland JF, Oakley CM (1991). Vascular tone in heart failure: The neuroendocrine-therapeutic interface. Br Heart J 66: 264-267
26. Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L (1990) Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. Circulation 82: 1730-1736
27. Dössegger L, Nielsen T, Preston C, Arabatzis N (1994) Heart Failure Therapy with Cilazapril: An Overview. J Cardiovasc Pharmacol 24 [Suppl 3]: 38-41
28. Drexler H, Banhardt V, Meinertz T, Wollschlager H, Lehmann M. Just H (1989) Contrasting peripheral short-term and long-term effects of converting enzyme inhibition in patients with congestive heart failure. Circulation 79: 491-502
29. Kiowski W, Zuber H, Elsasser S, Erne P, Pfisterer M, Bukkart F (1991) Coronary vasodilation and improved myocardial lactate metabolism after angiotensin converting enzyme inhibition with cilazapril in patients with congestive heart failure. Am Heart J 110: 1382-1398
30. Kostuk W, Barr JW, Simon AL, Ross J (1973) Correlation between the chest film and hemodynamics in acute myocardial infarction. Circulation 48: 624-632
31. Packer M, Medina N, Yushak M (1985) Haemodynamic changes mimicking avasodilator drug response in absence of drug therapy after right heart catherizalion in patients with chronic heart failure. Circulation 71: 761-766
32. Packer M (1986) Comparison of captopril and enalapril in patients with severe chronic heart failure. N Engl J Med 315: 847-853
33. Warren SE, Smith HS, Janousek JP, Lanoue AS, Baim DS (1986) Microdose captopril titration in chronic congestive heart failure. Heart Failure. August/September: 185-189
34. Packer M (1985) Converting-enzyme inhibition for severe chronic heart failure: Views from a skeptic. Int J Cardiol 7: 111
35. Packer M, Medina N, Yushak M, Meller J (1983) Haemodynamic patterns of response during long-term captopril therapy for severe chronic heart failure. Circulation 68: 803-812
36. Cleland JG, Dargie HJ, McAlpine H, Ball SG, Morton JJ, Robertson I, Ford I (1985) Severe hypotension after first dose of enalapril in heart failure. Br Med J 291: 1309-1312