-
3
-
-
0019199109
-
Metabolism of acrylonitrile to cyanide: In vitro studies
-
Abreu M, Ahmed AE (1980). Metabolism of acrylonitrile to cyanide: in vitro studies. Drug Metab Dispos 8: 376 379
-
(1980)
Drug Metab Dispos
, vol.8
, pp. 376-379
-
-
Abreu, M.1
Ahmed, A.E.2
-
4
-
-
0019406020
-
Acrylonitrile: In vivo metabolism in rats and mice
-
Ahmed AE, Patel K (1981) Acrylonitrile: in vivo metabolism in rats and mice. Drug Metab Dispos 9: 219 222
-
(1981)
Drug Metab Dispos
, vol.9
, pp. 219-222
-
-
Ahmed, A.E.1
Patel, K.2
-
6
-
-
77957015641
-
Determination of DNA concentration with diphenylamine
-
Burton K (1968) Determination of DNA concentration with diphenylamine. Methods Enzymol 128: 163 165
-
(1968)
Methods Enzymol
, vol.128
, pp. 163-165
-
-
Burton, K.1
-
7
-
-
0026677629
-
Dose-dependent metabolism and dose setting in chronic studies
-
Bus JS. Reitz R (1992) Dose-dependent metabolism and dose setting in chronic studies. Toxicol Lett 64 65: 669-676
-
(1992)
Toxicol Lett
, vol.64-65
, pp. 669-676
-
-
Bus, J.S.1
Reitz, R.2
-
8
-
-
0025255243
-
Isotope dilution gas chromatography-mass spectrometry in the determination of benzene, toluene, styrene and acrylonitrile in mainstream cigarette smoke
-
Byrd GD, Fowler KW, Hicks RD, Lovette ME. Borgerding MF (1990) Isotope dilution gas chromatography-mass spectrometry in the determination of benzene, toluene, styrene and acrylonitrile in mainstream cigarette smoke. J Chromatogr 503: 359-368
-
(1990)
J Chromatogr
, vol.503
, pp. 359-368
-
-
Byrd, G.D.1
Fowler, K.W.2
Hicks, R.D.3
Lovette, M.E.4
Borgerding, M.F.5
-
9
-
-
0023088709
-
Cancer incidence and mortality among workers exposed to acrylonitrile
-
Chen JL, Walrath J, O'Berg MT, Burke CA, Pell S (1987) Cancer incidence and mortality among workers exposed to acrylonitrile. Am J Ind Med 11: 157 163
-
(1987)
Am J Ind Med
, vol.11
, pp. 157-163
-
-
Chen, J.L.1
Walrath, J.2
O'Berg, M.T.3
Burke, C.A.4
Pell, S.5
-
10
-
-
0023233965
-
The in vivo-in vitro hepatocyte assay for assessing DNA repair and DNA replication: Studies in CDI-mouse
-
Doolittle D.J. Muller G, Scribner HE (1987) The in vivo-in vitro hepatocyte assay for assessing DNA repair and DNA replication: studies in CDI-mouse. Food Chem Toxicol 25: 399-405
-
(1987)
Food Chem Toxicol
, vol.25
, pp. 399-405
-
-
Doolittle, D.J.1
Muller, G.2
Scribner, H.E.3
-
11
-
-
0021087583
-
In vivo interaction of acrylonitrile with macromolecules in rats
-
Farooqui MYH, Ahmed AE (1983) In vivo interaction of acrylonitrile with macromolecules in rats. Chem Biol Interact 47: 363-371
-
(1983)
Chem Biol Interact
, vol.47
, pp. 363-371
-
-
Farooqui, M.Y.H.1
Ahmed, A.E.2
-
13
-
-
0026664507
-
Carcinogen-mediated oxidant formation and oxidativc DNA damage
-
Frenkel K (1992) Carcinogen-mediated oxidant formation and oxidativc DNA damage. Pharmacol Ther 53: 127-166
-
(1992)
Pharmacol Ther
, vol.53
, pp. 127-166
-
-
Frenkel, K.1
-
15
-
-
0023179036
-
Use of in vivo in vitro unscheduled DNA synthesis for identification of organs-specific carcinogens
-
Furihata C, Matsushima T (1987) Use of in vivo in vitro unscheduled DNA synthesis for identification of organs-specific carcinogens. CRC Crit Rev Toxicol 17: 245 277
-
(1987)
CRC Crit Rev Toxicol
, vol.17
, pp. 245-277
-
-
Furihata, C.1
Matsushima, T.2
-
16
-
-
0021234737
-
Induction of unscheduled DNA synthesis in rat stomach mucosa by glandular stomach carcinogens
-
Furihata C, Yamawaki Y, Jin S, Moriya H, Kodama K, Matsuschima T, Ishikawa T, Takayama S, Nakadate M (1984) Induction of unscheduled DNA synthesis in rat stomach mucosa by glandular stomach carcinogens. J Natl Cancer Inst 72: 1327-1334
-
(1984)
J Natl Cancer Inst
, vol.72
, pp. 1327-1334
-
-
Furihata, C.1
Yamawaki, Y.2
Jin, S.3
Moriya, H.4
Kodama, K.5
Matsuschima, T.6
Ishikawa, T.7
Takayama, S.8
Nakadate, M.9
-
18
-
-
0020574194
-
Acrylonitrile-induced gastrointestinal hemorrhage and the effect of metabolism modulation in rats
-
Ghanayem BI, Ahmed AE (1983) Acrylonitrile-induced gastrointestinal hemorrhage and the effect of metabolism modulation in rats. Toxicol Appl Pharmacol 68: 290-296
-
(1983)
Toxicol Appl Pharmacol
, vol.68
, pp. 290-296
-
-
Ghanayem, B.I.1
Ahmed, A.E.2
-
19
-
-
0022504671
-
Prevention of acrylonitrile-induced gastrointestinal bleeding by sulfhydryl compounds, atropine and cimetidinc
-
Ghanayem BI. Ahmed AE (1986) Prevention of acrylonitrile-induced gastrointestinal bleeding by sulfhydryl compounds, atropine and cimetidinc. Res Commun Chem Pathol Pharmacol 53: 141-144
-
(1986)
Res Commun Chem Pathol Pharmacol
, vol.53
, pp. 141-144
-
-
Ghanayem, B.I.1
Ahmed, A.E.2
-
20
-
-
0022000828
-
Acrylonitrile-induced gastric mucosal necrosis: Role of gastric glutathione
-
Ghanayem BI, Boor PJ, Ahmed AE (1985) Acrylonitrile-induced gastric mucosal necrosis: role of gastric glutathione. J Pharmacol Exp Ther 232: 570 577
-
(1985)
J Pharmacol Exp Ther
, vol.232
, pp. 570-577
-
-
Ghanayem, B.I.1
Boor, P.J.2
Ahmed, A.E.3
-
21
-
-
0026019814
-
Effects of sulfhydryl modulation on ethyl acrylate-induced forestomach toxicity
-
Ghanayem BI, Maronpot RR, Mathews HB (1991) Effects of sulfhydryl modulation on ethyl acrylate-induced forestomach toxicity. Toxicol Lett 55: 215-221
-
(1991)
Toxicol Lett
, vol.55
, pp. 215-221
-
-
Ghanayem, B.I.1
Maronpot, R.R.2
Mathews, H.B.3
-
22
-
-
0028271998
-
Mechanisms of formation of DNA adducts from ethylene dihalides, vinyl halides. and arylamines
-
Guengerich FP (1994) Mechanisms of formation of DNA adducts from ethylene dihalides, vinyl halides. and arylamines. Drug Metab Rev 26: 47-66
-
(1994)
Drug Metab Rev
, vol.26
, pp. 47-66
-
-
Guengerich, F.P.1
-
23
-
-
0026035519
-
Role of human cytochrome P-450 II E1 in the oxidation of many low molecular weight cancer suspects
-
Guengerich FP, Kim D-H. Iwasaki M (1991) Role of human cytochrome P-450 II E1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4: 168-179
-
(1991)
Chem Res Toxicol
, vol.4
, pp. 168-179
-
-
Guengerich, F.P.1
Kim, D.-H.2
Iwasaki, M.3
-
24
-
-
0016205281
-
Routine gas Chromatographic component profiling of cigarette smoke for identification of biologically significant constituents
-
Guerin MR, Olerich G, Horton AD (1974) Routine gas Chromatographic component profiling of cigarette smoke for identification of biologically significant constituents. J Chromatogr Sci 12: 385-391
-
(1974)
J Chromatogr Sci
, vol.12
, pp. 385-391
-
-
Guerin, M.R.1
Olerich, G.2
Horton, A.D.3
-
25
-
-
0028331715
-
Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione
-
Hiraishi H, Terano A, Ota S, Mutoh H, Sugimoto T. Harada T, Razandi M, Ivey KJ (1994) Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione. Gastroenterology 106: 1199-1207
-
(1994)
Gastroenterology
, vol.106
, pp. 1199-1207
-
-
Hiraishi, H.1
Terano, A.2
Ota, S.3
Mutoh, H.4
Sugimoto, T.5
Harada, T.6
Razandi, M.7
Ivey, K.J.8
-
26
-
-
0022497049
-
In vivo interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats
-
Hogy LL, Guengerich FP (1986) In vivo interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats. Cancer Res 46: 3932-3938
-
(1986)
Cancer Res
, vol.46
, pp. 3932-3938
-
-
Hogy, L.L.1
Guengerich, F.P.2
-
28
-
-
0028085519
-
Effect of glutathione depletion and inhibition of glucuronidation and sulfation on 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) metabolism, PhIP-DNA adduct formation and unscheduled DNA synthesis in primary rat hepatocytes
-
Kaderlik KR, Mulder GJ, Shaddock JG, Casciano DA, Teitel CH, Kadlubar FF (1994) Effect of glutathione depletion and inhibition of glucuronidation and sulfation on 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) metabolism, PhIP-DNA adduct formation and unscheduled DNA synthesis in primary rat hepatocytes. Carcinogenesis 15: 1711-1716
-
(1994)
Carcinogenesis
, vol.15
, pp. 1711-1716
-
-
Kaderlik, K.R.1
Mulder, G.J.2
Shaddock, J.G.3
Casciano, D.A.4
Teitel, C.H.5
Kadlubar, F.F.6
-
29
-
-
0003176132
-
Production of top 50 chemicals increased substantially in 1994
-
Kirschner EM (1995) Production of top 50 chemicals increased substantially in 1994. Chem Eng News April 10: 10-22
-
(1995)
Chem Eng News April
, vol.10
, pp. 10-22
-
-
Kirschner, E.M.1
-
30
-
-
0024998325
-
Dose response relationship and low dose extrapolation in chemical Carcinogenesis
-
Lutz WK(1990) Dose response relationship and low dose extrapolation in chemical Carcinogenesis. Carcinogenesis 11: 1243-1247
-
(1990)
Carcinogenesis
, vol.11
, pp. 1243-1247
-
-
Lutz, W.K.1
-
31
-
-
0028594069
-
Glutathione can rescue the inhibitory effects of nickel on DNA ligation and repair synthesis
-
Lynn S, Yew FH, Hwang J-W, Tseng M-J, Jan KY (1994) Glutathione can rescue the inhibitory effects of nickel on DNA ligation and repair synthesis. Carcinogenesis 15: 2811-2816
-
(1994)
Carcinogenesis
, vol.15
, pp. 2811-2816
-
-
Lynn, S.1
Yew, F.H.2
Hwang, J.-W.3
Tseng, M.-J.4
Jan, K.Y.5
-
32
-
-
0028304672
-
Recommendations for the performance of UDS tests in vitro and in vivo
-
Madle S, Dean SW, Andrae U, Brambilla G, Burlinson B. Doolittle DJ, Furihata C. Hertner T, McQueen CA, Mori H (1994) Recommendations for the performance of UDS tests in vitro and in vivo. Mutat Res 312: 263-285
-
(1994)
Mutat Res
, vol.312
, pp. 263-285
-
-
Madle, S.1
Dean, S.W.2
Andrae, U.3
Brambilla, G.4
Burlinson, B.5
Doolittle, D.J.6
Furihata, C.7
Hertner, T.8
McQueen, C.A.9
Mori, H.10
-
33
-
-
0017586264
-
Carcinogenicity bioassays on rats of acrylonitrile administered by inhalation and ingestion
-
Maltoni C, Ciliberti A, DiMaio V (1977) Carcinogenicity bioassays on rats of acrylonitrile administered by inhalation and ingestion. Med Lav 68: 401-411
-
(1977)
Med Lav
, vol.68
, pp. 401-411
-
-
Maltoni, C.1
Ciliberti, A.2
DiMaio, V.3
-
36
-
-
0004234130
-
-
Allyn and Bacon Publication, Boston
-
Morrison RT, Boyd RN (1963) Organic Chemistry. Allyn and Bacon Publication, Boston, pp 120-121 and pp 733-739
-
(1963)
Organic Chemistry
, pp. 120-121
-
-
Morrison, R.T.1
Boyd, R.N.2
-
37
-
-
0023280198
-
Urinary excretion of acrylonitrile and its metabolites in rats
-
Muller G, Verkoyen C, Soton N, Norpoth K (1987) Urinary excretion of acrylonitrile and its metabolites in rats. Arch Toxicol 60: 464-466
-
(1987)
Arch Toxicol
, vol.60
, pp. 464-466
-
-
Muller, G.1
Verkoyen, C.2
Soton, N.3
Norpoth, K.4
-
38
-
-
0025257587
-
Protective role of intracellular glutathione against ethanol-induced damage in cultured rat gastric mucosal cells
-
Mutoh H, Hiraishi H. Ota S, Yoshida H. Ivey KJ, Terano A, Sugimoto T (1990) Protective role of intracellular glutathione against ethanol-induced damage in cultured rat gastric mucosal cells. Gastroenterology 98: 1452-1459
-
(1990)
Gastroenterology
, vol.98
, pp. 1452-1459
-
-
Mutoh, H.1
Hiraishi, H.2
Ota, S.3
Yoshida, H.4
Ivey, K.J.5
Terano, A.6
Sugimoto, T.7
-
39
-
-
0027294789
-
Ability of N-methyl-N'-nitro-N-nitrosoguanidine, 4-nitroquinoline 1-oxide, dimethylnitrosamine, and NaCl to induce unscheduled DNA synthesis, stimulate replicative DNA synthesis, and produce DNA single-strand breaks in pyloric mucosa of rat stomach
-
Ohsawa K, Furihata C, Mori M, Ikui E (1993) Ability of N-methyl-N'-nitro-N-nitrosoguanidine, 4-nitroquinoline 1-oxide, dimethylnitrosamine, and NaCl to induce unscheduled DNA synthesis, stimulate replicative DNA synthesis, and produce DNA single-strand breaks in pyloric mucosa of rat stomach. Mulat Res 2: 307 319
-
(1993)
Mulat Res
, vol.2
, pp. 307-319
-
-
Ohsawa, K.1
Furihata, C.2
Mori, M.3
Ikui, E.4
-
40
-
-
0023676046
-
Effect of glutathione depletion on the irreversible association of acrylonitrile with tissue macromolecules after oral administration to rats
-
Pilon D, Roberts AE, Rickert DE (1988) Effect of glutathione depletion on the irreversible association of acrylonitrile with tissue macromolecules after oral administration to rats. Toxicol Appl Pharmacol 95: 311-320
-
(1988)
Toxicol Appl Pharmacol
, vol.95
, pp. 311-320
-
-
Pilon, D.1
Roberts, A.E.2
Rickert, D.E.3
-
41
-
-
0001124118
-
Results of a chronic toxicity and oncogenicity study in rats maintained on water containing acrylonitrile for 24 months
-
Quast JF, Humiston CG, Wade CE, Carreon RM, Hermann EA, Park CN, Schweiz BA (1981) Results of a chronic toxicity and oncogenicity study in rats maintained on water containing acrylonitrile for 24 months. Toxicologist 1: 129
-
(1981)
Toxicologist
, vol.1
, pp. 129
-
-
Quast, J.F.1
Humiston, C.G.2
Wade, C.E.3
Carreon, R.M.4
Hermann, E.A.5
Park, C.N.6
Schweiz, B.A.7
-
42
-
-
0025811996
-
Species comparison of acrylonitrile epoxidalion by microsomes from mice, rats, and humans: Relationship to epoxide concentrations in mouse and rat blood
-
Roberts AE, Kedderis GL, Turner MJ, Rickert DE, Swenberg JA (1991) Species comparison of acrylonitrile epoxidalion by microsomes from mice, rats, and humans: relationship to epoxide concentrations in mouse and rat blood. Carcinogenesis 12: 401-409
-
(1991)
Carcinogenesis
, vol.12
, pp. 401-409
-
-
Roberts, A.E.1
Kedderis, G.L.2
Turner, M.J.3
Rickert, D.E.4
Swenberg, J.A.5
-
44
-
-
0024605132
-
Effects of fasting and glutathione depletion on the GSH-dependent enzyme system in the gastrointestinal mucosa of the rat
-
Siegers CP, Bartels L, Riemann D (1989) Effects of fasting and glutathione depletion on the GSH-dependent enzyme system in the gastrointestinal mucosa of the rat. Pharmacology 38: 121-128
-
(1989)
Pharmacology
, vol.38
, pp. 121-128
-
-
Siegers, C.P.1
Bartels, L.2
Riemann, D.3
-
45
-
-
0021126833
-
In vitro, alkylation of calf thymus DNA by acrylonitrile. Isolation of cyanoethyl-adducts of guanine and thymine and carboxy-ethyl-adducts of adenine and cytosine
-
Solomon JJ, Cote IL, Wortman M, Decker K, Segal A (1984) In vitro, alkylation of calf thymus DNA by acrylonitrile. Isolation of cyanoethyl-adducts of guanine and thymine and carboxy-ethyl-adducts of adenine and cytosine. Chem Biol Interact 51: 167-190
-
(1984)
Chem Biol Interact
, vol.51
, pp. 167-190
-
-
Solomon, J.J.1
Cote, I.L.2
Wortman, M.3
Decker, K.4
Segal, A.5
-
46
-
-
0027323384
-
In vitro, reaction of 2-cyanoethylene oxide with calf thymus DNA
-
Solomon JJ, Singh US, Segal A (1993) In vitro, reaction of 2-cyanoethylene oxide with calf thymus DNA. Chem Biol Interact 88: 115-135
-
(1993)
Chem Biol Interact
, vol.88
, pp. 115-135
-
-
Solomon, J.J.1
Singh, U.S.2
Segal, A.3
-
47
-
-
0023640965
-
Increased respiratory burst of leukocytes in inflammatory bowel diseases: The analysis of free radical generation by using chemiluminescence probe
-
Suematsu M, Suzuki M, Kitahora T, Miura S, Suzuki K, Hibi T, Watanabe M, Nagata H, Asakura H, Tsuchiya M (1987) Increased respiratory burst of leukocytes in inflammatory bowel diseases: the analysis of free radical generation by using chemiluminescence probe. J Clin Lab Immunol 24: 125-128
-
(1987)
J Clin Lab Immunol
, vol.24
, pp. 125-128
-
-
Suematsu, M.1
Suzuki, M.2
Kitahora, T.3
Miura, S.4
Suzuki, K.5
Hibi, T.6
Watanabe, M.7
Nagata, H.8
Asakura, H.9
Tsuchiya, M.10
-
48
-
-
0026742553
-
Mortality of workers exposed to acrylonitrile
-
Swaen GMH, Bloemen LJN, Scheffers T, Slangen JJM, Sturmaus F (1992) Mortality of workers exposed to acrylonitrile. J Occup Med 34: 801-809
-
(1992)
J Occup Med
, vol.34
, pp. 801-809
-
-
Swaen, G.M.H.1
Bloemen, L.J.N.2
Scheffers, T.3
Slangen, J.J.M.4
Sturmaus, F.5
-
49
-
-
0023598056
-
High to low dose extrapolation: Critical determinants involved in the dose response of carcinogenic substances
-
Swenberg JA, Richardson BJ (1987) High to low dose extrapolation: critical determinants involved in the dose response of carcinogenic substances. Environ Health Perspect 76: 57-63
-
(1987)
Environ Health Perspect
, vol.76
, pp. 57-63
-
-
Swenberg, J.A.1
Richardson, B.J.2
-
50
-
-
0026576623
-
Glutathione, protein sulfhydryls and cysteine proteases in gastric mucosal injury and protection
-
Szabo S, Nagy L, Plebani M (1992) Glutathione, protein sulfhydryls and cysteine proteases in gastric mucosal injury and protection. Clin Chim Acta 206: 95-105
-
(1992)
Clin Chim Acta
, vol.206
, pp. 95-105
-
-
Szabo, S.1
Nagy, L.2
Plebani, M.3
-
51
-
-
0023640335
-
Urinary excretion of mercapturic acids and thiocyanate in rats exposed to acrylonitrile: Influence of dose and route of administration
-
Tardif R, Talbot D, Guerin M, Brodeur J (1987) Urinary excretion of mercapturic acids and thiocyanate in rats exposed to acrylonitrile: influence of dose and route of administration. Toxicol Lett 39: 255-261
-
(1987)
Toxicol Lett
, vol.39
, pp. 255-261
-
-
Tardif, R.1
Talbot, D.2
Guerin, M.3
Brodeur, J.4
-
52
-
-
0026093495
-
An overview of the relationships between oxidative stress and chemical carcinogenesis
-
Trush MA, Kensler TW (1991) An overview of the relationships between oxidative stress and chemical carcinogenesis. Free Radical Biol Med 10: 345-347
-
(1991)
Free Radical Biol Med
, vol.10
, pp. 345-347
-
-
Trush, M.A.1
Kensler, T.W.2
-
53
-
-
0343309519
-
Occupational exposure of acrylonitrile (Vinyl cyanide). Proposed standard and notice of hearing
-
US Dept of Labor (1979) Occupational exposure of acrylonitrile (Vinyl cyanide). Proposed standard and notice of hearing. Fed Regul 43: 2586-2621
-
(1979)
Fed Regul
, vol.43
, pp. 2586-2621
-
-
-
54
-
-
0012188518
-
Tobacco and tobacco smoke
-
Academic Press Publication. New York
-
Wynder EL, Hoffmann D (1967) Tobacco and tobacco smoke. Stud Exp Carcinog. Academic Press Publication. New York, pp 450-451
-
(1967)
Stud Exp Carcinog
, pp. 450-451
-
-
Wynder, E.L.1
Hoffmann, D.2
|