5-bromo-2'-deoxyuridine stimulates the pituitary-adrenal axis in the rat: An effect blocked partially by endothelin-receptor antagonists

Journal of International Medical Research

Volumn 24, Issue 4, 1996, Pages 363-368

  Malendowicz, L K ^a   Nussdorfer, G G ^b,c  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

Author keywords

5 bromo 2' deoxyuridine; Endothelins; Pituitary adrenal axis; Rat; Steroid secretion

Indexed keywords

ALDOSTERONE; BROXURIDINE; CORTICOSTERONE; CORTICOTROPIN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DEXAMETHASONE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE;

ALDOSTERONE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; FEMALE; HYPOPHYSIS ADRENAL SYSTEM; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; RAT;

EID: 0029767923     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/030006059602400408     Document Type: Article

References (10)

1. Rubanyi GM, Polokoff MA: Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 1994; 46: 325-415.
2. Dolbeare F: Bromodeoxyuridine: a diagnostic tool in biology and medicine. Historical perspectives, histochemical methods and cell kinetics. Histochem J 1995; 27: 339-369.
3. Ihara M, Noguchi K, Saeki T, et al: Biological profiles of highly potent novel endothelin antagonists selective for the ETa receptor. Life Sci 1992; 50: 247-256.
4. Ishikawa K, Ihara M, Noguchi K, et al: Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788. Proc Natl Acad Sci USA 1994; 91: 4892-4896.
5. Malendowicz LK, Nussdorfer GG, Markowska A, et al: Effect of neurotensin-N on the pituitary-adrenocortical axis of dexamethasone-suppressed rats. Neuropeptides 1993; 24: 1-4.
6. Nussdorfer GG: Cytophysiology of the adrenal cortex. Int Rev Cytol 1986; 98: 1-405.
7. Mazzocchi G, Rebuffat P, Meneghelli V, et al: Effects of prolonged infusion with endothelin-1 on the function and morphology of rat adrenal cortex. Peptides 1990; 11: 767-772.
8. Naruse M, Naruse K, Demura H: Recent advances in endothelin research on cardiovascular and endocrine systems. Endocrine J 1994; 41: 491-507.
9. Kendal MD: The cell biology of cell death in the thymus. In: Thymus Update 3. (Kendal MD ed). Churchill, Switzerland, Harwood Academic Publisher, 1990; pp. 47-70.
10. Evans-Storms RB, Cidlowski JA: Regulation of apoptosis by steroid hormones. J Steroid Biochem Mol Biol 1995; 53: 1-8.