Comparison of effect of endothelin antagonism and angiotensin- converting enzyme inhibition on blood pressure and vascular structure in spontaneously hypertensive rats treated with N(ω)-nitro-L-arginine methyl ester: Correlation with topography of vascular endothelin-1 gene expression

Hypertension

Volumn 28, Issue 2, 1996, Pages 188-195

  Li, Jin S ^a   Deng, Li Y ^a   Grove, Kevin ^a   Deschepper, Christian F ^a   Schiffrin, Ernesto L ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

aorta; endothelium derived factor; nitric oxide; receptors, endothelin; resistance vessels

Indexed keywords

ARGININE METHYL ESTER; BOSENTAN; CILAZAPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE THERAPY; ARTICLE; DRUG EFFECT; DRUG MECHANISM; HYPERTENSION; MALIGNANT HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 0029767930     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.28.2.188     Document Type: Article

References (37)

1. Schiffrin EL. Endothelin: potential role in hypertension and vascular hypertrophy. Brief review. Hypertension. 1995;25:1135-1143.
2. Larivière R, Thibault G, Schiffrin EL. Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats. Hypertension. 1993;21: 294-300.
3. Larivière R, Day R, Schiffrin EL. Increased expression of endothelin-1 gene in blood vessels of deoxycorticosterone acetate-salt hypertensive rats. Hypertension. 1993;21:916-920.
4. Day R, Larivière R, Schiffrin EL. In situ hybridization shows increased endothelin-1 mRNA levels in endothelial cells of blood vessels of deoxycorticosterone acetate-salt hypertensive rats. Am J Hypertens. 1995;8:294-300.
5. Larivière R, Deng LY, Day R, Sventek P, Thibault G, Schiffrin EL. Increased endothelin-1 gene expression in the endothelium of coronary arteries and in the endocardium of DOCA-salt hypertensive rats. J Mol Cell Cardiol. 1995;27:2123-2131.
6. Schiffrin EL, Larivière R, Li J-S, Sventek P, Touyz RM. Deoxycorticosterone acetate plus salt induce overexpression of vascular endothelin-1 and severe vascular hypertrophy in spontaneously hypertensive rats. Hypertension. 1995;25(part 2):769-773.
7. Sventek P, Turgeon A, Garcia R, Schiffrin EL. Vascular and cardiac overexpression of endothelin-1 gene in 1-kidney one clip Goldblatt hypertensive rats but only in the late phase of 2-kidney, 1 clip Goldblatt hypertension. J Hypertens. 1996;14:57-64.
8. Sventek P, Li J-S, Grove K, Deschepper CF, Schiffrin EL. Vascular structure and expression of endothelin-1 gene in L-NAME-treated spontaneously hypertensive rats. Hypertension. 1996;27:49-55.
9. Li JS, Larivière R, Schiffrin EL. Effect of a nonselective endothelin antagonist on vascular remodeling in DOCA-salt hypertensive rats. Hypertension. 1994;24:183-188.
10. Schiffrin EL, Sventek P, Li J-S, Turgeon A, Reudelhuber T. Antihypertensive effect of bosentan, a mixed ETA/ETB endothelin receptor antagonist, in DOCA-salt spontaneously hypertensive rats. Br J Pharmacol. 1995;115:1377-1381.
11. Bird JE, Moreland S, Waldron TL, Powell JR. Antihypertensive effects of a novel endothelin-1 receptor antagonist in rats. Hypertension. 1995,25:1191-1195.
12. A receptor antagomst, in spontaneously hypertensive rats treated with DOCA-salt. Eur J Pharmacol. 1994;259:339-342.
13. Deng LY, Schiffrin EL. Effects of endothelin on resistance arteries of DOCA-salt hypertensive rats. Am J Physiol. 1992;262:H1782-H1787.
14. Deng LY, Schiffrin EL. Morphological and functional alterations of mesenteric small resistance arteries in early renal hypertension in the rat. Am J Physiol. 1991;261:H1171-H1177.
15. Larivière R, Sventek P, Thibault G, Schiffrin EL. Expression of endothelin-1 gene in blood vessels of adult spontaneously hypertensive rats. Life Sci. 1995;56:1889-1896.
16. Dene LY, Schiffrin EL. Effects of endothelin-1 and vasopressin on small arteries of spontaneously hypertensive rats. Am J Hypertens. 1992;5:817-822.
17. Li J-S, Schiffrin EL. Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist. Hypertension. 1995;25(part 1):495-500.
18. Li J-S, Schiffrin EL. Chronic endothelin receptor antagonist treatment of young spontaneously hypertensive rats. J Hypertens. 1995; 13:647-652.
19. Clozel M, Breu V, Gray GA, Kalina B, Löffler B-M, Burri K, Cassal J-M, Hirth G, Muller M, Neidhart W, Ramuz H. Pharmacological characterization of bosentan, a new potent orally active non-peptide endothelin receptor antagonist. J Pharmacol Exp Ther. 1994;270: 228-235.
20. Dene LY, Thibault G, Schiffrin EL. Effect of hypertension induced by nitric oxide synthase inhibition on structure and function of resistance arteries in the rat. Clin Exp Hypertens. 1993;15:527-537.
21. Li J-S, Schiffrin EL. Resistance artery structure and neuroeffector mechanisms in hypertension induced by inhibition of nitric oxide synthase. Am J Hypertens. 1994;7:996-1004.
22. Dunn WR Gardiner SM. No evidence of vascular remodeling during hypertension induced by chronic inhibition of nitric oxide synthase in Brattleboro rats. J Hypertens. 1995;13:849-857.
23. Schiffrin EL. Vascular structure in L-NAME-induced hypertension: methodological considerations for studies of small arteries in hypertension. J Hypertens. 1995;13:817-821. Editorial.
24. Jover B, Henzi A, Ventre F, Dupon M, Mimran A. Sodium and angiotensin in hypertension induced by long-term nitric oxide blockade. Hypertension. 1993;21:944-948.
25. Thybo NK, Korsgaard N, Eriksen S, Christensen KL, Mulvany MJ. Dose-dependent effects of perindopril on blood pressure and small-artery structure. Hypertension. 1994:23:659-666.
26. Brockway BP, Mills PA, Azar SH. A new method for continuous chronic recording of blood pressure, heart rate and activity in the rat via radiotelemetry. Clin Exp Hypertens A. 1991;13:885-895.
27. Sakurai T, Yanagisawa M, Inoue A, Ryan US, Kiura S, Mitsui Y, Goto K, Masaki T. cDNA cloning, sequencing analysis and tissue distribution of rat preproendothelin-1 mRNA. Biochem Biophys Res Commun. 1991;175:44-47.
28. Li JS, Schüren W, Touyz RM, Schiffrin EL. Increased survival and reduced vascular hypertrophy and blood pressure in malignant DOCA-salt SHR treated with an endothelin receptor antagonist. Hypertension. 1995;26:576. Abstract.
29. Bobik A, Grooms A, Millar JA, Mitchell A, Grinpukel S. Growth factor activity of endothelin on vascular smooth muscle. Am J Physiol. 1990;258:C408-C415.
30. Schiffers PMH, Fazzi GE, Van Ingen Schenau D, De Mey JGR. Effects of candidate autocrine and paracrine mediators on growth responses in isolated rat arteries. Arterioscler Thromb. 1994;14: 420-426.
31. Arnal JF, El Amrani A-I, Chatellier G, Ménard J, Michel J-B. Cardiac weight in hypertension induced by nitric oxide synthase blockade. Hypertension. 1993;22:380-387.
32. Schricker K, Scholz H, Hamann M, Clozel M, Krämer BK, Kurtz A. Role of endogenous endothelins in the renin system of normal and two-kidney, one clip rats. Hypertension. 1995;25:1025-1029.
33. Li J-S, Knafo L, Turgeon A, Garcia R, Schiffrin EL. Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats. Am J Physiol (Heart Circ Physiol). In press.
34. Clozel M. Mechanism of action of angiotensin converting enzyme inhibitors on endothelial function in hypertension. Hypertension. 1991;18(suppl II):II-37-II-42.
35. Kaufmann H, Oribe E, Oliver JA. Plasma endothelin during upright tilt: relevance for orthostatic hypotension. Lancet. 1991;338:1542-1545.
36. Hiwatari M, Abrahams JM, Saito T, Johnston CI. Contribution of vasopressin to the maintenance of blood pressure in deoxycorticosterone-salt induced malignant hypertension in spontaneously hypertensive rats. Clin Sci. 1986;70:191-198.
37. De Nucci G, Thomas R, D'Orléans-Juste P, Antunes E, Walder C, Warner TD, Vane JR. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. Proc Natl Acad Sci U S A. 1988;85:9797-9800.