Cloning of the mucosal addressin MAdCAM-1 from human brain: Identification of novel alternatively spliced transcripts

Immunology and Cell Biology

Volumn 74, Issue 6, 1996, Pages 490-496

  Leung, E ^a   Greene, J ^b   Ni, J ^b   Raymond, L G ^b   Lehnert, K ^a   Langley, R ^a   Krissansen, G W ^a,c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b GLAXOSMITHKLINE   (United States)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

cDNA clones; cell adhesion; DNA sequence; expression; MAdCAM 1; protein structure

Indexed keywords

ADDRESSIN;

ARTICLE; BRAIN; DNA SEQUENCE; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; PEYER PATCH; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE; RNA SPLICING;

EID: 0029772015     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1038/icb.1996.81     Document Type: Article

References (29)

1. Briskin MJ, McEvoy LM, Butcher EC. MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1. Nature 1993; 363: 461-4.
2. Berlin C, Berg EL, Briskin MJ et al. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Celt 1994; 74: 185-95.
3. Yang Y, Sammar M, Harrison JEB et al. Construction and adhesive properties of a soluble MAdCAM-1-Fc chimera expressed in a baculovirus system: Phylogenetic conservation of receptor-ligand interaction. Scand. J. Immunol. 1995; 42: 235-47.
4. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994; 76: 301-14.
5. Streeter PR, Berg EL, Rouse BTN, Bargatze RF, Butcher EC. A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 1988; 331: 41-6.
6. Holzmann B, McIntyre BW, Weissman IL. Identification of a murine Peyer's patch-specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha. Cell 1989; 56: 37-46.
7. Hamann A, Andrew DP, Jablonski-Westrich D, Holzmann B, Butcher EC. Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo. J. Immunol. 1994; 152: 3282-93.
8. Issekutz TB. Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. J Immunol. 1991; 147: 4178-84.
9. Hanninen A, Taylor C, Streeter PR et al. Vascular addressins are induced on islet vessels during insulitis in nonobese diabetic mice, and are involved in lymphoid cell binding to islet endothelium. J. Clin. Invest. 1993; 92: 2509-15.
10. Yednock TA., Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 1992; 356: 63-6.
11. Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway CA. Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med 1993; 177: 57-68.
12. Yang Y, Harrison JEB, Print CG et al. Interaction of monocytoid cells with the mucosal addressin MAdCAM-1 via the integrins VLA-4 and LPAM-1. Immunol. Cell Biol. 1996 (in press).
13. Briskin MJ, Rott L, Butcher EC. Structural requirements for mucosal vascular addressin binding to its lymphocyte receptor α4β7. J. Immunol. 1996; 156: 719-26.
14. Berg EL, McEvoy LM, Berlin C, Bargatze RF, Butcher EC. L-selectin-mediated lymphocyte rolling on MAdCAM-1. Nature 1993; 366: 695-8.
15. Adams MD, Kerlavage AR, Fleischmann RD et al. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Nature 1995; 377: 3-17.
16. Adams MD, Kelley JM, Gocayne JD et al. Complementary DNA sequencing: expressed sequence tags and human genome project. Science 1991; 252: 1651-6.
17. Adams MD, Dubnick M, Kerlavage AR et al. Sequence identification of 2,375 human brain genes (comment). Nature 1992; 355: 632-4.
18. Choo KH, Filby G, Greco S, Lau Y-F, Kan, YW. Cosmid vectors for high efficiency DNA-mediated transformation and gene amplification in mammalian cells. Studies with the human growth hormone gene. Gene 1986; 46: 277-86.
19. Leung E, Mead PE, Yuan Q, Jiang W-M, Watson JD, Krissansen GW. The mouse beta 7 integrin gene promoter: Transcriptional regulation of the leukocyte integrins LPAM-1 and M290. Int. Immunol. 1993; 5: 551-8.
20. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J. Mol. Biol. 1990; 215: 403-10.
21. Toribara NW, Gum JR, Culhane PJ et al. MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism. J. Clin. Invest. 1991; 88: 1005-13.
22. Berg EL, Picker LJ, Robinson MK, Streeter PR, Butcher EC. Cellular and Molecular Mechanisms of Inflammation, Vol. 2. San Diego: Academic, 1991; 111-29.
23. Kraal G, Schornagel K, Streeter PR, Holzmann B, Butcher EC. Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen. Am. J. Path. 1995; 147: 763-71.
24. O'Neill JK, Butter C, Baker D et al. Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse. Immunology 1991; 72: 520-5.
25. Sampaio SO, Li X, Takeuchi M et al. Organization, regulatory sequences, and alternatively spliced transcripts of the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) gene. J. Immunol. 1995; 155: 2477-86.
26. Shyjan AM, Bertagnolli M, Kenney CJ, Briskin MJ. Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the α4β7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences. J. Immunol. 1996; 156: 2851-7.
27. Fontenot JD, Tjandra N, Bu D, Ho C, Montelaro RC, Finn OJ. Biophysical characterization of one-, two-, and three-tandem repeats of human mucin (muc-1) protein core. Cancer Res. 1993; 53: 5386-94.
28. Vos H, de Vries Y, Hilkens J. The mouse episialin (Muc1) gene and its promoter: rapid evolution of the repetitive domain in the protein. Biochem. Biophys. Res. Commun. 1991; 181: 121-30.
29. Shimizu Y, Shaw S. Cell adhesion. Mucins in the mainstream (comment). Nature 1993; 366: 630-1.