Neurotrophins and their receptors in the adult hypo- and hyperthyroid rat after kainic acid injection: An in situ hybridization study

European Journal of Neuroscience

Volumn 8, Issue 9, 1996, Pages 1873-1881

  Calza L ^a,b   Giardino, L ^c   Ceccatelli, S ^d   Hokfelt T ^e  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b Pathophysiology Ctr for the Nerv   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d Department of Environmental Medicine ^*  (Sweden)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

BDNF; NGF; Thyroid hormone; trk

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; KAINIC ACID; MESSENGER RNA; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN; NEUROTROPHIN RECEPTOR; PROTEIN TYROSINE KINASE; THYROID HORMONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BRAIN FUNCTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HYPERTHYROIDISM; HYPOTHYROIDISM; IN SITU HYBRIDIZATION; MALE; MENTAL DISEASE; METABOLISM; MOLECULAR BIOLOGY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

EID: 0029767482     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01331.x     Document Type: Article

References (14)

1. Alvarez-Dolado, M., Iglesias, T., Rodriguez-Pena, A., Bemal, J. and Munoz, A. (1994) Expression of neurotrophins and the trk family of neurotrophin receptors in normal and hypothyroid rat brain. Mol. Brain Res., 27, 249-257.
2. Aniello, F., Couchie, D., Bridoux, A.-M., Gripois, D. and Nunez, J. (1991) Splicing of juvenile and adult tau mRNA variants is regulated by thyroid hormone. Proc. Natl Acad. Sci. USA, 88, 4035-4039.
3. Ballarin, M., Ernfors, P., Lindefors, N. and Persson, H. (1991) Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain. Exp. Neurol., 114, 35-43.
4. Bengzon, J., Kokaia, Z., Ernfors, P., Kokaia, M., Leanza, G., Nilsson, O. G., Persson, H. and Lindvall, O. ( 1993) Regulation of neurotrophin and trkA, trkB and trkC tyrosine kinase receptor messenger RNA expression in kindling. Neuroscience, 53, 433-446.
5. Black, M. A., Pope, L., Lefebvre, F.-A., Lefebvre, Y. A. and Walker, P. (1992) Thyroid hormones precociously increase nerve growth factor gene expression in the submandibular gland of neonatal mice. Endocrinology, 130, 2083-2090.
6. Bothwell, M. (1995) Functional interactions of neurotrophins and neurotrophin receptors. Annu. Rev. Neurosci., 18, 223-253.
7. 2 subtype, in the developing mammalian nervous system. J. Neurosci., 12, 2288-2302.
8. Charrasse, S., Jehan, F., Confort, C., Brachet, P. and Clos, J. (1992) Thyroid hormone promotes transient nerve growth factor synthesis in rat cerebellar neuroblasts. Dev. Neurosci., 14, 282-289.
9. Clos, J. and Lagrand, C. (1990) An interaction between thyroid hormone and nerve growth factor promotes the development of hippocampus, olfactory bulbs and cerebellum: a comparative biochemical study of normal and hypothyroid rats. Growth Factors, 3, 205-220.
10. Cook, C. B. and Koenig, R. J. (1990) Expression of erb-A alpha and beta mRNAs in regions of the adult brain. Mol. Cell. Endocrinol., 70, 13-20.
11. Curran, T., Gordon, M. B., Rubino, K. L. and Sambucetti, L. C. (1987) Isolation and characterization of the c-fos (rat) cDNA and analysis of post-translational modification in vitro. Oncogene, 2, 79-84.
12. Duaich-Djordjevic, M. M., Tocco, G., Lapchak, P. A., Pasinetti, G. M., Najm, I., Baudry, M. and Hefti, F. (1992) Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizure induced by systemic administration of kainic acid. Neuroscience, 47, 303-315.
13. Dugich-Djordjevic, M. M., Ohsawa, F., Okazaki, T., Mori, N., Day, J. R., Beck, K. D. and Hefti, F. (1995) Differential regulation of catalytic and non-catalytic trkB messenger RNAs in the rat hippocampus following seizures induced by systemic administration of kainate. Neuroscience, 66, 861-877.
14. Eide, F. F., Lowenstein, D. H. and Reichardt, L. F. (1993) Neurotrophins and their receptors - current concepts and implications for neurological disease. Exp. Neurol., 121, 200-214.